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P57156

- ARGC_BUCAI

UniProt

P57156 - ARGC_BUCAI

Protein

N-acetyl-gamma-glutamyl-phosphate reductase

Gene

argC

Organism
Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Dec 2000)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei154 – 1541By similarity

    GO - Molecular functioni

    1. N-acetyl-gamma-glutamyl-phosphate reductase activity Source: UniProtKB-HAMAP
    2. NAD binding Source: InterPro

    GO - Biological processi

    1. arginine biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Amino-acid biosynthesis, Arginine biosynthesis

    Keywords - Ligandi

    NADP

    Enzyme and pathway databases

    BioCyciBAPH107806:GBZJ-48-MONOMER.
    UniPathwayiUPA00068; UER00108.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    N-acetyl-gamma-glutamyl-phosphate reductase (EC:1.2.1.38)
    Short name:
    AGPR
    Alternative name(s):
    N-acetyl-glutamate semialdehyde dehydrogenase
    Short name:
    NAGSA dehydrogenase
    Gene namesi
    Name:argC
    Ordered Locus Names:BU048
    OrganismiBuchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
    Taxonomic identifieri107806 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeBuchnera
    ProteomesiUP000001806: Chromosome

    Subcellular locationi

    Cytoplasm By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 334334N-acetyl-gamma-glutamyl-phosphate reductasePRO_0000112391Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP57156.
    SMRiP57156. Positions 1-334.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0002.
    HOGENOMiHOG000254902.
    KOiK00145.
    OMAiNHRHHPE.
    OrthoDBiEOG6XSZS3.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_00150. ArgC_type1.
    InterProiIPR023013. AGPR_AS.
    IPR000706. AGPR_type-1.
    IPR016040. NAD(P)-bd_dom.
    IPR000534. Semialdehyde_DH_NAD-bd.
    IPR012280. Semialdhyde_DH_dimer_dom.
    [Graphical view]
    PfamiPF01118. Semialdhyde_dh. 1 hit.
    PF02774. Semialdhyde_dhC. 1 hit.
    [Graphical view]
    SMARTiSM00859. Semialdhyde_dh. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01850. argC. 1 hit.
    PROSITEiPS01224. ARGC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P57156-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLNVVIVGAS GYAGAELVNY MHRHRFANIK KIFVSKNSLN IDKLFSDVHQ    50
    QFKNIVDLRF DTIRNCTLIK KNIDAVFLAT DHRVSHSLVP FFLSSNCIVF 100
    DLSASYRMNN KKVYLDYYGF VHEYEELLKN SVYGLAEWEQ EKIKKANLIA 150
    LPGCYATCIQ LALKPLIKEN VLCDKNIPII NAISGVSGAG RKASLNNSFC 200
    EVSLQPYNIF THRHTPEIIE KLGVPVIFIP HLGPFSRGII ATITCKLKPN 250
    VKSIDIHNIF NKFYKNKPLI RIYKKYLPSI KSVEKQPFCD IGFVIKDDYI 300
    VIVAAEDNLL KGAAAQAVQC FNVRFGFSET ESII 334
    Length:334
    Mass (Da):37,815
    Last modified:December 1, 2000 - v1
    Checksum:i1032E60048AFA90A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB12771.1.
    RefSeqiNP_239885.1. NC_002528.1.

    Genome annotation databases

    EnsemblBacteriaiBAB12771; BAB12771; BAB12771.
    GeneIDi1109455.
    KEGGibuc:BU048.
    PATRICi21243602. VBIBucAph127364_0057.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BA000003 Genomic DNA. Translation: BAB12771.1 .
    RefSeqi NP_239885.1. NC_002528.1.

    3D structure databases

    ProteinModelPortali P57156.
    SMRi P57156. Positions 1-334.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai BAB12771 ; BAB12771 ; BAB12771 .
    GeneIDi 1109455.
    KEGGi buc:BU048.
    PATRICi 21243602. VBIBucAph127364_0057.

    Phylogenomic databases

    eggNOGi COG0002.
    HOGENOMi HOG000254902.
    KOi K00145.
    OMAi NHRHHPE.
    OrthoDBi EOG6XSZS3.

    Enzyme and pathway databases

    UniPathwayi UPA00068 ; UER00108 .
    BioCyci BAPH107806:GBZJ-48-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_00150. ArgC_type1.
    InterProi IPR023013. AGPR_AS.
    IPR000706. AGPR_type-1.
    IPR016040. NAD(P)-bd_dom.
    IPR000534. Semialdehyde_DH_NAD-bd.
    IPR012280. Semialdhyde_DH_dimer_dom.
    [Graphical view ]
    Pfami PF01118. Semialdhyde_dh. 1 hit.
    PF02774. Semialdhyde_dhC. 1 hit.
    [Graphical view ]
    SMARTi SM00859. Semialdhyde_dh. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01850. argC. 1 hit.
    PROSITEi PS01224. ARGC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS."
      Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.
      Nature 407:81-86(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: APS.

    Entry informationi

    Entry nameiARGC_BUCAI
    AccessioniPrimary (citable) accession number: P57156
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: December 1, 2000
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Buchnera aphidicola (subsp. Acyrthosiphon pisum)
      Buchnera aphidicola (subsp. Acyrthosiphon pisum): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3