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P57268 (RF1_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Peptide chain release factor 1
Short name=RF-1
Gene names
Name:prfA
Ordered Locus Names:BU171
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera ›

Protein attributes

Sequence length361 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA By similarity. HAMAP-Rule MF_00093

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00093.

Post-translational modification

Methylated by PrmC. Methylation increases the termination efficiency of RF1 By similarity. HAMAP-Rule MF_00093

Sequence similarities

Belongs to the prokaryotic/mitochondrial release factor family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   PTMMethylation
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functiontranslation release factor activity, codon specific

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 361361Peptide chain release factor 1 HAMAP-Rule MF_00093
PRO_0000177646

Amino acid modifications

Modified residue2351N5-methylglutamine By similarity

Sequences

Sequence LengthMass (Da)Tools
P57268 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: B2F6B2603D15FB99

FASTA36141,262
        10         20         30         40         50         60 
MNNSILNKLK SLRNRYQEIE IMLTQKNVIS NRENLKTLSK EYLKLSEIIK YFIEWEKLEV 

        70         80         90        100        110        120 
DIENVNILLN DVEIQGMAEE ELYFFNKKKK ALEKKINQLL LPEDPNDKHS CFIEIRSATG 

       130        140        150        160        170        180 
GDESSIFAGE LFRMYLRYAE SYSWKVEIMN TSESEKGGFK EIIAKITGRG ACGRLKFESG 

       190        200        210        220        230        240 
GHRVQRVPET ESQGRIHTST CTVAVMPVTP KTEKEEINSS DLKIDTFRSS GAGGQHVNTT 

       250        260        270        280        290        300 
DSAIRITHIP TGNVVECQDE RSQHKNKAKA LSILSARVYA AKLEKDRQES SSMRKILLGT 

       310        320        330        340        350        360 
GERSDRNRTY NFPQNRITDH RINLSIYKLD EVLQGKLDLL IDPIIQEYQA DMLSSLSKSE 


S

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000003 Genomic DNA. Translation: BAB12888.1.
RefSeqNP_240002.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57268.
SMRP57268. Positions 8-353.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB12888; BAB12888; BAB12888.
GeneID1109614.
KEGGbuc:BU171.
PATRIC21243860. VBIBucAph127364_0182.

Phylogenomic databases

eggNOGCOG0216.
HOGENOMHOG000074815.
KOK02835.
OMAEMPEINP.
ProtClustDBPRK00591.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-170-MONOMER.

Family and domain databases

Gene3D3.30.160.20. 1 hit.
HAMAPMF_00093. Rel_fac_1.
InterProIPR014720. dsRNA-bd-like_dom.
IPR005139. PCRF.
IPR000352. Pep_chain_release_fac_I_II.
IPR004373. PrfA.
[Graphical view]
PfamPF03462. PCRF. 1 hit.
PF00472. RF-1. 1 hit.
[Graphical view]
SMARTSM00937. PCRF. 1 hit.
[Graphical view]
TIGRFAMsTIGR00019. prfA. 1 hit.
PROSITEPS00745. RF_PROK_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRF1_BUCAI
AccessionPrimary (citable) accession number: P57268
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 29, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names

SIMILARITY comments

Index of protein domains and families

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