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P57005 (SODC_NEIMA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 97. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Superoxide dismutase [Cu-Zn]
EC=1.15.1.1
Gene names
Name:sodC
Ordered Locus Names:NMA1617
OrganismNeisseria meningitidis serogroup A / serotype 4A (strain Z2491) [Complete proteome] [HAMAP]
Taxonomic identifier122587 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria ›

Protein attributes

Sequence length186 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 1 copper ion per subunit By similarity.

Binds 1 zinc ion per subunit By similarity.

Subunit structure

Homodimer By similarity.

Subcellular location

Periplasm By similarity.

Sequence similarities

Belongs to the Cu-Zn superoxide dismutase family.

Ontologies

Keywords
   Cellular componentPeriplasm
   DomainSignal
   LigandCopper
Metal-binding
Zinc
   Molecular functionAntioxidant
Oxidoreductase
   PTMDisulfide bond
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Biological_processsuperoxide metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentperiplasmic space

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 186164Superoxide dismutase [Cu-Zn]
PRO_0000032833

Sites

Metal binding791Copper; catalytic By similarity
Metal binding811Copper; catalytic By similarity
Metal binding1041Copper; catalytic By similarity
Metal binding1041Zinc; structural By similarity
Metal binding1131Zinc; structural By similarity
Metal binding1221Zinc; structural By similarity
Metal binding1251Zinc; structural By similarity
Metal binding1601Copper; catalytic By similarity

Amino acid modifications

Disulfide bond86 ↔ 182 By similarity

Secondary structure

1 ................................ 186
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P57005 [UniParc].

Last modified December 1, 2000. Version 1.
Checksum: 04C84AB87FC7522D

FASTA18619,550
        10         20         30         40         50         60 
MNMKTLLALA VSAVCSVSVA QAHEHNTIPK GASIEVKVQQ LDPVNGNKDV GTVTITESNY 

        70         80         90        100        110        120 
GLVFTPDLQG LSEGLHGFHI HENPSCEPKE KEGKLTAGLG AGGHWDPKGA KQHGYPWQDD 

       130        140        150        160        170        180 
AHLGDLPALT VLHDGTATNP VLAPRLKHLD DVRGHSIMIH TGGDNHSDHP APLGGGGPRM 


ACGVIK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL157959 Genomic DNA. Translation: CAM08755.1.
PIRE81855.
RefSeqYP_002342924.1. NC_003116.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2AQNX-ray1.40A/B/C23-186[»]
2AQPX-ray1.30A/B23-186[»]
2AQQX-ray1.65A/B/C23-186[»]
2AQTX-ray1.80A/B/C23-186[»]
ProteinModelPortalP57005.
SMRP57005. Positions 32-186.
ModBaseSearch...

Protein-protein interaction databases

STRING122587.NMA1617.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAM08755; CAM08755; NMA1617.
GeneID908006.
KEGGnma:NMA1617.
PATRIC20364347. VBINeiMen132687_1877.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG2032.
HOGENOMHOG000263449.
KOK04565.
OMANTNSHQG.
ProtClustDBCLSK870677.

Enzyme and pathway databases

BioCycNMEN122587:GI3Q-1427-MONOMER.

Family and domain databases

Gene3D2.60.40.200. 1 hit.
InterProIPR024134. SOD_Cu/Zn_/chaperones.
IPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PANTHERPTHR10003. PTHR10003. 1 hit.
PfamPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMSSF49329. SOD_Cu_Zn. 1 hit.
PROSITEPS00087. SOD_CU_ZN_1. 1 hit.
PS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP57005.

Entry information

Entry nameSODC_NEIMA
AccessionPrimary (citable) accession number: P57005
Secondary accession number(s): A1ISJ6
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: December 1, 2000
Last modified: May 1, 2013
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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