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P57262

- NUOL_BUCAI

UniProt

P57262 - NUOL_BUCAI

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Protein

NADH-quinone oxidoreductase subunit L

Gene
nuoL, BU164
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity.

Catalytic activityi

NADH + quinone = NAD+ + quinol.

GO - Molecular functioni

  1. NADH dehydrogenase (ubiquinone) activity Source: InterPro
  2. quinone binding Source: UniProtKB-KW

GO - Biological processi

  1. ATP synthesis coupled electron transport Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NAD

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-164-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-quinone oxidoreductase subunit L (EC:1.6.99.5)
Alternative name(s):
NADH dehydrogenase I subunit L
NDH-1 subunit L
Gene namesi
Name:nuoL
Ordered Locus Names:BU164
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei1 – 2121Helical; Reviewed predictionAdd
BLAST
Transmembranei33 – 5321Helical; Reviewed predictionAdd
BLAST
Transmembranei79 – 9921Helical; Reviewed predictionAdd
BLAST
Transmembranei136 – 15621Helical; Reviewed predictionAdd
BLAST
Transmembranei168 – 18821Helical; Reviewed predictionAdd
BLAST
Transmembranei207 – 22721Helical; Reviewed predictionAdd
BLAST
Transmembranei247 – 26721Helical; Reviewed predictionAdd
BLAST
Transmembranei271 – 29121Helical; Reviewed predictionAdd
BLAST
Transmembranei327 – 34721Helical; Reviewed predictionAdd
BLAST
Transmembranei372 – 39221Helical; Reviewed predictionAdd
BLAST
Transmembranei410 – 43021Helical; Reviewed predictionAdd
BLAST
Transmembranei455 – 47521Helical; Reviewed predictionAdd
BLAST
Transmembranei492 – 51221Helical; Reviewed predictionAdd
BLAST
Transmembranei533 – 55321Helical; Reviewed predictionAdd
BLAST
Transmembranei593 – 61321Helical; Reviewed predictionAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 614614NADH-quinone oxidoreductase subunit LPRO_0000118214Add
BLAST

Keywords - PTMi

Quinone

Interactioni

Subunit structurei

Composed of 13 different subunits. Subunits NuoA, H, J, K, L, M, N constitute the membrane sector of the complex By similarity.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1009.
HOGENOMiHOG000100570.
KOiK00341.
OMAiRFFSYMN.
OrthoDBiEOG6FZ48R.

Family and domain databases

InterProiIPR001750. NADH_UbQ/plastoQ_OxRdtase.
IPR001516. NADH_UbQ_OxRdtase_chain5/L_N.
IPR003945. NADHpl_OxRdtase_5.
IPR018393. NADHpl_OxRdtase_5_subgr.
[Graphical view]
PfamiPF00361. Oxidored_q1. 1 hit.
PF00662. Oxidored_q1_N. 1 hit.
[Graphical view]
PRINTSiPR01435. NPOXDRDTASE5.
TIGRFAMsiTIGR01974. NDH_I_L. 1 hit.

Sequencei

Sequence statusi: Complete.

P57262-1 [UniParc]FASTAAdd to Basket

« Hide

MSIIFFIILF PLIGFLFLST IQDFIFKRYT LNIGIFSIFI SFFITCFYGV    50
SILKNNNQVF TQILWKWLSI NEFKIDFGFF LDGLSLSMLF VITGVGLLIH 100
IFSSWYMRYK EGQSRFFAYT NLFIASMSVL VLADNFLFMY LGWEGVSVCS 150
YLLIGFYYTE LKNNLCAFKA FILTRVSDVF LMIGMFLIYR EFNSFNFQEI 200
KFLSSFLNVE NFYYLDYITL FLLLGVIGKS AQLPLQTWLS DAMVGPTPVS 250
ALIHAATMVT AGVYLIARTH FLFLLTPGIL YLVGLIGTLT ILVSSISALV 300
QKDIKRILAY STMSQIGYMF LALGVKAWSA AITHLIMHAI FKALLFLSAG 350
SLIKSCKNEK NIFKMGGLRK QLPFLYISFI VGGASLVSFP LITAGFYSKG 400
NILFSVLKSG CIDFFIIGLF CSFLTAIYTF RMIFVIFHGK NIHTADSSTN 450
LQHNIPLFVL LLLSTVFGSY ISPPLSDVFP LSYTPIDHKF AFEIICSILS 500
LSGIYLSYYI WIKNLYVLDK IFQFKFMRYL YYFFLKGWGF NWFYKISFVY 550
FYLYISKRLS ADPLNKIINY FLKVTQIFNF YLLKTSNGYV RWYVASMILG 600
INFIFLLMLF FYFN 614
Length:614
Mass (Da):70,882
Last modified:December 1, 2000 - v1
Checksum:i18CCC2DFC4FE27E0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12882.1.
RefSeqiNP_239996.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12882; BAB12882; BAB12882.
GeneIDi1109608.
KEGGibuc:BU164.
PATRICi21243844. VBIBucAph127364_0174.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12882.1 .
RefSeqi NP_239996.1. NC_002528.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB12882 ; BAB12882 ; BAB12882 .
GeneIDi 1109608.
KEGGi buc:BU164.
PATRICi 21243844. VBIBucAph127364_0174.

Phylogenomic databases

eggNOGi COG1009.
HOGENOMi HOG000100570.
KOi K00341.
OMAi RFFSYMN.
OrthoDBi EOG6FZ48R.

Enzyme and pathway databases

BioCyci BAPH107806:GBZJ-164-MONOMER.

Family and domain databases

InterProi IPR001750. NADH_UbQ/plastoQ_OxRdtase.
IPR001516. NADH_UbQ_OxRdtase_chain5/L_N.
IPR003945. NADHpl_OxRdtase_5.
IPR018393. NADHpl_OxRdtase_5_subgr.
[Graphical view ]
Pfami PF00361. Oxidored_q1. 1 hit.
PF00662. Oxidored_q1_N. 1 hit.
[Graphical view ]
PRINTSi PR01435. NPOXDRDTASE5.
TIGRFAMsi TIGR01974. NDH_I_L. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiNUOL_BUCAI
AccessioniPrimary (citable) accession number: P57262
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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