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P57236 (SYGA_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycine--tRNA ligase alpha subunit
EC=6.1.1.14
Alternative name(s):
Glycyl-tRNA synthetase alpha subunit
Short name=GlyRS
Gene names
Name:glyQ
Ordered Locus Names:BU136
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254

Subunit structure

Tetramer of two alpha and two beta subunits By similarity.

Subcellular location

Cytoplasm HAMAP MF_00254.

Sequence similarities

Belongs to the class-II aminoacyl-tRNA synthetase family.

Sequence caution

The sequence BAB12854.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processglycyl-tRNA aminoacylation

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

glycine-tRNA ligase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 312312Glycine--tRNA ligase alpha subunit HAMAP MF_00254
PRO_0000072830

Sequences

Sequence LengthMass (Da)Tools
P57236 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: A138A9BEBC6CE8C6

FASTA31236,961
        10         20         30         40         50         60 
MKNYHNNFHK LITILQEYWL QQGCTIFQPL DLPIGAGTFH NITFLGTIGP EPINAAYIQS 

        70         80         90        100        110        120 
CRRPSDGRYG ENPNRLQHYY QFQVIIKPPP NNIQNIYLNS LYLLNIDEKI HDIRFVEDNW 

       130        140        150        160        170        180 
ENPTLGAWGI GWEVWLNGME ITQFTYFQQV GGLECKPVSV EITYGLERIA MHMQNKSNVY 

       190        200        210        220        230        240 
DLIWNEYNHK KITYGDIFQQ NEREQSQYNF QYSDVNFLFD CFKKYELEAK KLINLKEPLL 

       250        260        270        280        290        300 
LVSYEKILQA NHIFNLLDAR KSLSSNERQS YILRIRKLTS QVAIKYLNLR KNLGFPLCHK 

       310 
KREIHDKENI IN

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed: 10993077] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000003 Genomic DNA. Translation: BAB12854.1. Different initiation.
RefSeqNP_239968.2. NC_002528.1.

3D structure databases

ProteinModelPortalP57236.
SMRP57236. Positions 7-292.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaEBBUCT00000002770; EBBUCP00000002546; EBBUCG00000002770.
GeneID1109580.
GenomeReviewsGene locus BU136 in contig BA000003_GR.
KEGGbuc:BU136.
PATRIC21243786. VBIBucAph127364_0145.

Phylogenomic databases

GeneTreeEBGT00050000008062.
HOGENOMHBG285316.
OMACRRPTDG.
PhylomeDBP57236.
ProtClustDBPRK09348.

Enzyme and pathway databases

BioCycBSP107806:BU136-MONOMER.

Family and domain databases

HAMAPMF_00254. Gly_tRNA_synth_alpha.
[Tree]
InterProIPR006194. Gly-tRNA-synth_II_heterodimer.
IPR002310. Gly-tRNA_synth_IIc_asu.
[Graphical view]
KOK01878.
PfamPF02091. tRNA-synt_2e. 1 hit.
[Graphical view]
PRINTSPR01044. TRNASYNTHGA.
TIGRFAMsTIGR00388. GlyQ. 1 hit.
PROSITEPS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYGA_BUCAI
AccessionPrimary (citable) accession number: P57236
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names

SIMILARITY comments

Index of protein domains and families

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