Reviewed, UniProtKB/Swiss-Prot P57131 (OXAA_BUCAI)

Names and origin

Protein names

Recommended name:
    Membrane protein oxaA

Gene names

Name:	oxaA
Ordered Locus Names:	BU015

Organism

Buchnera aphidicola subsp. Acyrthosiphon pisum (Acyrthosiphon pisum symbiotic bacterium) [Complete proteome] [HAMAP]

Taxonomic identifier

118099 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera

Protein attributes

Sequence length	532 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Required for the insertion of integral membrane proteins into the membrane. Probably plays an essential role in the integration of proteins of the respiratory chain complexes. Involved in integration of membrane proteins that insert dependently and independently of the Sec translocase complex By similarity.
Subunit structure	Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration By similarity.
Subcellular location	Cell membrane; Multi-pass membrane protein By similarity.
Sequence similarities	Belongs to the OXA1/oxaA family. Type 1 subfamily.

Ontologies

Keywords
Cellular component	Cell membrane Membrane
Domain	Transmembrane
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	protein insertion into membrane Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 532	532	Membrane protein oxaA HAMAP MF_01810		PRO_0000124696
Regions
	Transmembrane	7 – 24	18	Potential
	Transmembrane	335 – 357	23	Potential
	Transmembrane	412 – 434	23	Potential
	Transmembrane	490 – 512	23	Potential

Sequences

	Sequence		Length	Mass (Da)
	P57131-1 [UniParc]. Last modified December 1, 2000. Version 1. Checksum: 0A234563EFBEF9CE	FASTA	532	61,906
	10 20 30 40 50 60 MEVQRNFFIF AFLFVSFLLW QAWQSQMFLN KKTNEKIDPI FHFIDVKKNK KKIFIKNDVI 70 80 90 100 110 120 SLVVNMYGGD VEEASLLAYK DTLYSSRPFK LLETGSDFIY QAQSGLIGKD GPDSSINDSR 130 140 150 160 170 180 PLYSANKNFF VLGPNEKELR VPIKWLSKNG VIYKKTFILK PNRYDVQIEY DVYNPSKESL 190 200 210 220 230 240 NMNIFGQIKQ TINLPKKRNV YSGNFALQTF RGAAYSSDDN KYEKYKFDMI ANNKNLHIMT 250 260 270 280 290 300 ESGWIAMLQQ YFAVAWIPDN LGKNTIYTSS LDHDTAVIGY KSPIINIPPN SRSIIKSKLW 310 320 330 340 350 360 IGPKIQKEMK LVAPNLDLTV DYGWLWFLSQ PLFKLLTILY SIIGNWGFSI ILITFIMRGL 370 380 390 400 410 420 TYPLTKAQYI SMAKMRALQP KIQEIKEKFS KDKQRISQEM ILLYKKEKIN PLGGFLPIFI 430 440 450 460 470 480 QMPIFLSLYY MLIGSVELRH APFLLWIHDL SSQDPYYVLP VIMGLTMFFI QKISSTNHIS 490 500 510 520 530 DPLQKKIMNF MPVIFTAFFL WFPSGLVLYY IISNLVTIIQ QKFILSNLEK NR

References

[1]	"Genome sequence of the endocellular bacterial symbiont of aphids Buchnera sp. APS." Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H. Nature 407:81-86(2000) [PubMed: 10993077] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tokyo 1998.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000003 Genomic DNA. Translation: BAB12743.1.
RefSeq	NP_239857.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1109524.
GenomeReviews	Gene locus BU015 in contig BA000003_GR.
KEGG	buc:BU015.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG507812.
OMA	LHIMTES.
Enzyme and pathway databases
BioCyc	BSP107806:BU015-MON.
Family and domain databases
HAMAP	MF_01810. [Tree]
InterPro	IPR020001. Membrane_insert_OxaA/YidC_core. IPR001708. Membrane_insertion_OxaA/YidC. IPR013308. Membrane_insertion_YidC. IPR019998. Membrane_insertion_YidC/OxoA_N. [Graphical view]
PANTHER	PTHR12428. Innermemb_insert. 1 hit.
Pfam	PF02096. 60KD_IMP. 1 hit. [Graphical view]
PRINTS	PR00701. 60KDINNERMP. PR01900. YIDCPROTEIN.
ProtoNet	Search...

Entry information

Entry name

OXAA_BUCAI

Accession

Primary (citable) accession number: P57131

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	December 1, 2000
Last modified:	December 15, 2009
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)