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P57086 (SCND1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 115. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
SCAN domain-containing protein 1
Gene names
Name:SCAND1
Synonyms:SDP1
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length179 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

May regulate transcriptional activity.

Subunit structure

Interacts with ZNF202.

Subcellular location

Nucleus Potential.

Sequence similarities

Contains 1 SCAN box domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 179179SCAN domain-containing protein 1
PRO_0000097632

Regions

Domain108 – 16659SCAN box

Sequences

Sequence LengthMass (Da)Tools
P57086 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 88AFEFC8E4DC9796

FASTA17919,082
        10         20         30         40         50         60 
MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP SSPNAAVPEA 

        70         80         90        100        110        120 
IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS RLGPETFRQR FRQFRYQDAA 

       130        140        150        160        170 
GPREAFRQLR ELSRQWLRPD IRTKEQIVEM LVQEQLLAIL PEAARARRIR RRTDVRITG 

« Hide

References

« Hide 'large scale' references
[1]"The SCAN domain mediates selective oligomerization."
Schumacher C., Wang H., Honer C., Ding W., Koehn J., Lawrence Q., Coulis C.M., Wang L.L., Ballinger D., Bowen B.R., Wagner S.
J. Biol. Chem. 275:17173-17179(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
[3]"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. expand/collapse author list , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain and Skin.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AF204271 mRNA. Translation: AAF59839.1.
CR457188 mRNA. Translation: CAG33469.1.
AL109965 Genomic DNA. Translation: CAC09390.1.
CH471077 Genomic DNA. Translation: EAW76150.1.
BC000785 mRNA. Translation: AAH00785.1.
BC036709 mRNA. Translation: AAH36709.1.
BC041022 mRNA. Translation: AAH41022.1.
CCDSCCDS13269.1.
RefSeqNP_057642.1. NM_016558.3.
UniGeneHs.584909.

3D structure databases

ProteinModelPortalP57086.
SMRP57086. Positions 104-162.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid119434. 13 interactions.
IntActP57086. 8 interactions.
MINTMINT-1435996.
STRING9606.ENSP00000301995.

PTM databases

PhosphoSiteP57086.

Polymorphism databases

DMDM10720272.

Proteomic databases

MaxQBP57086.
PaxDbP57086.
PRIDEP57086.

Protocols and materials databases

DNASU51282.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000305978; ENSP00000301995; ENSG00000171222.
ENST00000373991; ENSP00000363103; ENSG00000171222.
GeneID51282.
KEGGhsa:51282.
UCSCuc002xeo.3. human.

Organism-specific databases

CTD51282.
GeneCardsGC20M034542.
HGNCHGNC:10566. SCAND1.
HPACAB034284.
MIM610416. gene.
neXtProtNX_P57086.
PharmGKBPA34979.
GenAtlasSearch...

Phylogenomic databases

eggNOGNOG291024.
HOVERGENHBG079091.
InParanoidP57086.
OMAPERNSAG.
OrthoDBEOG7PS1JD.
PhylomeDBP57086.

Gene expression databases

ArrayExpressP57086.
BgeeP57086.
CleanExHS_SCAND1.
GenevestigatorP57086.

Family and domain databases

InterProIPR027775. C2H2_Znf_fam.
IPR008916. Retrov_capsid_C.
IPR003309. Tscrpt_reg_SCAN.
[Graphical view]
PANTHERPTHR10032. PTHR10032. 1 hit.
PfamPF02023. SCAN. 1 hit.
[Graphical view]
SMARTSM00431. SCAN. 1 hit.
[Graphical view]
SUPFAMSSF47353. SSF47353. 1 hit.
PROSITEPS50804. SCAN_BOX. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSSCAND1. human.
GeneWikiSCAND1.
GenomeRNAi51282.
NextBio54517.
PROP57086.
SOURCESearch...

Entry information

Entry nameSCND1_HUMAN
AccessionPrimary (citable) accession number: P57086
Secondary accession number(s): Q6IAG7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: July 9, 2014
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Human chromosome 20

Human chromosome 20: entries, gene names and cross-references to MIM