P57133 (EFP_BUCAI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Elongation factor P
Short name=EF-P

Gene names

Name:	efp
Ordered Locus Names:	BU020

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)

Taxonomic identifier

107806 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	189 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase By similarity. HAMAP MF_00141
Pathway	Protein biosynthesis; polypeptide chain elongation. HAMAP MF_00141
Sequence similarities	Belongs to the elongation factor P family.
Sequence caution	The sequence BAB12747.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	peptide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Elongation factor P HAMAP MF_00141		PRO_0000094215

Sequences

	Sequence		Length	Mass (Da)
	P57133 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: B676EBE1497595A1	FASTA	189	21,721
	10 20 30 40 50 60 MRIYHSNNFR SGRKIIFENE PCLIESSEFV KPGKGQSFVR VKLRKLLTKQ LIEKTFKSTD 70 80 90 100 110 120 SLEIADIIEY TLSYLYNDGR FWYFINNNTF EELSVDEKII GVHKKWLLEQ DTCIVTLWNN 130 140 150 160 170 180 QPISITPNNF VNLKVIHVQA TLKGDTINTS STKLATLSTG AIVRVPLFIQ VGSLIKVDTR SGEYVSRIK

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: APS.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000003 Genomic DNA. Translation: BAB12747.1. Different initiation.
RefSeq	NP_239861.1. NC_002528.1.
3D structure databases
ProteinModelPortal	P57133.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBUCT00000003279; EBBUCP00000003055; EBBUCG00000003279.
GeneID	1109528.
GenomeReviews	Gene locus BU020 in contig BA000003_GR.
KEGG	buc:BU020.
PATRIC	21243544. VBIBucAph127364_0032.
Phylogenomic databases
GeneTree	EBGT00050000008046.
HOGENOM	HBG303311.
OMA	MISSNDF.
PhylomeDB	P57133.
ProtClustDB	PRK00529.
Enzyme and pathway databases
BioCyc	BSP107806:BU020-MONOMER.
Family and domain databases
HAMAP	MF_00141. EF-P. [Tree]
InterPro	IPR015365. Elong-fact-P_C. IPR012340. NA-bd_OB-fold. IPR016027. NA-bd_OB-fold-like. IPR020599. Transl_elong_fac_P/YeiP. IPR013185. Transl_elong_KOW-like. IPR001059. Transl_elong_P/YeiP_cen. IPR013852. Transl_elong_P/YeiP_CS. IPR011768. Transl_elongation_fac_P. IPR014722. Transl_SH3-like_sub. IPR008991. Translation_prot_SH3-like. [Graphical view]
Gene3D	G3DSA:2.40.50.140. OB_NA_bd_sub. 2 hits. G3DSA:2.30.30.30. Ribosomal_L2. 1 hit.
KO	K02356.
Pfam	PF01132. EFP. 1 hit. PF08207. EFP_N. 1 hit. PF09285. Elong-fact-P_C. 1 hit. [Graphical view]
PIRSF	PIRSF005901. EF-P. 1 hit.
SMART	SM00841. Elong-fact-P_C. 1 hit. [Graphical view]
SUPFAM	SSF50249. Nucleic_acid_OB. 2 hits. SSF50104. Transl_SH3_like. 1 hit.
TIGRFAMs	TIGR00038. Efp. 1 hit.
PROSITE	PS01275. EFP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EFP_BUCAI

Accession

Primary (citable) accession number: P57133

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	January 25, 2012
This is version 58 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program