P57162 (CYSE_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Serine acetyltransferase
Short name=SAT
EC=2.3.1.30

Gene names

Name:	cysE
Ordered Locus Names:	BU054

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)

Taxonomic identifier

107806 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Acetyl-CoA + L-serine = CoA + O-acetyl-L-serine.
Pathway	Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the transferase hexapeptide repeat family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis
Cellular component	Cytoplasm
Domain	Repeat
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	serine O-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 274	274	Serine acetyltransferase		PRO_0000068666

Sequences

	Sequence		Length	Mass (Da)
	P57162 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 553D252F1048B6B1	FASTA	274	30,165
	10 20 30 40 50 60 MCILKISRIW NKILYDVSFL LKKEPILSDF YQSSILQHQS FTSSLSYILS NKLSTSMISE 70 80 90 100 110 120 KKIQGIFDDV YLNDRSILNF IVQDIKAVLK RDPAVNDYLT PLLYLKGFHA LEAYRISHYL 130 140 150 160 170 180 WNTGKKSLSL YLQSRISSEF SVDIHPAAFI GSGVMLDHAT GIVIGEGVTI ENDVSILHSV 190 200 210 220 230 240 TLGGTGKNFS QNRHPTIRKG VVIGAGAKIL GNIEVGSGAK IGAGSIVLKN VPSDVTVVGV 250 260 270 PAKIVSQVSS KKYYSQKKKN SLKYINIFQH GDGI

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: APS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000003 Genomic DNA. Translation: BAB12777.1.
RefSeq	NP_239891.1. NC_002528.1.
3D structure databases
ProteinModelPortal	P57162.
SMR	P57162. Positions 8-245.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000003324; EBBUCP00000003100; EBBUCG00000003324.
GeneID	1109461.
GenomeReviews	Gene locus BU054 in contig BA000003_GR.
KEGG	buc:BU054.
PATRIC	21243614. VBIBucAph127364_0063.
Phylogenomic databases
GeneTree	EBGT00050000007964.
HOGENOM	HBG754554.
OMA	DLCLSAF.
PhylomeDB	P57162.
ProtClustDB	CLSK315065.
Enzyme and pathway databases
BioCyc	BSP107806:BU054-MONOMER.
Family and domain databases
InterPro	IPR001451. Hexapep_transf. IPR018357. Hexapep_transf_CS. IPR010493. Ser_AcTrfase_N. IPR005881. Ser_O-AcTrfase. IPR011004. Trimer_LpxA-like. [Graphical view]
KO	K00640.
Pfam	PF00132. Hexapep. 1 hit. PF06426. SATase_N. 1 hit. [Graphical view]
SMART	SM00971. SATase_N. 1 hit. [Graphical view]
SUPFAM	SSF51161. Trimer_LpxA_like. 1 hit.
TIGRFAMs	TIGR01172. CysE. 1 hit.
PROSITE	PS00101. HEXAPEP_TRANSFERASES. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CYSE_BUCAI

Accession

Primary (citable) accession number: P57162

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	January 25, 2012
This is version 63 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program