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P57268

- RF1_BUCAI

UniProt

P57268 - RF1_BUCAI

Protein

Peptide chain release factor 1

Gene

prfA

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Dec 2000)
      Previous versions | rss
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    Functioni

    Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.By similarity

    GO - Molecular functioni

    1. translation release factor activity, codon specific Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Protein biosynthesis

    Enzyme and pathway databases

    BioCyciBAPH107806:GBZJ-170-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Peptide chain release factor 1
    Short name:
    RF-1
    Gene namesi
    Name:prfA
    Ordered Locus Names:BU171
    OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
    Taxonomic identifieri107806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000001806: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 361361Peptide chain release factor 1PRO_0000177646Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei235 – 2351N5-methylglutamineBy similarity

    Post-translational modificationi

    Methylated by PrmC. Methylation increases the termination efficiency of RF1 By similarity.By similarity

    Keywords - PTMi

    Methylation

    Structurei

    3D structure databases

    ProteinModelPortaliP57268.
    SMRiP57268. Positions 8-353.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0216.
    HOGENOMiHOG000074815.
    KOiK02835.
    OMAiYGQLKFE.
    OrthoDBiEOG6TN48J.

    Family and domain databases

    Gene3Di3.30.160.20. 1 hit.
    HAMAPiMF_00093. Rel_fac_1.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR004373. PrfA.
    [Graphical view]
    PfamiPF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view]
    SMARTiSM00937. PCRF. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00019. prfA. 1 hit.
    PROSITEiPS00745. RF_PROK_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P57268-1 [UniParc]FASTAAdd to Basket

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    MNNSILNKLK SLRNRYQEIE IMLTQKNVIS NRENLKTLSK EYLKLSEIIK    50
    YFIEWEKLEV DIENVNILLN DVEIQGMAEE ELYFFNKKKK ALEKKINQLL 100
    LPEDPNDKHS CFIEIRSATG GDESSIFAGE LFRMYLRYAE SYSWKVEIMN 150
    TSESEKGGFK EIIAKITGRG ACGRLKFESG GHRVQRVPET ESQGRIHTST 200
    CTVAVMPVTP KTEKEEINSS DLKIDTFRSS GAGGQHVNTT DSAIRITHIP 250
    TGNVVECQDE RSQHKNKAKA LSILSARVYA AKLEKDRQES SSMRKILLGT 300
    GERSDRNRTY NFPQNRITDH RINLSIYKLD EVLQGKLDLL IDPIIQEYQA 350
    DMLSSLSKSE S 361
    Length:361
    Mass (Da):41,262
    Last modified:December 1, 2000 - v1
    Checksum:iB2F6B2603D15FB99
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB12888.1.
    RefSeqiNP_240002.1. NC_002528.1.

    Genome annotation databases

    EnsemblBacteriaiBAB12888; BAB12888; BAB12888.
    GeneIDi1109614.
    KEGGibuc:BU171.
    PATRICi21243860. VBIBucAph127364_0182.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB12888.1 .
    RefSeqi NP_240002.1. NC_002528.1.

    3D structure databases

    ProteinModelPortali P57268.
    SMRi P57268. Positions 8-353.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB12888 ; BAB12888 ; BAB12888 .
    GeneIDi 1109614.
    KEGGi buc:BU171.
    PATRICi 21243860. VBIBucAph127364_0182.

    Phylogenomic databases

    eggNOGi COG0216.
    HOGENOMi HOG000074815.
    KOi K02835.
    OMAi YGQLKFE.
    OrthoDBi EOG6TN48J.

    Enzyme and pathway databases

    BioCyci BAPH107806:GBZJ-170-MONOMER.

    Family and domain databases

    Gene3Di 3.30.160.20. 1 hit.
    HAMAPi MF_00093. Rel_fac_1.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR005139. PCRF.
    IPR000352. Pep_chain_release_fac_I_II.
    IPR004373. PrfA.
    [Graphical view ]
    Pfami PF03462. PCRF. 1 hit.
    PF00472. RF-1. 1 hit.
    [Graphical view ]
    SMARTi SM00937. PCRF. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00019. prfA. 1 hit.
    PROSITEi PS00745. RF_PROK_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
      Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
      Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: APS.

    Entry informationi

    Entry nameiRF1_BUCAI
    AccessioniPrimary (citable) accession number: P57268
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: December 1, 2000
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
      Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3