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P57272 (ACKA_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetate kinase
EC=2.7.2.1
Alternative name(s):
Acetokinase
Gene names
Name:ackA
Ordered Locus Names:BU175
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length405 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020

ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020

Pathway

Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020

Subcellular location

Cytoplasm By similarity HAMAP MF_00020.

Sequence similarities

Belongs to the acetokinase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processorganic acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

acetate kinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 405405Acetate kinase HAMAP MF_00020
PRO_0000107538

Sequences

Sequence LengthMass (Da)Tools
P57272 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 471AA3FC9EDE9E43

FASTA40545,141
        10         20         30         40         50         60 
MDKKLNNLIL VLNCGSSSIK FAILNPDNKE KYLSGSVECL FLLETYITWQ CLGTKHKKKI 

        70         80         90        100        110        120 
GANVNHKDAL NFIIEQVFSQ QKDIFKNLIG VGHRVVHGGT KIKKSTLIDS NIIKCIQDAS 

       130        140        150        160        170        180 
SFAPLHNPAN LIGIKMIIEK YPSLSRKNIA VFDTSFYCNM PETSFLYAIP YNFYKKYGIR 

       190        200        210        220        230        240 
RYGAHGISHN YVAHRASLML NKQFKSLNII TCHLGNGSSI SAICNGICVD TSMGLTPLEG 

       250        260        270        280        290        300 
LVMGTRSGDL DPSIIFFMNN HLNLSIDKIE TILNKKSGLL GLSGISSDFR YFEKKYYCKK 

       310        320        330        340        350        360 
HAKRSVDIFC HRLSKYIAAY TSVLENRLDA VIFTGGIGEN VPLIRELVFS RLSLLGFKIN 

       370        380        390        400 
SNLNLSTIGG KSGLITEDNS TPVFVITTDE ELAIAQETNS IINRK

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed: 10993077] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000003 Genomic DNA. Translation: BAB12892.1.
RefSeqNP_240006.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57272.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBUCT00000003265; EBBUCP00000003041; EBBUCG00000003265.
GeneID1109618.
GenomeReviewsGene locus BU175 in contig BA000003_GR.
KEGGbuc:BU175.
PATRIC21243868. VBIBucAph127364_0186.

Phylogenomic databases

GeneTreeEBGT00050000008196.
HOGENOMHBG285863.
OMAIVFHLHD.
PhylomeDBP57272.
ProtClustDBPRK00180.

Enzyme and pathway databases

BioCycBSP107806:BU175-MONOMER.

Family and domain databases

HAMAPMF_00020. Acetate_kinase.
[Tree]
InterProIPR004372. Ac/Proprionate_kinase.
IPR000890. Aliphatic_acid_kin_short-chain.
IPR023865. Aliphatic_acid_kinase_CS.
[Graphical view]
KOK00925.
PANTHERPTHR21060. Acetate_kin. 1 hit.
PfamPF00871. Acetate_kinase. 1 hit.
[Graphical view]
PIRSFPIRSF000722. Acetate_prop_kin. 1 hit.
PRINTSPR00471. ACETATEKNASE.
TIGRFAMsTIGR00016. AckA. 1 hit.
PROSITEPS01075. ACETATE_KINASE_1. 1 hit.
PS01076. ACETATE_KINASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACKA_BUCAI
AccessionPrimary (citable) accession number: P57272
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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