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P57054

- PIGP_HUMAN

UniProt

P57054 - PIGP_HUMAN

Protein

Phosphatidylinositol N-acetylglucosaminyltransferase subunit P

Gene

PIGP

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 114 (01 Oct 2014)
      Sequence version 3 (28 Nov 2012)
      Previous versions | rss
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    Functioni

    Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

    Catalytic activityi

    UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.

    Pathwayi

    GO - Molecular functioni

    1. phosphatidylinositol N-acetylglucosaminyltransferase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular protein metabolic process Source: Reactome
    2. C-terminal protein lipidation Source: Reactome
    3. post-translational protein modification Source: Reactome
    4. preassembly of GPI anchor in ER membrane Source: Reactome

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    GPI-anchor biosynthesis

    Enzyme and pathway databases

    BRENDAi2.4.1.198. 2681.
    ReactomeiREACT_952. Synthesis of glycosylphosphatidylinositol (GPI).
    UniPathwayiUPA00196.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphatidylinositol N-acetylglucosaminyltransferase subunit P (EC:2.4.1.198)
    Alternative name(s):
    Down syndrome critical region protein 5
    Down syndrome critical region protein C
    Phosphatidylinositol-glycan biosynthesis class P protein
    Short name:
    PIG-P
    Gene namesi
    Name:PIGP
    Synonyms:DCRC, DSCR5, DSCRC
    ORF Names:NPD010
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 21

    Organism-specific databases

    HGNCiHGNC:3046. PIGP.

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum membrane Source: Reactome
    2. glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex Source: MGI
    3. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA27498.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 158158Phosphatidylinositol N-acetylglucosaminyltransferase subunit PPRO_0000191783Add
    BLAST

    Proteomic databases

    PaxDbiP57054.
    PRIDEiP57054.

    PTM databases

    PhosphoSiteiP57054.

    Expressioni

    Tissue specificityi

    Ubiquitous.

    Gene expression databases

    ArrayExpressiP57054.
    BgeeiP57054.
    CleanExiHS_PIGP.
    GenevestigatoriP57054.

    Organism-specific databases

    HPAiHPA026921.

    Interactioni

    Subunit structurei

    Associates with PIGA, PIGC, PIGH, PIGQ and DPM2. The latter is not essential for activity.

    Protein-protein interaction databases

    BioGridi119391. 4 interactions.
    STRINGi9606.ENSP00000420037.

    Structurei

    3D structure databases

    ProteinModelPortaliP57054.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei40 – 6021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei80 – 10021HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PIGP family.Curated

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG133279.
    HOVERGENiHBG000430.
    InParanoidiP57054.
    KOiK03861.
    OMAiSEVNRMF.
    OrthoDBiEOG776SRZ.
    PhylomeDBiP57054.
    TreeFamiTF323799.

    Family and domain databases

    InterProiIPR013717. PIG-P.
    IPR016542. PIG-P_GPI19.
    [Graphical view]
    PfamiPF08510. PIG-P. 1 hit.
    [Graphical view]
    PIRSFiPIRSF008765. PIG-P_GPI19. 1 hit.

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform B (identifier: P57054-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MVPRSTSLAL IVFLFHRLSK APGKMVENSP SPLPERAIYG FVLFLSSQFG    50
    FILYLVWAFI PESWLNSLGL TYWPQKYWAV ALPVYLLIAI VIGYVLLFGI 100
    NMMSTSPLDS IHTITDNYAK NQQQKKYQEE AIPALRDISI SEVNQMFFLA 150
    AKELYTKN 158
    Length:158
    Mass (Da):18,059
    Last modified:November 28, 2012 - v3
    Checksum:i924CCEB84C9D2721
    GO
    Isoform A (identifier: P57054-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-24: Missing.

    Show »
    Length:134
    Mass (Da):15,408
    Checksum:i47A2122FA663EB64
    GO
    Isoform C (identifier: P57054-3) [UniParc]FASTAAdd to Basket

    Also known as: DCRC-S

    The sequence of this isoform differs from the canonical sequence as follows:
         1-50: Missing.
         51-52: FI → MV

    Show »
    Length:108
    Mass (Da):12,510
    Checksum:iCF1E65158429EE48
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti3 – 31P → S in BAA96872. (PubMed:10814524)Curated
    Sequence conflicti90 – 901I → V in BAA96873. (PubMed:10814524)Curated
    Sequence conflicti90 – 901I → V in AAF32289. (PubMed:10907851)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti9 – 91A → T.5 Publications
    Corresponds to variant rs2507733 [ dbSNP | Ensembl ].
    VAR_061521
    Natural varianti118 – 1181Y → C.
    Corresponds to variant rs16994704 [ dbSNP | Ensembl ].
    VAR_050538
    Natural varianti136 – 1361R → S.
    Corresponds to variant rs2276231 [ dbSNP | Ensembl ].
    VAR_050539

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 5050Missing in isoform C. 3 PublicationsVSP_004203Add
    BLAST
    Alternative sequencei1 – 2424Missing in isoform A. 5 PublicationsVSP_004202Add
    BLAST
    Alternative sequencei51 – 522FI → MV in isoform C. 3 PublicationsVSP_004204

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB037162 mRNA. Translation: BAA96871.1.
    AB037163 mRNA. Translation: BAA96872.1.
    AB037164 mRNA. Translation: BAA96873.1.
    AB035742 mRNA. Translation: BAA95633.1.
    AB035743 mRNA. Translation: BAA95634.1.
    AB035744 mRNA. Translation: BAA95635.1.
    AB035745 mRNA. Translation: BAA95636.1.
    AF216305 mRNA. Translation: AAF32289.1.
    AB039659 mRNA. Translation: BAB12395.1.
    AF237812 mRNA. Translation: AAG09757.1.
    BT007053 mRNA. Translation: AAP35702.1.
    AK314457 mRNA. Translation: BAG37065.1.
    AK316609 mRNA. Translation: BAG38196.1.
    AB451328 mRNA. Translation: BAG70142.1.
    AB451472 mRNA. Translation: BAG70286.1.
    AP000704 Genomic DNA. No translation available.
    AP001429 Genomic DNA. No translation available.
    AP001431 Genomic DNA. No translation available.
    AP001727 Genomic DNA. Translation: BAA95512.1.
    CH471079 Genomic DNA. Translation: EAX09724.1.
    CH471079 Genomic DNA. Translation: EAX09725.1.
    CH471079 Genomic DNA. Translation: EAX09727.1.
    CH471079 Genomic DNA. Translation: EAX09726.1.
    CH471079 Genomic DNA. Translation: EAX09728.1.
    BC005180 mRNA. Translation: AAH05180.1.
    BC011007 mRNA. Translation: AAH11007.1.
    CCDSiCCDS13649.1. [P57054-1]
    CCDS13650.1. [P57054-2]
    PIRiJC7301.
    JC7302.
    RefSeqiNP_710148.1. NM_153681.2.
    NP_710149.1. NM_153682.2. [P57054-2]
    XP_005261047.1. XM_005260990.2. [P57054-2]
    XP_006724073.1. XM_006724010.1. [P57054-2]
    UniGeneiHs.656565.
    Hs.716087.

    Genome annotation databases

    EnsembliENST00000360525; ENSP00000353719; ENSG00000185808. [P57054-2]
    ENST00000399098; ENSP00000382049; ENSG00000185808. [P57054-3]
    ENST00000399102; ENSP00000382053; ENSG00000185808. [P57054-2]
    ENST00000399103; ENSP00000382054; ENSG00000185808. [P57054-2]
    ENST00000464265; ENSP00000420037; ENSG00000185808. [P57054-1]
    GeneIDi51227.
    KEGGihsa:51227.
    UCSCiuc002yvw.1. human. [P57054-1]
    uc002yvy.2. human. [P57054-3]

    Polymorphism databases

    DMDMi425906062.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB037162 mRNA. Translation: BAA96871.1 .
    AB037163 mRNA. Translation: BAA96872.1 .
    AB037164 mRNA. Translation: BAA96873.1 .
    AB035742 mRNA. Translation: BAA95633.1 .
    AB035743 mRNA. Translation: BAA95634.1 .
    AB035744 mRNA. Translation: BAA95635.1 .
    AB035745 mRNA. Translation: BAA95636.1 .
    AF216305 mRNA. Translation: AAF32289.1 .
    AB039659 mRNA. Translation: BAB12395.1 .
    AF237812 mRNA. Translation: AAG09757.1 .
    BT007053 mRNA. Translation: AAP35702.1 .
    AK314457 mRNA. Translation: BAG37065.1 .
    AK316609 mRNA. Translation: BAG38196.1 .
    AB451328 mRNA. Translation: BAG70142.1 .
    AB451472 mRNA. Translation: BAG70286.1 .
    AP000704 Genomic DNA. No translation available.
    AP001429 Genomic DNA. No translation available.
    AP001431 Genomic DNA. No translation available.
    AP001727 Genomic DNA. Translation: BAA95512.1 .
    CH471079 Genomic DNA. Translation: EAX09724.1 .
    CH471079 Genomic DNA. Translation: EAX09725.1 .
    CH471079 Genomic DNA. Translation: EAX09727.1 .
    CH471079 Genomic DNA. Translation: EAX09726.1 .
    CH471079 Genomic DNA. Translation: EAX09728.1 .
    BC005180 mRNA. Translation: AAH05180.1 .
    BC011007 mRNA. Translation: AAH11007.1 .
    CCDSi CCDS13649.1. [P57054-1 ]
    CCDS13650.1. [P57054-2 ]
    PIRi JC7301.
    JC7302.
    RefSeqi NP_710148.1. NM_153681.2.
    NP_710149.1. NM_153682.2. [P57054-2 ]
    XP_005261047.1. XM_005260990.2. [P57054-2 ]
    XP_006724073.1. XM_006724010.1. [P57054-2 ]
    UniGenei Hs.656565.
    Hs.716087.

    3D structure databases

    ProteinModelPortali P57054.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 119391. 4 interactions.
    STRINGi 9606.ENSP00000420037.

    PTM databases

    PhosphoSitei P57054.

    Polymorphism databases

    DMDMi 425906062.

    Proteomic databases

    PaxDbi P57054.
    PRIDEi P57054.

    Protocols and materials databases

    DNASUi 51227.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000360525 ; ENSP00000353719 ; ENSG00000185808 . [P57054-2 ]
    ENST00000399098 ; ENSP00000382049 ; ENSG00000185808 . [P57054-3 ]
    ENST00000399102 ; ENSP00000382053 ; ENSG00000185808 . [P57054-2 ]
    ENST00000399103 ; ENSP00000382054 ; ENSG00000185808 . [P57054-2 ]
    ENST00000464265 ; ENSP00000420037 ; ENSG00000185808 . [P57054-1 ]
    GeneIDi 51227.
    KEGGi hsa:51227.
    UCSCi uc002yvw.1. human. [P57054-1 ]
    uc002yvy.2. human. [P57054-3 ]

    Organism-specific databases

    CTDi 51227.
    GeneCardsi GC21M038435.
    HGNCi HGNC:3046. PIGP.
    HPAi HPA026921.
    MIMi 605938. gene.
    neXtProti NX_P57054.
    PharmGKBi PA27498.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG133279.
    HOVERGENi HBG000430.
    InParanoidi P57054.
    KOi K03861.
    OMAi SEVNRMF.
    OrthoDBi EOG776SRZ.
    PhylomeDBi P57054.
    TreeFami TF323799.

    Enzyme and pathway databases

    UniPathwayi UPA00196 .
    BRENDAi 2.4.1.198. 2681.
    Reactomei REACT_952. Synthesis of glycosylphosphatidylinositol (GPI).

    Miscellaneous databases

    GeneWikii PIGP.
    GenomeRNAii 51227.
    NextBioi 35535499.
    PROi P57054.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi P57054.
    Bgeei P57054.
    CleanExi HS_PIGP.
    Genevestigatori P57054.

    Family and domain databases

    InterProi IPR013717. PIG-P.
    IPR016542. PIG-P_GPI19.
    [Graphical view ]
    Pfami PF08510. PIG-P. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF008765. PIG-P_GPI19. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2."
      Shibuya K., Kudoh J., Minoshima S., Kawasaki K., Asakawa S., Shimizu N.
      Biochem. Biophys. Res. Commun. 271:693-698(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A; B AND C), VARIANT THR-9.
      Tissue: Testis.
    2. "A novel gene, DSCR5, from the distal Down syndrome critical region on chromosome 21q22.2."
      Togashi T., Choi D.-K., Taylor T.D., Suzuki Y., Sugano S., Hattori M., Sakaki Y.
      DNA Res. 7:207-212(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A; B AND C), VARIANT THR-9.
    3. "Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2."
      Watanabe R., Murakami Y., Marmor M.D., Inoue N., Maeda Y., Hino J., Kangawa K., Julius M., Kinoshita T.
      EMBO J. 19:4402-4411(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], PROTEIN SEQUENCE OF 26-33, FUNCTION (ISOFORM A).
    4. Song H., Gao G., Peng Y., Ren S., Chen Z., Han Z.
      Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM B), VARIANT THR-9.
      Tissue: Pituitary.
    5. "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N., Chen X., Rolfs A., Halleck A., Hines L., Eisenstein S., Koundinya M., Raphael J., Moreira D., Kelley T., LaBaer J., Lin Y., Phelan M., Farmer A.
      Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A).
    6. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A AND B), VARIANT THR-9.
      Tissue: Kidney and Umbilical cord blood.
    7. "Human protein factory for converting the transcriptome into an in vitro-expressed proteome."
      Goshima N., Kawamura Y., Fukumoto A., Miura A., Honma R., Satoh R., Wakamatsu A., Yamamoto J., Kimura K., Nishikawa T., Andoh T., Iida Y., Ishikawa K., Ito E., Kagawa N., Kaminaga C., Kanehori K., Kawakami B.
      , Kenmochi K., Kimura R., Kobayashi M., Kuroita T., Kuwayama H., Maruyama Y., Matsuo K., Minami K., Mitsubori M., Mori M., Morishita R., Murase A., Nishikawa A., Nishikawa S., Okamoto T., Sakagami N., Sakamoto Y., Sasaki Y., Seki T., Sono S., Sugiyama A., Sumiya T., Takayama T., Takayama Y., Takeda H., Togashi T., Yahata K., Yamada H., Yanagisawa Y., Endo Y., Imamoto F., Kisu Y., Tanaka S., Isogai T., Imai J., Watanabe S., Nomura N.
      Nat. Methods 5:1011-1017(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM C).
    8. "The DNA sequence of human chromosome 21."
      Hattori M., Fujiyama A., Taylor T.D., Watanabe H., Yada T., Park H.-S., Toyoda A., Ishii K., Totoki Y., Choi D.-K., Groner Y., Soeda E., Ohki M., Takagi T., Sakaki Y., Taudien S., Blechschmidt K., Polley A.
      , Menzel U., Delabar J., Kumpf K., Lehmann R., Patterson D., Reichwald K., Rump A., Schillhabel M., Schudy A., Zimmermann W., Rosenthal A., Kudoh J., Shibuya K., Kawasaki K., Asakawa S., Shintani A., Sasaki T., Nagamine K., Mitsuyama S., Antonarakis S.E., Minoshima S., Shimizu N., Nordsiek G., Hornischer K., Brandt P., Scharfe M., Schoen O., Desario A., Reichelt J., Kauer G., Bloecker H., Ramser J., Beck A., Klages S., Hennig S., Riesselmann L., Dagand E., Wehrmeyer S., Borzym K., Gardiner K., Nizetic D., Francis F., Lehrach H., Reinhardt R., Yaspo M.-L.
      Nature 405:311-319(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    9. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], VARIANT THR-9.
    10. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM A).
      Tissue: Brain.

    Entry informationi

    Entry nameiPIGP_HUMAN
    AccessioniPrimary (citable) accession number: P57054
    Secondary accession number(s): B2RB18
    , B2RE99, B5BU92, D3DSG7, J3KR75, Q53Y28, Q96KI1, Q9NZA6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: November 28, 2012
    Last modified: October 1, 2014
    This is version 114 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. Human chromosome 21
      Human chromosome 21: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3