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P57268

- RF1_BUCAI

UniProt

P57268 - RF1_BUCAI

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Protein

Peptide chain release factor 1

Gene

prfA

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.By similarity

GO - Molecular functioni

  1. translation release factor activity, codon specific Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Protein biosynthesis

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide chain release factor 1
Short name:
RF-1
Gene namesi
Name:prfA
Ordered Locus Names:BU171
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Peptide chain release factor 1PRO_0000177646Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei235 – 2351N5-methylglutamineBy similarity

Post-translational modificationi

Methylated by PrmC. Methylation increases the termination efficiency of RF1 (By similarity).By similarity

Keywords - PTMi

Methylation

Structurei

3D structure databases

ProteinModelPortaliP57268.
SMRiP57268. Positions 8-353.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0216.
HOGENOMiHOG000074815.
KOiK02835.
OMAiYGQLKFE.
OrthoDBiEOG6TN48J.

Family and domain databases

Gene3Di3.30.160.20. 1 hit.
HAMAPiMF_00093. Rel_fac_1.
InterProiIPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamiPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTiSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00019. prfA. 1 hit.
PROSITEiPS00745. RF_PROK_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57268-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNSILNKLK SLRNRYQEIE IMLTQKNVIS NRENLKTLSK EYLKLSEIIK
60 70 80 90 100
YFIEWEKLEV DIENVNILLN DVEIQGMAEE ELYFFNKKKK ALEKKINQLL
110 120 130 140 150
LPEDPNDKHS CFIEIRSATG GDESSIFAGE LFRMYLRYAE SYSWKVEIMN
160 170 180 190 200
TSESEKGGFK EIIAKITGRG ACGRLKFESG GHRVQRVPET ESQGRIHTST
210 220 230 240 250
CTVAVMPVTP KTEKEEINSS DLKIDTFRSS GAGGQHVNTT DSAIRITHIP
260 270 280 290 300
TGNVVECQDE RSQHKNKAKA LSILSARVYA AKLEKDRQES SSMRKILLGT
310 320 330 340 350
GERSDRNRTY NFPQNRITDH RINLSIYKLD EVLQGKLDLL IDPIIQEYQA
360
DMLSSLSKSE S
Length:361
Mass (Da):41,262
Last modified:December 1, 2000 - v1
Checksum:iB2F6B2603D15FB99
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12888.1.
RefSeqiNP_240002.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12888; BAB12888; BAB12888.
GeneIDi1109614.
KEGGibuc:BU171.
PATRICi21243860. VBIBucAph127364_0182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12888.1 .
RefSeqi NP_240002.1. NC_002528.1.

3D structure databases

ProteinModelPortali P57268.
SMRi P57268. Positions 8-353.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB12888 ; BAB12888 ; BAB12888 .
GeneIDi 1109614.
KEGGi buc:BU171.
PATRICi 21243860. VBIBucAph127364_0182.

Phylogenomic databases

eggNOGi COG0216.
HOGENOMi HOG000074815.
KOi K02835.
OMAi YGQLKFE.
OrthoDBi EOG6TN48J.

Enzyme and pathway databases

BioCyci BAPH107806:GBZJ-170-MONOMER.

Family and domain databases

Gene3Di 3.30.160.20. 1 hit.
HAMAPi MF_00093. Rel_fac_1.
InterProi IPR014720. dsRNA-bd_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view ]
Pfami PF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view ]
SMARTi SM00937. PCRF. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00019. prfA. 1 hit.
PROSITEi PS00745. RF_PROK_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiRF1_BUCAI
AccessioniPrimary (citable) accession number: P57268
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: October 29, 2014
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3