SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P57103

- NAC3_HUMAN

UniProt

P57103 - NAC3_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Sodium/calcium exchanger 3
Gene
SLC8A3, NCX3
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Rapidly transports Ca2+ during excitation-contraction coupling. Ca2+ is extruded from the cell during relaxation so as to prevent overloading of intracellular stores By similarity.

Enzyme regulationi

By intracellular calcium ions By similarity.

GO - Molecular functioni

  1. calcium:sodium antiporter activity Source: Ensembl

GO - Biological processi

  1. blood coagulation Source: Reactome
  2. calcium ion export from cell Source: Ensembl
  3. calcium ion import into cell Source: Ensembl
  4. calcium ion transport into cytosol Source: Ensembl
  5. cell communication Source: InterPro
  6. cellular response to cAMP Source: Ensembl
  7. ion transport Source: Reactome
  8. telencephalon development Source: Ensembl
  9. transmembrane transport Source: Reactome
Complete GO annotation...

Keywords - Biological processi

Antiport, Calcium transport, Ion transport, Sodium transport, Transport

Keywords - Ligandi

Calcium, Calmodulin-binding, Sodium

Enzyme and pathway databases

ReactomeiREACT_19320. Sodium/Calcium exchangers.
REACT_23765. Reduction of cytosolic Ca++ levels.

Protein family/group databases

TCDBi2.A.19.3.3. the ca(2+):cation antiporter (caca) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/calcium exchanger 3
Alternative name(s):
Na(+)/Ca(2+)-exchange protein 3
Solute carrier family 8 member 3
Gene namesi
Name:SLC8A3
Synonyms:NCX3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 14

Organism-specific databases

HGNCiHGNC:11070. SLC8A3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini31 – 7343Extracellular Reviewed prediction
Add
BLAST
Transmembranei74 – 9421Helical; Reviewed prediction
Add
BLAST
Topological domaini95 – 14753Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei148 – 16821Helical; Reviewed prediction
Add
BLAST
Topological domaini169 – 1691Extracellular Reviewed prediction
Transmembranei170 – 19021Helical; Reviewed prediction
Add
BLAST
Topological domaini191 – 20212Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei203 – 22321Helical; Reviewed prediction
Add
BLAST
Topological domaini224 – 2307Extracellular Reviewed prediction
Transmembranei231 – 25121Helical; Reviewed prediction
Add
BLAST
Topological domaini252 – 726475Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei727 – 74721Helical; Reviewed prediction
Add
BLAST
Topological domaini748 – 7547Extracellular Reviewed prediction
Transmembranei755 – 77521Helical; Reviewed prediction
Add
BLAST
Topological domaini776 – 7783Cytoplasmic Reviewed prediction
Transmembranei779 – 79921Helical; Reviewed prediction
Add
BLAST
Topological domaini800 – 82829Extracellular Reviewed prediction
Add
BLAST
Transmembranei829 – 84921Helical; Reviewed prediction
Add
BLAST
Topological domaini850 – 86011Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei861 – 88121Helical; Reviewed prediction
Add
BLAST
Topological domaini882 – 90322Extracellular Reviewed prediction
Add
BLAST
Transmembranei904 – 92421Helical; Reviewed prediction
Add
BLAST
Topological domaini925 – 9273Cytoplasmic Reviewed prediction

GO - Cellular componenti

  1. dendritic spine Source: Ensembl
  2. integral component of membrane Source: UniProtKB-KW
  3. microtubule Source: Ensembl
  4. mitochondrion Source: Ensembl
  5. neuronal cell body Source: Ensembl
  6. plasma membrane Source: Reactome
  7. sarcolemma Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA315.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3030 Reviewed prediction
Add
BLAST
Chaini31 – 927897Sodium/calcium exchanger 3
PRO_0000019384Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi45 – 451N-linked (GlcNAc...) Reviewed prediction
Glycosylationi823 – 8231N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiP57103.
PRIDEiP57103.

PTM databases

PhosphoSiteiP57103.

Expressioni

Tissue specificityi

Isoform 2 is expressed in brain and skeletal muscle. Isoform 3 is expressed in excitable cells of brain, retina and skeletal muscle. Isoform 4 is expressed in skeletal muscle.1 Publication

Gene expression databases

ArrayExpressiP57103.
BgeeiP57103.
CleanExiHS_SLC8A3.
GenevestigatoriP57103.

Organism-specific databases

HPAiHPA001669.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000370669.

Structurei

3D structure databases

ProteinModelPortaliP57103.
SMRiP57103. Positions 395-681, 758-872.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati140 – 18041Alpha-1
Add
BLAST
Domaini386 – 485100Calx-beta 1
Add
BLAST
Domaini519 – 619101Calx-beta 2
Add
BLAST
Repeati796 – 83237Alpha-2
Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni253 – 27220Calmodulin-binding By similarity
Add
BLAST

Sequence similaritiesi

Contains 2 Calx-beta domains.

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG241889.
HOGENOMiHOG000266971.
HOVERGENiHBG006441.
InParanoidiP57103.
KOiK05849.
OMAiCGHGFIA.
OrthoDBiEOG7S4X56.
PhylomeDBiP57103.
TreeFamiTF314308.

Family and domain databases

InterProiIPR003644. Calx_beta.
IPR004836. Na_Ca_Ex.
IPR004837. NaCa_Exmemb.
[Graphical view]
PfamiPF03160. Calx-beta. 2 hits.
PF01699. Na_Ca_ex. 2 hits.
[Graphical view]
PRINTSiPR01259. NACAEXCHNGR.
SMARTiSM00237. Calx_beta. 2 hits.
[Graphical view]
TIGRFAMsiTIGR00845. caca. 1 hit.

Sequences (7)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 7 isoformsi produced by alternative splicing. Align

Isoform 3 (identifier: P57103-1) [UniParc]FASTAAdd to Basket

Also known as: NCX3.3

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MAWLRLQPLT SAFLHFGLVT FVLFLNGLRA EAGGSGDVPS TGQNNESCSG    50
SSDCKEGVIL PIWYPENPSL GDKIARVIVY FVALIYMFLG VSIIADRFMA 100
SIEVITSQER EVTIKKPNGE TSTTTIRVWN ETVSNLTLMA LGSSAPEILL 150
SLIEVCGHGF IAGDLGPSTI VGSAAFNMFI IIGICVYVIP DGETRKIKHL 200
RVFFITAAWS IFAYIWLYMI LAVFSPGVVQ VWEGLLTLFF FPVCVLLAWV 250
ADKRLLFYKY MHKKYRTDKH RGIIIETEGD HPKGIEMDGK MMNSHFLDGN 300
LVPLEGKEVD ESRREMIRIL KDLKQKHPEK DLDQLVEMAN YYALSHQQKS 350
RAFYRIQATR MMTGAGNILK KHAAEQAKKA SSMSEVHTDE PEDFISKVFF 400
DPCSYQCLEN CGAVLLTVVR KGGDMSKTMY VDYKTEDGSA NAGADYEFTE 450
GTVVLKPGET QKEFSVGIID DDIFEEDEHF FVRLSNVRIE EEQPEEGMPP 500
AIFNSLPLPR AVLASPCVAT VTILDDDHAG IFTFECDTIH VSESIGVMEV 550
KVLRTSGARG TVIVPFRTVE GTAKGGGEDF EDTYGELEFK NDETVKTIRV 600
KIVDEEEYER QENFFIALGE PKWMERGISA LLLSPDVTDR KLTMEEEEAK 650
RIAEMGKPVL GEHPKLEVII EESYEFKTTV DKLIKKTNLA LVVGTHSWRD 700
QFMEAITVSA AGDEDEDESG EERLPSCFDY VMHFLTVFWK VLFACVPPTE 750
YCHGWACFAV SILIIGMLTA IIGDLASHFG CTIGLKDSVT AVVFVAFGTS 800
VPDTFASKAA ALQDVYADAS IGNVTGSNAV NVFLGIGLAW SVAAIYWALQ 850
GQEFHVSAGT LAFSVTLFTI FAFVCISVLL YRRRPHLGGE LGGPRGCKLA 900
TTWLFVSLWL LYILFATLEA YCYIKGF 927
Length:927
Mass (Da):103,010
Last modified:August 29, 2003 - v2
Checksum:i7B43CB6A9D77615E
GO
Isoform 2 (identifier: P57103-2) [UniParc]FASTAAdd to Basket

Also known as: NCX3.2

The sequence of this isoform differs from the canonical sequence as follows:
     630-635: Missing.

Show »
Length:921
Mass (Da):102,415
Checksum:i9E7E932E8EAE13F7
GO
Isoform 4 (identifier: P57103-3) [UniParc]FASTAAdd to Basket

Also known as: NCX3.4

The sequence of this isoform differs from the canonical sequence as follows:
     596-620: KTIRVKIVDEEEYERQENFFIALGE → CDRQEADYGRRGGQEDSRDGKASIG
     621-927: Missing.

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available.

Show »
Length:620
Mass (Da):68,947
Checksum:i0FBEC381D196FD7C
GO
Isoform 5 (identifier: P57103-4) [UniParc]FASTAAdd to Basket

Also known as: NCX3-tN.1

The sequence of this isoform differs from the canonical sequence as follows:
     1-643: Missing.

Note: Expressed in fetal brain.

Show »
Length:284
Mass (Da):31,142
Checksum:i14B4A98B3DE17144
GO
Isoform 6 (identifier: P57103-5) [UniParc]FASTAAdd to Basket

Also known as: NCX3-tN.2

The sequence of this isoform differs from the canonical sequence as follows:
     1-623: Missing.
     630-635: Missing.

Note: Expressed in fetal brain.

Show »
Length:298
Mass (Da):32,745
Checksum:i6B91455189B786D7
GO
Isoform 7 (identifier: P57103-6) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     636-638: Missing.

Show »
Length:924
Mass (Da):102,694
Checksum:iA0A556B753998A07
GO
Isoform 8 (identifier: P57103-7) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     599-638: RVKIVDEEEY...SALLLSPDVT → HIKVIDDEAY...SFQKALLLSP

Show »
Length:925
Mass (Da):102,804
Checksum:i0CCF8DA0881C4FDA
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti612 – 6121E → Q in a breast cancer sample; somatic mutation. 1 Publication
VAR_036463

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 643643Missing in isoform 5.
VSP_043125Add
BLAST
Alternative sequencei1 – 623623Missing in isoform 6.
VSP_043126Add
BLAST
Alternative sequencei596 – 62025KTIRV…IALGE → CDRQEADYGRRGGQEDSRDG KASIG in isoform 4.
VSP_008117Add
BLAST
Alternative sequencei599 – 63840RVKIV…SPDVT → HIKVIDDEAYEKNKNYFIEM MGPRMVDMSFQKALLLSP in isoform 8.
VSP_044502Add
BLAST
Alternative sequencei621 – 927307Missing in isoform 4.
VSP_008118Add
BLAST
Alternative sequencei630 – 6356Missing in isoform 2 and isoform 6.
VSP_008116
Alternative sequencei636 – 6383Missing in isoform 7.
VSP_043850

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF510501 mRNA. Translation: AAN60790.1.
AF510502 mRNA. Translation: AAN60791.1.
AF510503 mRNA. Translation: AAN60792.1.
AF508982 Genomic DNA. Translation: AAM90955.1.
AJ304852 mRNA. Translation: CAC40984.1.
AJ304853 mRNA. Translation: CAC40985.1.
AJ745101 mRNA. Translation: CAG33739.1.
AJ745102 mRNA. Translation: CAG33740.1.
AL135747 Genomic DNA. No translation available.
AL160191 Genomic DNA. No translation available.
CH471061 Genomic DNA. Translation: EAW81019.1.
CH471061 Genomic DNA. Translation: EAW81021.1.
CH471061 Genomic DNA. Translation: EAW81026.1.
BC142969 mRNA. Translation: AAI42970.1.
X93017 Genomic DNA. No translation available.
CCDSiCCDS35498.1. [P57103-1]
CCDS41967.1. [P57103-4]
CCDS45131.1. [P57103-5]
CCDS53904.1. [P57103-6]
CCDS9799.1. [P57103-7]
CCDS9800.1. [P57103-2]
RefSeqiNP_001123889.1. NM_001130417.2. [P57103-5]
NP_150287.1. NM_033262.4. [P57103-7]
NP_489479.1. NM_058240.3. [P57103-6]
NP_891977.1. NM_182932.2. [P57103-2]
NP_891981.1. NM_182936.2. [P57103-4]
NP_892114.1. NM_183002.2. [P57103-1]
UniGeneiHs.337696.

Genome annotation databases

EnsembliENST00000216568; ENSP00000216568; ENSG00000100678. [P57103-5]
ENST00000356921; ENSP00000349392; ENSG00000100678. [P57103-2]
ENST00000357887; ENSP00000350560; ENSG00000100678. [P57103-7]
ENST00000381269; ENSP00000370669; ENSG00000100678. [P57103-1]
ENST00000394330; ENSP00000377863; ENSG00000100678. [P57103-4]
ENST00000494208; ENSP00000436332; ENSG00000100678. [P57103-3]
ENST00000528359; ENSP00000433531; ENSG00000100678. [P57103-7]
ENST00000534137; ENSP00000436688; ENSG00000100678. [P57103-6]
GeneIDi6547.
KEGGihsa:6547.
UCSCiuc001xlu.3. human. [P57103-4]
uc001xlv.3. human. [P57103-5]
uc001xlw.3. human. [P57103-6]
uc001xlx.3. human. [P57103-7]
uc001xly.3. human. [P57103-1]
uc001xlz.3. human. [P57103-2]

Polymorphism databases

DMDMi34395973.

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF510501 mRNA. Translation: AAN60790.1 .
AF510502 mRNA. Translation: AAN60791.1 .
AF510503 mRNA. Translation: AAN60792.1 .
AF508982 Genomic DNA. Translation: AAM90955.1 .
AJ304852 mRNA. Translation: CAC40984.1 .
AJ304853 mRNA. Translation: CAC40985.1 .
AJ745101 mRNA. Translation: CAG33739.1 .
AJ745102 mRNA. Translation: CAG33740.1 .
AL135747 Genomic DNA. No translation available.
AL160191 Genomic DNA. No translation available.
CH471061 Genomic DNA. Translation: EAW81019.1 .
CH471061 Genomic DNA. Translation: EAW81021.1 .
CH471061 Genomic DNA. Translation: EAW81026.1 .
BC142969 mRNA. Translation: AAI42970.1 .
X93017 Genomic DNA. No translation available.
CCDSi CCDS35498.1. [P57103-1 ]
CCDS41967.1. [P57103-4 ]
CCDS45131.1. [P57103-5 ]
CCDS53904.1. [P57103-6 ]
CCDS9799.1. [P57103-7 ]
CCDS9800.1. [P57103-2 ]
RefSeqi NP_001123889.1. NM_001130417.2. [P57103-5 ]
NP_150287.1. NM_033262.4. [P57103-7 ]
NP_489479.1. NM_058240.3. [P57103-6 ]
NP_891977.1. NM_182932.2. [P57103-2 ]
NP_891981.1. NM_182936.2. [P57103-4 ]
NP_892114.1. NM_183002.2. [P57103-1 ]
UniGenei Hs.337696.

3D structure databases

ProteinModelPortali P57103.
SMRi P57103. Positions 395-681, 758-872.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000370669.

Protein family/group databases

TCDBi 2.A.19.3.3. the ca(2+):cation antiporter (caca) family.

PTM databases

PhosphoSitei P57103.

Polymorphism databases

DMDMi 34395973.

Proteomic databases

PaxDbi P57103.
PRIDEi P57103.

Protocols and materials databases

DNASUi 6547.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000216568 ; ENSP00000216568 ; ENSG00000100678 . [P57103-5 ]
ENST00000356921 ; ENSP00000349392 ; ENSG00000100678 . [P57103-2 ]
ENST00000357887 ; ENSP00000350560 ; ENSG00000100678 . [P57103-7 ]
ENST00000381269 ; ENSP00000370669 ; ENSG00000100678 . [P57103-1 ]
ENST00000394330 ; ENSP00000377863 ; ENSG00000100678 . [P57103-4 ]
ENST00000494208 ; ENSP00000436332 ; ENSG00000100678 . [P57103-3 ]
ENST00000528359 ; ENSP00000433531 ; ENSG00000100678 . [P57103-7 ]
ENST00000534137 ; ENSP00000436688 ; ENSG00000100678 . [P57103-6 ]
GeneIDi 6547.
KEGGi hsa:6547.
UCSCi uc001xlu.3. human. [P57103-4 ]
uc001xlv.3. human. [P57103-5 ]
uc001xlw.3. human. [P57103-6 ]
uc001xlx.3. human. [P57103-7 ]
uc001xly.3. human. [P57103-1 ]
uc001xlz.3. human. [P57103-2 ]

Organism-specific databases

CTDi 6547.
GeneCardsi GC14M070510.
HGNCi HGNC:11070. SLC8A3.
HPAi HPA001669.
MIMi 607991. gene.
neXtProti NX_P57103.
PharmGKBi PA315.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG241889.
HOGENOMi HOG000266971.
HOVERGENi HBG006441.
InParanoidi P57103.
KOi K05849.
OMAi CGHGFIA.
OrthoDBi EOG7S4X56.
PhylomeDBi P57103.
TreeFami TF314308.

Enzyme and pathway databases

Reactomei REACT_19320. Sodium/Calcium exchangers.
REACT_23765. Reduction of cytosolic Ca++ levels.

Miscellaneous databases

ChiTaRSi SLC8A3. human.
GenomeRNAii 6547.
NextBioi 25473.
PROi P57103.
SOURCEi Search...

Gene expression databases

ArrayExpressi P57103.
Bgeei P57103.
CleanExi HS_SLC8A3.
Genevestigatori P57103.

Family and domain databases

InterProi IPR003644. Calx_beta.
IPR004836. Na_Ca_Ex.
IPR004837. NaCa_Exmemb.
[Graphical view ]
Pfami PF03160. Calx-beta. 2 hits.
PF01699. Na_Ca_ex. 2 hits.
[Graphical view ]
PRINTSi PR01259. NACAEXCHNGR.
SMARTi SM00237. Calx_beta. 2 hits.
[Graphical view ]
TIGRFAMsi TIGR00845. caca. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The human SLC8A3 gene and the tissue-specific Na+/Ca2+ exchanger 3 isoforms."
    Gabellini N., Bortoluzzi S., Danieli G.A., Carafoli E.
    Gene 298:1-7(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 2; 3; 4; 7 AND 8).
  2. "Control of the Na+/Ca2+ exchanger 3 promoter by cyclic adenosine monophosphate and Ca2+ in differentiating neurons."
    Gabellini N., Bortoluzzi S., Danieli G.A., Carafoli E.
    J. Neurochem. 84:282-293(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 3).
  3. "Molecular cloning and characterization of two novel truncated isoforms of human Na+/Ca2+ exchanger 3, expressed in fetal brain."
    Lindgren R.M., Zhao J., Heller S., Berglind H., Nister M.
    Gene 348:143-155(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 5 AND 6), TISSUE SPECIFICITY.
    Tissue: Brain.
  4. "The DNA sequence and analysis of human chromosome 14."
    Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H.
    , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
    Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 6).
  7. "The organization of the human gene of the sodium-calcium exchanger."
    Kraev A.S., Chumakov I.M., Carafoli E.
    Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-595.
  8. Cited for: VARIANT [LARGE SCALE ANALYSIS] GLN-612.

Entry informationi

Entry nameiNAC3_HUMAN
AccessioniPrimary (citable) accession number: P57103
Secondary accession number(s): Q5K3P6
, Q5K3P7, Q8IUE9, Q8IUF0, Q8NFI7, Q96QG1, Q96QG2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 29, 2003
Last modified: September 3, 2014
This is version 120 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 14
    Human chromosome 14: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi