##gff-version 3
P57078	UniProtKB	Chain	1	832	.	.	.	ID=PRO_0000086613;Note=Receptor-interacting serine/threonine-protein kinase 4	
P57078	UniProtKB	Domain	22	286	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P57078	UniProtKB	Repeat	485	514	.	.	.	Note=ANK 1	
P57078	UniProtKB	Repeat	518	547	.	.	.	Note=ANK 2	
P57078	UniProtKB	Repeat	551	580	.	.	.	Note=ANK 3	
P57078	UniProtKB	Repeat	584	613	.	.	.	Note=ANK 4	
P57078	UniProtKB	Repeat	617	647	.	.	.	Note=ANK 5	
P57078	UniProtKB	Repeat	651	680	.	.	.	Note=ANK 6	
P57078	UniProtKB	Repeat	684	713	.	.	.	Note=ANK 7	
P57078	UniProtKB	Repeat	717	746	.	.	.	Note=ANK 8	
P57078	UniProtKB	Repeat	750	780	.	.	.	Note=ANK 9	
P57078	UniProtKB	Repeat	782	811	.	.	.	Note=ANK 10	
P57078	UniProtKB	Region	325	368	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P57078	UniProtKB	Region	389	424	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P57078	UniProtKB	Compositional bias	330	355	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P57078	UniProtKB	Active site	143	143	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10027	
P57078	UniProtKB	Binding site	28	36	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P57078	UniProtKB	Binding site	51	51	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P57078	UniProtKB	Site	388	389	.	.	.	Note=Cleavage;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12446564;Dbxref=PMID:12446564	
P57078	UniProtKB	Site	426	427	.	.	.	Note=Cleavage;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12446564;Dbxref=PMID:12446564	
P57078	UniProtKB	Cross-link	51	51	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin);Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21931591;Dbxref=PMID:21931591	
P57078	UniProtKB	Cross-link	145	145	.	.	.	Note=Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin);Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:21931591;Dbxref=PMID:21931591	
P57078	UniProtKB	Alternative sequence	278	325	.	.	.	ID=VSP_004862;Note=In isoform 2. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|Ref.1	
P57078	UniProtKB	Natural variant	12	12	.	.	.	ID=VAR_030160;Note=A->G;Dbxref=dbSNP:rs6586239	
P57078	UniProtKB	Natural variant	81	81	.	.	.	ID=VAR_067331;Note=In BPS. I->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:22197488;Dbxref=dbSNP:rs387906922,PMID:22197488	
P57078	UniProtKB	Natural variant	121	121	.	.	.	ID=VAR_067332;Note=In BPS%3B loss of function. I->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:22197489;Dbxref=dbSNP:rs387906923,PMID:22197489	
P57078	UniProtKB	Natural variant	163	163	.	.	.	ID=VAR_081473;Note=In CHANDS%3B uncertain significance. G->D;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:23610050;Dbxref=dbSNP:rs764278537,PMID:23610050	
P57078	UniProtKB	Natural variant	177	177	.	.	.	ID=VAR_030161;Note=S->N;Dbxref=dbSNP:rs12482626	
P57078	UniProtKB	Natural variant	184	184	.	.	.	ID=VAR_067333;Note=In BPS%3B loss of function. T->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:22197489;Dbxref=PMID:22197489	
P57078	UniProtKB	Natural variant	189	189	.	.	.	ID=VAR_085697;Note=In BPS%3B uncertain significance. P->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25691407;Dbxref=PMID:25691407	
P57078	UniProtKB	Natural variant	284	284	.	.	.	ID=VAR_081474;Note=In CHANDS%3B uncertain significance. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26129644;Dbxref=PMID:26129644	
P57078	UniProtKB	Natural variant	462	462	.	.	.	ID=VAR_041050;Note=I->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55809511,PMID:17344846	
P57078	UniProtKB	Natural variant	463	463	.	.	.	ID=VAR_041051;Note=V->M;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55645753,PMID:17344846	
P57078	UniProtKB	Natural variant	496	496	.	.	.	ID=VAR_085698;Note=In BPS%3B uncertain significance. A->P;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25691407;Dbxref=PMID:25691407	
P57078	UniProtKB	Natural variant	562	562	.	.	.	ID=VAR_041052;Note=N->Y;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs55829311,PMID:17344846	
P57078	UniProtKB	Natural variant	666	666	.	.	.	ID=VAR_085699;Note=In BPS%3B uncertain significance. R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25691407;Dbxref=dbSNP:rs763794698,PMID:25691407	
P57078	UniProtKB	Natural variant	669	669	.	.	.	ID=VAR_041053;Note=R->H;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs56056485,PMID:17344846	
P57078	UniProtKB	Natural variant	749	749	.	.	.	ID=VAR_041054;Note=P->S;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs35537517,PMID:17344846	
P57078	UniProtKB	Sequence conflict	714	714	.	.	.	Note=M->V;Ontology_term=ECO:0000305;evidence=ECO:0000305