Reviewed, UniProtKB/Swiss-Prot P57236 (SYGA_BUCAI)

Names and origin

Protein names

Recommended name:
    Glycyl-tRNA synthetase alpha subunit
    EC=6.1.1.14
Alternative name(s):
    Glycine--tRNA ligase alpha subunit
      Short name=GlyRS

Gene names

Name:	glyQ
Ordered Locus Names:	BU136

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	312 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly). HAMAP MF_00254
Subunit structure	Tetramer of two alpha and two beta subunits By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00254
Sequence similarities	Belongs to the class-II aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP glycine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 312	312	Glycyl-tRNA synthetase alpha subunit HAMAP MF_00254		PRO_0000072830

Sequences

	Sequence		Length	Mass (Da)
	P57236-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: A138A9BEBC6CE8C6	FASTA	312	36,961
	10 20 30 40 50 60 MKNYHNNFHK LITILQEYWL QQGCTIFQPL DLPIGAGTFH NITFLGTIGP EPINAAYIQS 70 80 90 100 110 120 CRRPSDGRYG ENPNRLQHYY QFQVIIKPPP NNIQNIYLNS LYLLNIDEKI HDIRFVEDNW 130 140 150 160 170 180 ENPTLGAWGI GWEVWLNGME ITQFTYFQQV GGLECKPVSV EITYGLERIA MHMQNKSNVY 190 200 210 220 230 240 DLIWNEYNHK KITYGDIFQQ NEREQSQYNF QYSDVNFLFD CFKKYELEAK KLINLKEPLL 250 260 270 280 290 300 LVSYEKILQA NHIFNLLDAR KSLSSNERQS YILRIRKLTS QVAIKYLNLR KNLGFPLCHK 310 KREIHDKENI IN

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000003 Genomic DNA. Translation: BAB12854.1. Different initiation.
RefSeq	NP_239968.2.
3D structure databases
HSSP	HSSP built from PDB template 1J5W based on UniProtKB Q9WY59.
ModBase	Search...
Genome annotation databases
GeneID	1109580.
GenomeReviews	Gene locus BU136 in contig BA000003_GR.
KEGG	buc:BU136.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P57236.
OMA	CRRPTDG.
Enzyme and pathway databases
BioCyc	BSP107806:BU136-MON.
Family and domain databases
HAMAP	MF_00254. [Tree]
InterPro	IPR006194. Gly-tRNA-synth_II_heterodimer. IPR002310. Gly-tRNA_synth_IIc_asu. [Graphical view]
Pfam	PF02091. tRNA-synt_2e. 1 hit. [Graphical view]
PRINTS	PR01044. TRNASYNTHGA.
ProDom	PD006985. tRNA_synt_2e. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00388. glyQ. 1 hit.
PROSITE	PS50861. AA_TRNA_LIGASE_II_GLYAB. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYGA_BUCAI

Accession

Primary (citable) accession number: P57236

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	November 3, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)