Reviewed, UniProtKB/Swiss-Prot P57272 (ACKA_BUCAI)

Names and origin

Protein names

Recommended name:
    Acetate kinase
    EC=2.7.2.1
Alternative name(s):
    Acetokinase

Gene names

Name:	ackA
Ordered Locus Names:	BU175

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	405 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro phosphorylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 405	405	Acetate kinase HAMAP MF_00020		PRO_0000107538

Sequences

	Sequence		Length	Mass (Da)
	P57272-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 471AA3FC9EDE9E43	FASTA	405	45,141
	10 20 30 40 50 60 MDKKLNNLIL VLNCGSSSIK FAILNPDNKE KYLSGSVECL FLLETYITWQ CLGTKHKKKI 70 80 90 100 110 120 GANVNHKDAL NFIIEQVFSQ QKDIFKNLIG VGHRVVHGGT KIKKSTLIDS NIIKCIQDAS 130 140 150 160 170 180 SFAPLHNPAN LIGIKMIIEK YPSLSRKNIA VFDTSFYCNM PETSFLYAIP YNFYKKYGIR 190 200 210 220 230 240 RYGAHGISHN YVAHRASLML NKQFKSLNII TCHLGNGSSI SAICNGICVD TSMGLTPLEG 250 260 270 280 290 300 LVMGTRSGDL DPSIIFFMNN HLNLSIDKIE TILNKKSGLL GLSGISSDFR YFEKKYYCKK 310 320 330 340 350 360 HAKRSVDIFC HRLSKYIAAY TSVLENRLDA VIFTGGIGEN VPLIRELVFS RLSLLGFKIN 370 380 390 400 SNLNLSTIGG KSGLITEDNS TPVFVITTDE ELAIAQETNS IINRK

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000003 Genomic DNA. Translation: BAB12892.1.
RefSeq	NP_240006.1.
3D structure databases
SMR	P57272. Positions 9-404.
ModBase	Search...
Genome annotation databases
GeneID	1109618.
GenomeReviews	Gene locus BU175 in contig BA000003_GR.
KEGG	buc:BU175.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG285863.
OMA	PAIVFHL.
PhylomeDB	P57272.
Enzyme and pathway databases
BioCyc	BSP107806:BU175-MONOMER.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR000890. Acetate/butyrate_kinase. IPR004372. AckA. [Graphical view]
PANTHER	PTHR21060. Acetate_kin. 1 hit. PTHR21060:SF11. AckA. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. ackA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACKA_BUCAI

Accession

Primary (citable) accession number: P57272

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	February 9, 2010
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)