Reviewed, UniProtKB/Swiss-Prot P57144 (DBH_BUCAI)

Names and origin

Protein names

Recommended name:
    DNA-binding protein HU

Gene names

Name:	hup
Ordered Locus Names:	BU032

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	92 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the bacterial histone-like protein family.

Ontologies

Keywords
Biological process	DNA condensation
Ligand	DNA-binding
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	chromosome condensation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 92	92	DNA-binding protein HU		PRO_0000104924

Sequences

	Sequence		Length	Mass (Da)
	P57144-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 998475DABE888118	FASTA	92	10,044
	10 20 30 40 50 60 MNKTQLINVI SKKSNLSKIQ AKLTLETTLS TIIDSLKKGE SVQIVGFGTF KVNLRSSRTG 70 80 90 RNPQTGKEIQ IPATKVPSFT SGKTLKNAIK QL

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000003 Genomic DNA. Translation: BAB12759.1.
RefSeq	NP_239873.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1109540.
GenomeReviews	Gene locus BU032 in contig BA000003_GR.
KEGG	buc:BU032.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	P57144.
OMA	MNSITYE
Enzyme and pathway databases
BioCyc	BSP107806:BU032-MON.
Family and domain databases
InterPro	IPR000119. Hist_DNA_bd_bac. IPR020816. Histone-like_DNA_bd_CS. IPR010992. IHF-like_DNA_bd. [Graphical view]
Gene3D	G3DSA:4.10.520.10. Hist_DNA_bd_bac. 1 hit.
Pfam	PF00216. Bac_DNA_binding. 1 hit. [Graphical view]
PRINTS	PR01727. DNABINDINGHU.
SMART	SM00411. BHL. 1 hit. [Graphical view]
PROSITE	PS00045. HISTONE_LIKE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DBH_BUCAI

Accession

Primary (citable) accession number: P57144

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	November 24, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)