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Protein

SCAN domain-containing protein 1

Gene

SCAND1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

May regulate transcriptional activity.

GO - Molecular functioni

Enzyme and pathway databases

SIGNORiP57086.

Names & Taxonomyi

Protein namesi
Recommended name:
SCAN domain-containing protein 1
Gene namesi
Name:SCAND1
Synonyms:SDP1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

HGNCiHGNC:10566. SCAND1.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000171222.
PharmGKBiPA34979.

Polymorphism and mutation databases

BioMutaiSCAND1.
DMDMi10720272.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000976321 – 179SCAN domain-containing protein 1Add BLAST179

Proteomic databases

EPDiP57086.
MaxQBiP57086.
PaxDbiP57086.
PeptideAtlasiP57086.
PRIDEiP57086.

PTM databases

iPTMnetiP57086.
PhosphoSitePlusiP57086.

Expressioni

Gene expression databases

BgeeiENSG00000171222.
CleanExiHS_SCAND1.
GenevisibleiP57086. HS.

Organism-specific databases

HPAiHPA047138.

Interactioni

Subunit structurei

Interacts with ZNF202.

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

BioGridi119434. 25 interactors.
IntActiP57086. 48 interactors.
MINTiMINT-1435996.
STRINGi9606.ENSP00000301995.

Structurei

3D structure databases

ProteinModelPortaliP57086.
SMRiP57086.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini108 – 166SCAN boxPROSITE-ProRule annotationAdd BLAST59

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000110971.
HOVERGENiHBG079091.
InParanoidiP57086.
OMAiTGQRVTP.
OrthoDBiEOG091G16SE.
PhylomeDBiP57086.

Family and domain databases

InterProiView protein in InterPro
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR031262. SCAND1.
PANTHERiPTHR23226:SF87. PTHR23226:SF87. 1 hit.
PfamiView protein in Pfam
PF02023. SCAN. 1 hit.
SMARTiView protein in SMART
SM00431. SCAN. 1 hit.
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiView protein in PROSITE
PS50804. SCAN_BOX. 1 hit.

Sequencei

Sequence statusi: Complete.

P57086-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP
60 70 80 90 100
SSPNAAVPEA IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS
110 120 130 140 150
RLGPETFRQR FRQFRYQDAA GPREAFRQLR ELSRQWLRPD IRTKEQIVEM
160 170
LVQEQLLAIL PEAARARRIR RRTDVRITG
Length:179
Mass (Da):19,082
Last modified:December 1, 2000 - v1
Checksum:i88AFEFC8E4DC9796
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF204271 mRNA. Translation: AAF59839.1.
CR457188 mRNA. Translation: CAG33469.1.
AL109965 Genomic DNA. Translation: CAC09390.1.
CH471077 Genomic DNA. Translation: EAW76150.1.
BC000785 mRNA. Translation: AAH00785.1.
BC036709 mRNA. Translation: AAH36709.1.
BC041022 mRNA. Translation: AAH41022.1.
CCDSiCCDS13269.1.
RefSeqiNP_057642.1. NM_016558.3.
UniGeneiHs.584909.

Genome annotation databases

EnsembliENST00000305978; ENSP00000301995; ENSG00000171222.
ENST00000373991; ENSP00000363103; ENSG00000171222.
ENST00000615116; ENSP00000481289; ENSG00000171222.
GeneIDi51282.
KEGGihsa:51282.
UCSCiuc002xen.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF204271 mRNA. Translation: AAF59839.1.
CR457188 mRNA. Translation: CAG33469.1.
AL109965 Genomic DNA. Translation: CAC09390.1.
CH471077 Genomic DNA. Translation: EAW76150.1.
BC000785 mRNA. Translation: AAH00785.1.
BC036709 mRNA. Translation: AAH36709.1.
BC041022 mRNA. Translation: AAH41022.1.
CCDSiCCDS13269.1.
RefSeqiNP_057642.1. NM_016558.3.
UniGeneiHs.584909.

3D structure databases

ProteinModelPortaliP57086.
SMRiP57086.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119434. 25 interactors.
IntActiP57086. 48 interactors.
MINTiMINT-1435996.
STRINGi9606.ENSP00000301995.

PTM databases

iPTMnetiP57086.
PhosphoSitePlusiP57086.

Polymorphism and mutation databases

BioMutaiSCAND1.
DMDMi10720272.

Proteomic databases

EPDiP57086.
MaxQBiP57086.
PaxDbiP57086.
PeptideAtlasiP57086.
PRIDEiP57086.

Protocols and materials databases

DNASUi51282.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000305978; ENSP00000301995; ENSG00000171222.
ENST00000373991; ENSP00000363103; ENSG00000171222.
ENST00000615116; ENSP00000481289; ENSG00000171222.
GeneIDi51282.
KEGGihsa:51282.
UCSCiuc002xen.3. human.

Organism-specific databases

CTDi51282.
GeneCardsiSCAND1.
HGNCiHGNC:10566. SCAND1.
HPAiHPA047138.
MIMi610416. gene.
neXtProtiNX_P57086.
OpenTargetsiENSG00000171222.
PharmGKBiPA34979.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1721. Eukaryota.
COG5048. LUCA.
GeneTreeiENSGT00730000110971.
HOVERGENiHBG079091.
InParanoidiP57086.
OMAiTGQRVTP.
OrthoDBiEOG091G16SE.
PhylomeDBiP57086.

Enzyme and pathway databases

SIGNORiP57086.

Miscellaneous databases

ChiTaRSiSCAND1. human.
GeneWikiiSCAND1.
GenomeRNAii51282.
PROiP57086.
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000171222.
CleanExiHS_SCAND1.
GenevisibleiP57086. HS.

Family and domain databases

InterProiView protein in InterPro
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR031262. SCAND1.
PANTHERiPTHR23226:SF87. PTHR23226:SF87. 1 hit.
PfamiView protein in Pfam
PF02023. SCAN. 1 hit.
SMARTiView protein in SMART
SM00431. SCAN. 1 hit.
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiView protein in PROSITE
PS50804. SCAN_BOX. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiSCND1_HUMAN
AccessioniPrimary (citable) accession number: P57086
Secondary accession number(s): Q6IAG7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: March 15, 2017
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.