ID   REPA1_BUCAI             Reviewed;         283 AA.
AC   P56936; Q9R6R5;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   RecName: Full=Probable replication-associated protein repA1;
GN   Name=repA1; OrderedLocusNames=BUpL01;
OS   Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon
OS   pisum symbiotic bacterium).
OG   Plasmid pLeu (pBAp1).
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC   Erwiniaceae; Buchnera.
OX   NCBI_TaxID=107806;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10688696; DOI=10.1007/s002849910052;
RA   Soler T., Latorre A., Sabater B., Silva F.J.;
RT   "Molecular characterization of the Leucine plasmid from Buchnera
RT   aphidicola, primary endosymbiont of the aphid Acyrthosiphon pisum.";
RL   Curr. Microbiol. 40:264-268(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=APS;
RX   PubMed=10993077; DOI=10.1038/35024074;
RA   Shigenobu S., Watanabe H., Hattori M., Sakaki Y., Ishikawa H.;
RT   "Genome sequence of the endocellular bacterial symbiont of aphids Buchnera
RT   sp. APS.";
RL   Nature 407:81-86(2000).
CC   -!- FUNCTION: This protein is essential for plasmid replication; it is
CC       involved in copy control functions. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the IncFII RepA family. {ECO:0000305}.
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DR   EMBL; AJ006878; CAB56190.1; -; Genomic_DNA.
DR   EMBL; AP001071; BAA95420.1; -; Genomic_DNA.
DR   RefSeq; NP_057965.1; NC_002253.1.
DR   RefSeq; WP_010892291.1; NC_002253.1.
DR   AlphaFoldDB; P56936; -.
DR   EnsemblBacteria; BAA95420; BAA95420; BAA95420.
DR   KEGG; buc:BUpL01; -.
DR   PATRIC; fig|107806.10.peg.7; -.
DR   HOGENOM; CLU_084990_0_0_6; -.
DR   Proteomes; UP000001806; Plasmid pLeu.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
DR   InterPro; IPR003446; Plasmid_replication_init_RepA.
DR   NCBIfam; NF040977; RepA_IncFII_LM; 1.
DR   Pfam; PF02387; IncFII_repA; 1.
PE   3: Inferred from homology;
KW   DNA replication; Plasmid; Plasmid copy control; Reference proteome.
FT   CHAIN           1..283
FT                   /note="Probable replication-associated protein repA1"
FT                   /id="PRO_0000216227"
SQ   SEQUENCE   283 AA;  32933 MW;  5A27ED464A6E04BD CRC64;
     MIIRKCYINN PNPFFTPPKN NKRRPSFICY AMKRASEIDV ARCELNYILQ IKNIKIGFPV
     KRFRRLNEHR ACAMRAMVLA MLYHFNISSD LVQASVEQLS DECGLSTLSK AGNKSITRAS
     RLITNFMEPM GFVTCKKTWD KILGNYMPKM ITLTPLFFML FGVSEKKLMD AKKQQLGWIN
     KNLISKGFKP ITMIDAKRRS KDTQIKNIFQ YRISKHAFYK KKRNAQRLIS LDEKEARQTI
     LRALVAKYSI TELTKLGPNG LKKQVNISYY YLRKIATNTY PDN
//