UniProtKB - P56927 (SYQ_NEIMB)
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Protein
Glutamine--tRNA ligase
Gene
glnS
Organism
Neisseria meningitidis serogroup B (strain MC58)
Status
Functioni
Catalytic activityi
ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 68 | L-glutamineUniRule annotation | 1 | |
Binding sitei | 213 | L-glutamineUniRule annotation | 1 | |
Binding sitei | 232 | ATPUniRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 36 – 38 | ATPUniRule annotation | 3 | |
Nucleotide bindingi | 42 – 48 | ATPUniRule annotation | 7 | |
Nucleotide bindingi | 264 – 265 | ATPUniRule annotation | 2 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- glutamine-tRNA ligase activity Source: UniProtKB-EC
GO - Biological processi
- glutaminyl-tRNA aminoacylation Source: InterPro
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)Alternative name(s): Glutaminyl-tRNA synthetaseUniRule annotation Short name: GlnRSUniRule annotation |
Gene namesi | Name:glnSUniRule annotation Ordered Locus Names:NMB1560 |
Organismi | Neisseria meningitidis serogroup B (strain MC58) |
Taxonomic identifieri | 122586 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Neisseriales › Neisseriaceae › Neisseria › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000195839 | 1 – 562 | Glutamine--tRNA ligaseAdd BLAST | 562 |
Proteomic databases
PaxDbi | P56927. |
Interactioni
Subunit structurei
Monomer.UniRule annotation
Protein-protein interaction databases
STRINGi | 122586.NMB1560. |
Structurei
3D structure databases
ProteinModelPortali | P56927. |
SMRi | P56927. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 35 – 45 | "HIGH" regionUniRule annotationAdd BLAST | 11 | |
Motifi | 271 – 275 | "KMSKS" regionUniRule annotation | 5 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG4105CX6. Bacteria. COG0008. LUCA. |
HOGENOMi | HOG000259232. |
KOi | K01886. |
OMAi | VTHSICT. |
OrthoDBi | POG091H00G9. |
Family and domain databases
Gene3Di | 1.10.1160.10. 1 hit. 2.40.240.10. 3 hits. 3.40.50.620. 2 hits. |
HAMAPi | MF_00126. Gln_tRNA_synth. 1 hit. |
InterProi | View protein in InterPro IPR004514. Gln-tRNA-synth. IPR022861. Gln_tRNA_ligase_bac. IPR000924. Glu/Gln-tRNA-synth. IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom. IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd. IPR020061. Glu_tRNA_lig_a-bdl. IPR020056. Rbsml_L25/Gln-tRNA_synth_N. IPR011035. Ribosomal_L25/Gln-tRNA_synth. IPR014729. Rossmann-like_a/b/a_fold. |
Pfami | View protein in Pfam PF00749. tRNA-synt_1c. 1 hit. PF03950. tRNA-synt_1c_C. 1 hit. |
PRINTSi | PR00987. TRNASYNTHGLU. |
SUPFAMi | SSF50715. SSF50715. 1 hit. |
TIGRFAMsi | TIGR00440. glnS. 1 hit. |
PROSITEi | View protein in PROSITE PS00178. AA_TRNA_LIGASE_I. 1 hit. |
i Sequence
Sequence statusi: Complete.
P56927-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLNKDQFADN HFIRTIIEED LESGKHTAVQ TRFPPEPNGY LHIGHAKSIC
60 70 80 90 100
LNFGLAYIYD GLCNLRFDDT NPEKENDEYV NAIKEDVEWL GFHWAGEPRF
110 120 130 140 150
ASNYFDQLYD YAVGLIKDGK AYVDDLTPEE MREYRGTLTE AGKNSPYRDR
160 170 180 190 200
SVEENLDLFT RMKNGEFPDG SKTLRLKIDM ASGNINMRDP VIYRIRRAHH
210 220 230 240 250
HNTGDKWCIY PMYDYTHCIS DAIEGITHSL CTLEFEAHRP LYDCVLDNIP
260 270 280 290 300
APHATRPRQY EFSRLELLYT ITSKRKLNQL VVEKHVSGWD DPRMPTISGM
310 320 330 340 350
RRRGYTPEGL RLFAKRAGIS KSENIVDMSV LEGAIREELE NSAPRLMAVL
360 370 380 390 400
NPLKVTLTNF ETGRTQSRRA AFHPNHEEMG EREVPISQTI YIEADDFAEN
410 420 430 440 450
PPKGFKRLIP GGEVRLRHGY VIKCDEVVKD EAGNVVELKC SIDHDTLGKN
460 470 480 490 500
PEGRKVKGVI HWVSAEHAAE IKVRLYDRLF TVERPDAVRG EDGEYLPFTD
510 520 530 540 550
FLNPESVKEI TAYAEPAAKD LPAESRWQFE RIGYFVTDRK DHGKDTPVFN
560
RTVTLKDSWQ PK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE002098 Genomic DNA. Translation: AAF41914.1. |
PIRi | E81069. |
RefSeqi | NP_274567.2. NC_003112.2. |
Genome annotation databases
EnsemblBacteriai | AAF41914; AAF41914; NMB1560. |
GeneIDi | 904126. |
KEGGi | nme:NMB1560. |
PATRICi | fig|122586.8.peg.2007. |
Similar proteinsi
Entry informationi
Entry namei | SYQ_NEIMB | |
Accessioni | P56927Primary (citable) accession number: P56927 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | May 30, 2000 | |
Last modified: | February 28, 2018 | |
This is version 111 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |