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P57312 (FTSW_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lipid II flippase FtsW
Alternative name(s):
Cell division protein FtsW
Gene names
Name:ftsW
Ordered Locus Names:BU217
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length399 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Essential cell division protein. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane By similarity. HAMAP-Rule MF_00913

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity. Note: Localizes to the division septum By similarity. HAMAP-Rule MF_00913

Sequence similarities

Belongs to the SEDS family. FtsW subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 399399Lipid II flippase FtsW HAMAP-Rule MF_00913
PRO_0000062697

Regions

Transmembrane33 – 5321Helical; Potential
Transmembrane71 – 9121Helical; Potential
Transmembrane98 – 11821Helical; Potential
Transmembrane160 – 18021Helical; Potential
Transmembrane182 – 20221Helical; Potential
Transmembrane204 – 22421Helical; Potential
Transmembrane287 – 30721Helical; Potential
Transmembrane324 – 34421Helical; Potential
Transmembrane359 – 37921Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P57312 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: E92E3A94A88C1A8C

FASTA39945,458
        10         20         30         40         50         60 
MKHLQKKNSK NPKKIEEKYN TRNSYFILYD RALVWLTLGL FSVGLIMVIS TSIPISQKIY 

        70         80         90        100        110        120 
HNPLFFIKRE IFYFFLIFLL SFIFLRTPII FWEKNSNIIL IISIVLLVLV LLIGHSIHGS 

       130        140        150        160        170        180 
FRWINIGFLH IQPSEICKIS SFCYLASYLS RKSNEVRNNF WGFFKPMSVI ITQSMLLLAE 

       190        200        210        220        230        240 
PDLGTVVVLF FTTISVLFLS GAKIGQFFII ITVSILTIIL LILLEPYRIK RVLSFWNPWE 

       250        260        270        280        290        300 
DPFGNGYQLT QSLIALGRGN FLGQGLGNSI QKLDYLPDAH SDFIFSIIGE ELGYIGSFLI 

       310        320        330        340        350        360 
LLIIFTISFR AMYIGQKALE KKQIFSGFLA CSIGIWLSFQ TSINVGSVTG ILPTKGLTLP 

       370        380        390 
FISYGGSSLI INSIAIFFLL RIDFETRLKT SQAFPRGPK 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB12933.1.
RefSeqNP_240047.1. NC_002528.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB12933; BAB12933; BAB12933.
GeneID1109660.
KEGGbuc:BU217.
PATRIC21243956. VBIBucAph127364_0230.

Phylogenomic databases

eggNOGCOG0772.
HOGENOMHOG000282689.
KOK03588.
OMAWFSFQTL.
OrthoDBEOG68M4JQ.
ProtClustDBCLSK315799.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-216-MONOMER.

Family and domain databases

HAMAPMF_00913. FtsW_proteobact.
InterProIPR018365. Cell_cycle_FtsW-rel_CS.
IPR001182. Cell_cycle_FtsW/RodA.
IPR013437. Cell_div_FtsW.
[Graphical view]
PfamPF01098. FTSW_RODA_SPOVE. 1 hit.
[Graphical view]
TIGRFAMsTIGR02614. ftsW. 1 hit.
PROSITEPS00428. FTSW_RODA_SPOVE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameFTSW_BUCAI
AccessionPrimary (citable) accession number: P57312
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: February 19, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names