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P57086

- SCND1_HUMAN

UniProt

P57086 - SCND1_HUMAN

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Protein

SCAN domain-containing protein 1

Gene

SCAND1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

May regulate transcriptional activity.

GO - Molecular functioni

  1. identical protein binding Source: UniProtKB
  2. sequence-specific DNA binding RNA polymerase II transcription factor activity Source: RefGenome
  3. sequence-specific DNA binding transcription factor activity Source: UniProtKB
  4. transcription coactivator activity Source: RefGenome

GO - Biological processi

  1. regulation of transcription from RNA polymerase II promoter Source: GOC
  2. transcription from RNA polymerase II promoter Source: GOC
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
SCAN domain-containing protein 1
Gene namesi
Name:SCAND1
Synonyms:SDP1
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 20

Organism-specific databases

HGNCiHGNC:10566. SCAND1.

Subcellular locationi

Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

  1. nucleus Source: LIFEdb
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34979.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 179179SCAN domain-containing protein 1PRO_0000097632Add
BLAST

Proteomic databases

MaxQBiP57086.
PaxDbiP57086.
PRIDEiP57086.

PTM databases

PhosphoSiteiP57086.

Expressioni

Gene expression databases

BgeeiP57086.
CleanExiHS_SCAND1.
ExpressionAtlasiP57086. baseline and differential.
GenevestigatoriP57086.

Organism-specific databases

HPAiCAB034284.

Interactioni

Subunit structurei

Interacts with ZNF202.

Protein-protein interaction databases

BioGridi119434. 15 interactions.
IntActiP57086. 8 interactions.
MINTiMINT-1435996.
STRINGi9606.ENSP00000301995.

Structurei

3D structure databases

ProteinModelPortaliP57086.
SMRiP57086. Positions 104-162.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini108 – 16659SCAN boxPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 SCAN box domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG291024.
GeneTreeiENSGT00730000110971.
HOVERGENiHBG079091.
InParanoidiP57086.
OMAiPERNSAG.
OrthoDBiEOG7PS1JD.
PhylomeDBiP57086.

Family and domain databases

InterProiIPR027775. C2H2_Znf_fam.
IPR008916. Retrov_capsid_C.
IPR003309. Tscrpt_reg_SCAN.
[Graphical view]
PANTHERiPTHR10032. PTHR10032. 1 hit.
PfamiPF02023. SCAN. 1 hit.
[Graphical view]
SMARTiSM00431. SCAN. 1 hit.
[Graphical view]
SUPFAMiSSF47353. SSF47353. 1 hit.
PROSITEiPS50804. SCAN_BOX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P57086-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAATEPILAA TGSPAAVPPE KLEGAGSSSA PERNCVGSSL PEASPPAPEP
60 70 80 90 100
SSPNAAVPEA IPTPRAAASA ALELPLGPAP VSVAPQAEAE ARSTPGPAGS
110 120 130 140 150
RLGPETFRQR FRQFRYQDAA GPREAFRQLR ELSRQWLRPD IRTKEQIVEM
160 170
LVQEQLLAIL PEAARARRIR RRTDVRITG
Length:179
Mass (Da):19,082
Last modified:December 1, 2000 - v1
Checksum:i88AFEFC8E4DC9796
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF204271 mRNA. Translation: AAF59839.1.
CR457188 mRNA. Translation: CAG33469.1.
AL109965 Genomic DNA. Translation: CAC09390.1.
CH471077 Genomic DNA. Translation: EAW76150.1.
BC000785 mRNA. Translation: AAH00785.1.
BC036709 mRNA. Translation: AAH36709.1.
BC041022 mRNA. Translation: AAH41022.1.
CCDSiCCDS13269.1.
RefSeqiNP_057642.1. NM_016558.3.
UniGeneiHs.584909.

Genome annotation databases

EnsembliENST00000305978; ENSP00000301995; ENSG00000171222.
ENST00000373991; ENSP00000363103; ENSG00000171222.
ENST00000615116; ENSP00000481289; ENSG00000171222.
GeneIDi51282.
KEGGihsa:51282.
UCSCiuc002xeo.3. human.

Polymorphism databases

DMDMi10720272.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF204271 mRNA. Translation: AAF59839.1 .
CR457188 mRNA. Translation: CAG33469.1 .
AL109965 Genomic DNA. Translation: CAC09390.1 .
CH471077 Genomic DNA. Translation: EAW76150.1 .
BC000785 mRNA. Translation: AAH00785.1 .
BC036709 mRNA. Translation: AAH36709.1 .
BC041022 mRNA. Translation: AAH41022.1 .
CCDSi CCDS13269.1.
RefSeqi NP_057642.1. NM_016558.3.
UniGenei Hs.584909.

3D structure databases

ProteinModelPortali P57086.
SMRi P57086. Positions 104-162.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 119434. 15 interactions.
IntActi P57086. 8 interactions.
MINTi MINT-1435996.
STRINGi 9606.ENSP00000301995.

PTM databases

PhosphoSitei P57086.

Polymorphism databases

DMDMi 10720272.

Proteomic databases

MaxQBi P57086.
PaxDbi P57086.
PRIDEi P57086.

Protocols and materials databases

DNASUi 51282.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000305978 ; ENSP00000301995 ; ENSG00000171222 .
ENST00000373991 ; ENSP00000363103 ; ENSG00000171222 .
ENST00000615116 ; ENSP00000481289 ; ENSG00000171222 .
GeneIDi 51282.
KEGGi hsa:51282.
UCSCi uc002xeo.3. human.

Organism-specific databases

CTDi 51282.
GeneCardsi GC20M034542.
HGNCi HGNC:10566. SCAND1.
HPAi CAB034284.
MIMi 610416. gene.
neXtProti NX_P57086.
PharmGKBi PA34979.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG291024.
GeneTreei ENSGT00730000110971.
HOVERGENi HBG079091.
InParanoidi P57086.
OMAi PERNSAG.
OrthoDBi EOG7PS1JD.
PhylomeDBi P57086.

Miscellaneous databases

ChiTaRSi SCAND1. human.
GeneWikii SCAND1.
GenomeRNAii 51282.
NextBioi 54517.
PROi P57086.
SOURCEi Search...

Gene expression databases

Bgeei P57086.
CleanExi HS_SCAND1.
ExpressionAtlasi P57086. baseline and differential.
Genevestigatori P57086.

Family and domain databases

InterProi IPR027775. C2H2_Znf_fam.
IPR008916. Retrov_capsid_C.
IPR003309. Tscrpt_reg_SCAN.
[Graphical view ]
PANTHERi PTHR10032. PTHR10032. 1 hit.
Pfami PF02023. SCAN. 1 hit.
[Graphical view ]
SMARTi SM00431. SCAN. 1 hit.
[Graphical view ]
SUPFAMi SSF47353. SSF47353. 1 hit.
PROSITEi PS50804. SCAN_BOX. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Skin.

Entry informationi

Entry nameiSCND1_HUMAN
AccessioniPrimary (citable) accession number: P57086
Secondary accession number(s): Q6IAG7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: October 29, 2014
This is version 117 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3