P57320 (ILVH_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acetolactate synthase small subunit
EC=2.2.1.6

Alternative name(s):
Acetohydroxy-acid synthase small subunit
Short name=AHAS
Short name=ALS

Gene names

Name:	ilvH
Ordered Locus Names:	BU225

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)

Taxonomic identifier

107806 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	158 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 pyruvate = 2-acetolactate + CO2.
Pathway	Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4. Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.
Subunit structure	Dimer of large and small chains By similarity.
Sequence similarities	Belongs to the acetolactate synthase small subunit family. Contains 1 ACT domain.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Branched-chain amino acid biosynthesis
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	branched chain family amino acid biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	acetolactate synthase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 158	158	Acetolactate synthase small subunit		PRO_0000151407
Regions
	Domain	3 – 76	74	ACT

Sequences

	Sequence		Length	Mass (Da)
	P57320 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 74E4EC378D5B6C6B	FASTA	158	17,845
	10 20 30 40 50 60 MRRILSILLE NESGALSRVI GLFSQRGYNI ETITLAPTED PTLSKMTIQT VGNEKAIEQI 70 80 90 100 110 120 EKQLHKLIDV LRVVQIGQSS HIEREIVLLK VQINNHRRDD IKHITEVFRG QIVDITSATY 130 140 150 ILQLSGTTKK IDAFLKIIRN FSEIIEVTRS GIVGISRG

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: APS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000003 Genomic DNA. Translation: BAB12941.1.
RefSeq	NP_240055.1. NC_002528.1.
3D structure databases
ProteinModelPortal	P57320.
SMR	P57320. Positions 2-158.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000003240; EBBUCP00000003016; EBBUCG00000003240.
GeneID	1109668.
GenomeReviews	Gene locus BU225 in contig BA000003_GR.
KEGG	buc:BU225.
PATRIC	21243972. VBIBucAph127364_0238.
Phylogenomic databases
GeneTree	EBGT00050000007745.
HOGENOM	HBG335310.
OMA	IERELAM.
PhylomeDB	P57320.
ProtClustDB	CLSK315804.
Enzyme and pathway databases
BioCyc	BSP107806:BU225-MONOMER.
Family and domain databases
InterPro	IPR004789. Acetalactate_synth_ssu. IPR019455. Acetolactate_synth_ssu_C. IPR002912. ACT-bd. [Graphical view]
KO	K01653.
Pfam	PF01842. ACT. 1 hit. PF10369. ALS_ss_C. 1 hit. [Graphical view]
TIGRFAMs	TIGR00119. Acolac_sm. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ILVH_BUCAI

Accession

Primary (citable) accession number: P57320

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program