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P57209 (DCD_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Deoxycytidine triphosphate deaminase

Short name=dCTP deaminase
EC=3.5.4.13
Gene names
Name:dcd
Ordered Locus Names:BU108
OrganismBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium) [Reference proteome] [HAMAP]
Taxonomic identifier107806 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera

Protein attributes

Sequence length193 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

dCTP + H2O = dUTP + NH3. HAMAP-Rule MF_00146

Pathway

Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2. HAMAP-Rule MF_00146

Sequence similarities

Belongs to the dCTP deaminase family.

Sequence caution

The sequence BAB12827.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdUMP biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

dUTP biosynthetic process

Inferred from electronic annotation. Source: InterPro

pyrimidine ribonucleotide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functiondCTP deaminase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 193193Deoxycytidine triphosphate deaminase HAMAP-Rule MF_00146
PRO_0000155969

Sequences

Sequence LengthMass (Da)Tools
P57209 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: DE7DD7FD961FC9FA

FASTA19321,952
        10         20         30         40         50         60 
MRLCDKDIEE WLERKELIIE PYPNKTLING ITVDIHLGNK FRFFYEHTGS CIDLSNSKII 

        70         80         90        100        110        120 
GGLSLTEIMS NEIIFSKEQP CFLQPGSLVL CSTFESIKMP NNLVGWLDGR SSLARLGLMI 

       130        140        150        160        170        180 
HATAHRIDPG WNGNIVLEMF NAGKLTLVLR PKMRIAALSF EVLSQPVLRP YNLRKEAKYK 

       190 
IQNGVVPSRI HKE 

« Hide

References

[1]"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: APS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000003 Genomic DNA. Translation: BAB12827.1. Different initiation.
RefSeqNP_239941.2. NC_002528.1.

3D structure databases

ProteinModelPortalP57209.
SMRP57209. Positions 1-193.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB12827; BAB12827; BAB12827.
GeneID1109553.
KEGGbuc:BU108.
PATRIC21243726. VBIBucAph127364_0116.

Phylogenomic databases

eggNOGCOG0717.
HOGENOMHOG000228601.
KOK01494.
OMANFHRTEI.
OrthoDBEOG67DPKR.

Enzyme and pathway databases

BioCycBAPH107806:GBZJ-108-MONOMER.
UniPathwayUPA00610; UER00665.

Family and domain databases

Gene3D2.70.40.10. 1 hit.
HAMAPMF_00146. dCTP_deaminase.
InterProIPR011962. dCTP_deam.
IPR029054. dUTPase-like.
IPR008180. dUTPase/dCTP_deaminase.
[Graphical view]
PfamPF00692. dUTPase. 1 hit.
[Graphical view]
SUPFAMSSF51283. SSF51283. 1 hit.
TIGRFAMsTIGR02274. dCTP_deam. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDCD_BUCAI
AccessionPrimary (citable) accession number: P57209
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: June 11, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Buchnera aphidicola (subsp. Acyrthosiphon pisum)

Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names