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P57312

- FTSW_BUCAI

UniProt

P57312 - FTSW_BUCAI

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Protein
Lipid II flippase FtsW
Gene
ftsW, BU217
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane By similarity.UniRule annotation

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. peptidoglycan biosynthetic process Source: UniProtKB-KW
  4. regulation of cell shape Source: UniProtKB-KW
  5. transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell division, Cell shape, Cell wall biogenesis/degradation, Peptidoglycan synthesis, Transport

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-216-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Lipid II flippase FtsW
Alternative name(s):
Cell division protein FtsW
Gene namesi
Name:ftsW
Ordered Locus Names:BU217
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

Cell membrane; Multi-pass membrane protein By similarity
Note: Localizes to the division septum By similarity.UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei33 – 5321Helical; Reviewed prediction
Add
BLAST
Transmembranei71 – 9121Helical; Reviewed prediction
Add
BLAST
Transmembranei98 – 11821Helical; Reviewed prediction
Add
BLAST
Transmembranei160 – 18021Helical; Reviewed prediction
Add
BLAST
Transmembranei182 – 20221Helical; Reviewed prediction
Add
BLAST
Transmembranei204 – 22421Helical; Reviewed prediction
Add
BLAST
Transmembranei287 – 30721Helical; Reviewed prediction
Add
BLAST
Transmembranei324 – 34421Helical; Reviewed prediction
Add
BLAST
Transmembranei359 – 37921Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 399399Lipid II flippase FtsWUniRule annotation
PRO_0000062697Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the SEDS family. FtsW subfamily.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG0772.
HOGENOMiHOG000282689.
KOiK03588.
OMAiFWNPWDD.
OrthoDBiEOG68M4JQ.

Family and domain databases

HAMAPiMF_00913. FtsW_proteobact.
InterProiIPR018365. Cell_cycle_FtsW-rel_CS.
IPR001182. Cell_cycle_FtsW/RodA.
IPR013437. Cell_div_FtsW.
[Graphical view]
PfamiPF01098. FTSW_RODA_SPOVE. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02614. ftsW. 1 hit.
PROSITEiPS00428. FTSW_RODA_SPOVE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57312-1 [UniParc]FASTAAdd to Basket

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MKHLQKKNSK NPKKIEEKYN TRNSYFILYD RALVWLTLGL FSVGLIMVIS    50
TSIPISQKIY HNPLFFIKRE IFYFFLIFLL SFIFLRTPII FWEKNSNIIL 100
IISIVLLVLV LLIGHSIHGS FRWINIGFLH IQPSEICKIS SFCYLASYLS 150
RKSNEVRNNF WGFFKPMSVI ITQSMLLLAE PDLGTVVVLF FTTISVLFLS 200
GAKIGQFFII ITVSILTIIL LILLEPYRIK RVLSFWNPWE DPFGNGYQLT 250
QSLIALGRGN FLGQGLGNSI QKLDYLPDAH SDFIFSIIGE ELGYIGSFLI 300
LLIIFTISFR AMYIGQKALE KKQIFSGFLA CSIGIWLSFQ TSINVGSVTG 350
ILPTKGLTLP FISYGGSSLI INSIAIFFLL RIDFETRLKT SQAFPRGPK 399
Length:399
Mass (Da):45,458
Last modified:December 1, 2000 - v1
Checksum:iE92E3A94A88C1A8C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12933.1.
RefSeqiNP_240047.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12933; BAB12933; BAB12933.
GeneIDi1109660.
KEGGibuc:BU217.
PATRICi21243956. VBIBucAph127364_0230.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12933.1 .
RefSeqi NP_240047.1. NC_002528.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB12933 ; BAB12933 ; BAB12933 .
GeneIDi 1109660.
KEGGi buc:BU217.
PATRICi 21243956. VBIBucAph127364_0230.

Phylogenomic databases

eggNOGi COG0772.
HOGENOMi HOG000282689.
KOi K03588.
OMAi FWNPWDD.
OrthoDBi EOG68M4JQ.

Enzyme and pathway databases

BioCyci BAPH107806:GBZJ-216-MONOMER.

Family and domain databases

HAMAPi MF_00913. FtsW_proteobact.
InterProi IPR018365. Cell_cycle_FtsW-rel_CS.
IPR001182. Cell_cycle_FtsW/RodA.
IPR013437. Cell_div_FtsW.
[Graphical view ]
Pfami PF01098. FTSW_RODA_SPOVE. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02614. ftsW. 1 hit.
PROSITEi PS00428. FTSW_RODA_SPOVE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiFTSW_BUCAI
AccessioniPrimary (citable) accession number: P57312
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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