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P57240

- SURA_BUCAI

UniProt

P57240 - SURA_BUCAI

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Protein
Chaperone SurA
Gene
surA, BU140
Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation By similarity.UniRule annotation

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotation

GO - Molecular functioni

  1. peptide binding Source: InterPro
  2. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. Gram-negative-bacterium-type cell outer membrane assembly Source: InterPro
  2. biofilm formation Source: InterPro
  3. chaperone mediated protein folding requiring cofactor Source: InterPro
  4. maintenance of stationary phase Source: InterPro
  5. protein stabilization Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Chaperone, Isomerase, Rotamase

Enzyme and pathway databases

BioCyciBAPH107806:GBZJ-140-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Chaperone SurA
Alternative name(s):
Peptidyl-prolyl cis-trans isomerase SurA (EC:5.2.1.8)
Short name:
PPIase SurA
Rotamase SurA
Gene namesi
Name:surA
Ordered Locus Names:BU140
OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifieri107806 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
ProteomesiUP000001806: Chromosome

Subcellular locationi

Periplasm By similarity
Note: Is capable of associating with the outer membrane By similarity.UniRule annotation

GO - Cellular componenti

  1. outer membrane-bounded periplasmic space Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 Reviewed prediction
Add
BLAST
Chaini21 – 430410Chaperone SurAUniRule annotation
PRO_0000025540Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP57240.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini174 – 275102PpiC 1
Add
BLAST
Domaini284 – 384101PpiC 2
Add
BLAST

Domaini

The PPIase activity resides only in the second parvulin domain. The N-terminal region and the C-terminal tail are necessary and sufficient for the chaperone activity of SurA. The PPIase activity is dispensable for SurA to function as a chaperone. The N-terminal region and the C-terminal tail are also required for porin recognition By similarity.UniRule annotation

Sequence similaritiesi

Contains 2 PpiC domains.

Keywords - Domaini

Repeat, Signal

Phylogenomic databases

eggNOGiCOG0760.
HOGENOMiHOG000085868.
KOiK03771.
OMAiLGKMQLS.
OrthoDBiEOG6M9DS4.

Family and domain databases

HAMAPiMF_01183. Chaperone_SurA.
InterProiIPR000297. PPIase_PpiC.
IPR023034. PPIase_SurA.
IPR015391. SurA_N.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view]
PfamiPF00639. Rotamase. 1 hit.
PF09312. SurA_N. 1 hit.
[Graphical view]
SUPFAMiSSF109998. SSF109998. 1 hit.
PROSITEiPS50198. PPIC_PPIASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P57240-1 [UniParc]FASTAAdd to Basket

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MKICIFIFFY IFSSIFYVLA KNNQVDNITA IVNDEIILNS DVNEILVFLK    50
KSKKKFIIPL KSDFLKEKVL EKLIVDSLIL QEANSKNINI TKEQIDTVIK 100
NIALKKHISV DHFKKQILLR NIKNPSYYDN FIKKIEILLK MKTIQDYELH 150
KRINISEQEV NTIFKKLIKD NEKFKKINLS YILLPSLKQD SDNAVRNRTK 200
IAENIVYKLK KGYDFEKLLI ECEKNKSTFI VKKMFWKPLL DIQNSFFKTL 250
NIFKKGQILG PIVGDKGLYI LKVNDIHHKK ENIVTEFYMQ HCLIKPSVIL 300
TNTEAKKKIF NIYENIKKGI YTFDDAVKNL SDDYYSSNKK GDLGWISKES 350
LGFDLNKKFL ILDKNEISEP VKSNWGWHIF KILDRRQVDA FYKLKKNQAF 400
NIVLNQKIIS EKNHWIEDLK NTAYIEIIRS 430
Length:430
Mass (Da):50,738
Last modified:December 1, 2000 - v1
Checksum:iCA4C425B3FBA5788
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12858.1.
RefSeqiNP_239972.1. NC_002528.1.

Genome annotation databases

EnsemblBacteriaiBAB12858; BAB12858; BAB12858.
GeneIDi1109584.
KEGGibuc:BU140.
PATRICi21243794. VBIBucAph127364_0149.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000003 Genomic DNA. Translation: BAB12858.1 .
RefSeqi NP_239972.1. NC_002528.1.

3D structure databases

ProteinModelPortali P57240.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB12858 ; BAB12858 ; BAB12858 .
GeneIDi 1109584.
KEGGi buc:BU140.
PATRICi 21243794. VBIBucAph127364_0149.

Phylogenomic databases

eggNOGi COG0760.
HOGENOMi HOG000085868.
KOi K03771.
OMAi LGKMQLS.
OrthoDBi EOG6M9DS4.

Enzyme and pathway databases

BioCyci BAPH107806:GBZJ-140-MONOMER.

Family and domain databases

HAMAPi MF_01183. Chaperone_SurA.
InterProi IPR000297. PPIase_PpiC.
IPR023034. PPIase_SurA.
IPR015391. SurA_N.
IPR027304. Trigger_fact/SurA_dom.
[Graphical view ]
Pfami PF00639. Rotamase. 1 hit.
PF09312. SurA_N. 1 hit.
[Graphical view ]
SUPFAMi SSF109998. SSF109998. 1 hit.
PROSITEi PS50198. PPIC_PPIASE_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
    Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
    Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: APS.

Entry informationi

Entry nameiSURA_BUCAI
AccessioniPrimary (citable) accession number: P57240
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
    Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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