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P57255 (NUOE_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified December 11, 2013. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADH-quinone oxidoreductase subunit E

EC=1.6.99.5
Alternative name(s):
NADH dehydrogenase I subunit E
NDH-1 subunit E
Gene names
Name:nuoE
Ordered Locus Names:BU157
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length162 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient By similarity.

Catalytic activity

NADH + quinone = NAD+ + quinol.

Cofactor

Binds 1 2Fe-2S cluster Potential.

Subunit structure

Composed of 13 different subunits. Subunits NuoCD, E, F, and G constitute the peripheral sector of the complex By similarity.

Sequence similarities

Belongs to the complex I 24 kDa subunit family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 162162NADH-quinone oxidoreductase subunit E
PRO_0000118688

Sites

Metal binding881Iron-sulfur (2Fe-2S) Potential
Metal binding931Iron-sulfur (2Fe-2S) Potential
Metal binding1291Iron-sulfur (2Fe-2S) Potential
Metal binding1331Iron-sulfur (2Fe-2S) Potential

Sequences

Sequence LengthMass (Da)Tools
P57255 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 428DC8DBA0B463F1

FASTA16218,598
        10         20         30         40         50         60 
MQEISIKFKL TNEEINAIEN QKKYYEDFRA ISIEALKIVQ KKRGWVSDQA IYAIAEILHI 

        70         80         90        100        110        120 
NPSDVEGVAT FYSQIFRKPV GRNIIRYCDS VVCFLTGYKR IQIALENYLK IKIGETTKDD 

       130        140        150        160 
RFTLLPVCCL GNCDKGPTIM INEDTYSVLT PESIPSLLES YK 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB12875.1.
RefSeqNP_239989.1. NC_002528.1.

3D structure databases

ProteinModelPortalP57255.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB12875; BAB12875; BAB12875.
GeneID1109601.
KEGGbuc:BU157.
PATRIC21243830. VBIBucAph127364_0167.

Phylogenomic databases

eggNOGCOG1905.
HOGENOMHOG000257749.
KOK00334.
OMACHVRGGA.
OrthoDBEOG6T4S12.
ProtClustDBPRK07539.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-157-MONOMER.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
InterProIPR002023. NuoE-like.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PANTHERPTHR10371. PTHR10371. 1 hit.
PfamPF01257. 2Fe-2S_thioredx. 1 hit.
[Graphical view]
PIRSFPIRSF000216. NADH_DH_24kDa. 1 hit.
SUPFAMSSF52833. SSF52833. 1 hit.
TIGRFAMsTIGR01958. nuoE_fam. 1 hit.
PROSITEPS01099. COMPLEX1_24K. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNUOE_BUCAI
AccessionPrimary (citable) accession number: P57255
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: December 11, 2013
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names