Reviewed,
UniProtKB/Swiss-Prot P56954 (MQO_CAMJE)
Last modified
June 16, 2009.
Version 48.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Probable malate:quinone oxidoreductase EC=1.1.99.16 Alternative name(s): Malate dehydrogenase [acceptor] MQO | ||||
| Gene names |
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| Organism | Campylobacter jejuni [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 197 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Campylobacteraceae › Campylobacter |
Protein attributes
| Sequence length | 448 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Catalyzes oxidation of malate to oxaloacetate in the citric acid cycle. Donates electrons to quinones of the electron transfer chain By similarity. |
| Catalytic activity | (S)-malate + acceptor = oxaloacetate + reduced acceptor. HAMAP MF_00212 |
| Cofactor | FAD. The FAD is tightly bound By similarity. |
| Pathway | Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00212 |
| Sequence similarities | Belongs to the MQO family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Tricarboxylic acid cycle |
| Ligand | FAD Flavoprotein |
| Molecular function | Oxidoreductase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycleInferred from electronic annotation. Source: HAMAP |
| Molecular function | malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 448 | 448 | Probable malate:quinone oxidoreductase HAMAP MF_00212 | PRO_0000128708 | |||
Sequences
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References
| [1] | "The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences." Parkhill J., Wren B.W., Mungall K.L., Ketley J.M., Churcher C.M., Basham D., Chillingworth T., Davies R.M., Feltwell T., Holroyd S., Jagels K., Karlyshev A.V., Moule S., Pallen M.J., Penn C.W., Quail M.A., Rajandream M.A., Rutherford K.M. Barrell B.G.Nature 403:665-668(2000) [PubMed: 10688204] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: NCTC 11168 / Serotype O:2. |
Cross-references
Sequence databases | |
|---|---|
| AL111168 Genomic DNA. Translation: CAL34543.1. | |
| PIR | G81382. |
| RefSeq | YP_002343830.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 904716. |
| GenomeReviews | Gene locus Cj0393c in contig AL111168_GR. |
| KEGG | cje:Cj0393c. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| HOGENOM | P56954. |
| OMA | P56954. FELERFY. |
Enzyme and pathway databases | |
| BioCyc | CJEJ192222:CJ0393C-MON. |
| BRENDA | 1.1.99.16. 255835. |
Family and domain databases | |
| HAMAP | MF_00212. [Tree] |
| InterPro | IPR006076. FAD-dep_OxRdtase. [Graphical view] |
| Pfam | PF01266. DAO. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | MQO_CAMJE | ||||||||
| Accession | Primary (citable) accession number: P56954 Secondary accession number(s): Q0PBB7 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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