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P57273 (PTA_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphate acetyltransferase

EC=2.3.1.8
Alternative name(s):
Phosphotransacetylase
Gene names
Name:pta
Ordered Locus Names:BU176
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length708 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in acetate metabolism By similarity.

Catalytic activity

Acetyl-CoA + phosphate = CoA + acetyl phosphate.

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.

Subunit structure

Homohexamer By similarity.

Subcellular location

Cytoplasm Potential.

Domain

The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site By similarity.

Sequence similarities

In the N-terminal section; belongs to the CobB/CobQ family.

In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionAcyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionphosphate acetyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 708708Phosphate acetyltransferase
PRO_0000179122

Regions

Region388 – 708321Phosphate acetyltransferase

Sequences

Sequence LengthMass (Da)Tools
P57273 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 1EDC4394824ED89A

FASTA70880,770
        10         20         30         40         50         60 
MSRIIMLIPL DKDIGLTSIG LSIIYFFYQK KIKKKSVQSI LYFSCTQNSS NSTSHVINKY 

        70         80         90        100        110        120 
FSKIVHTVDY IDFSKVLFNS PEYSFLLNKV IDEHYNNKFL RELILIEGIK NNYCINSEEM 

       130        140        150        160        170        180 
NYDISQNLNA EVIFIANLEN SSPEYIKNKE KKINFFLKQK KYKNILGVIF NQINSPFLEN 

       190        200        210        220        230        240 
KYDFIKKLIV LKKIKNETKT IVPKKILKNN FFSIIACIPW NRNIVTTRVI DLFNFLNIQH 

       250        260        270        280        290        300 
TNLVQKKNHI IEEIIIFDTH HLNLLNKHSL NTLVIVSFSR VDVFLNVLNC NVNRSKVKCI 

       310        320        330        340        350        360 
ILTGILKLKK NIASLYKFLI KRSISIFFTE KNTIEILSQL QNFNFDISVK DITYIKKLQR 

       370        380        390        400        410        420 
YISNFFCHSS FMFFKKKYNI NVIYPPKEFC YNLKLLSQKK NKRIKLPESY EIRILKSVAI 

       430        440        450        460        470        480 
CSDSNIAQCV LLGDPKKIYS IANDNGINLK KNIEIIDPIS VRQEYLARFL EIRKGKNINE 

       490        500        510        520        530        540 
FSAKKQLEDN TVLATLILES NHVDGLVSGS INTTSDTIRP ALQIIKTNPQ SLLVSSIFFM 

       550        560        570        580        590        600 
LLPNQVLIYG DCAININPTA EELAVIAIQS ADSAKMFGIE PRIAMLSYST GCSGFGCQVE 

       610        620        630        640        650        660 
KVKEATSIIK NRRSDLIIDG PIQYDAAVSN KVAKLKAPSS PISGSANVFI FPDLNSGNIA 

       670        680        690        700 
YKAVQRSSRI VSIGPMLQGL RKPVNDLSRG ASVEDIIYTI ALTSIQSE 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB12893.1.
RefSeqNP_240007.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57273.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP57273.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB12893; BAB12893; BAB12893.
GeneID1109619.
KEGGbuc:BU176.
PATRIC21243870. VBIBucAph127364_0187.

Phylogenomic databases

eggNOGCOG0280.
HOGENOMHOG000053797.
KOK13788.
OMAININPTA.
OrthoDBEOG6BKJ5W.
ProtClustDBCLSK315687.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-175-MONOMER.
UniPathwayUPA00340; UER00459.

Family and domain databases

InterProIPR010766. DRTGG.
IPR016475. P-Actrans_bac.
IPR004614. P_AcTrfase.
IPR002505. PTA_PTB.
[Graphical view]
PfamPF07085. DRTGG. 1 hit.
PF01515. PTA_PTB. 1 hit.
[Graphical view]
PIRSFPIRSF006107. PhpActrans_proteobac. 1 hit.
TIGRFAMsTIGR00651. pta. 1 hit.
ProtoNetSearch...

Entry information

Entry namePTA_BUCAI
AccessionPrimary (citable) accession number: P57273
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: November 13, 2013
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names