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P56926 (SYQ_DEIRA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamine--tRNA ligase

EC=6.1.1.18
Alternative name(s):
Glutaminyl-tRNA synthetase
Short name=GlnRS
Gene names
Name:glnS
Ordered Locus Names:DR_2611
OrganismDeinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) [Reference proteome] [HAMAP]
Taxonomic identifier243230 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciDeinococcalesDeinococcaceaeDeinococcus

Protein attributes

Sequence length852 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln). HAMAP-Rule MF_00126

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00126

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00126.

Sequence similarities

In the N-terminal section; belongs to the class-I aminoacyl-tRNA synthetase family.

In the C-terminal section; belongs to the GatB/GatE family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 852852Glutamine--tRNA ligase HAMAP-Rule MF_00126
PRO_0000195832

Regions

Region1 – 635635Glutaminyl-tRNA synthetase HAMAP-Rule MF_00126
Region636 – 852217GatB-like HAMAP-Rule MF_00126
Motif74 – 8411"HIGH" region HAMAP-Rule MF_00126
Motif308 – 3125"KMSKS" region HAMAP-Rule MF_00126

Sites

Binding site3111ATP By similarity

Secondary structure

....................................................................................................... 852
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P56926 [UniParc].

Last modified May 30, 2000. Version 1.
Checksum: 82911AA229D25F79

FASTA85293,471
        10         20         30         40         50         60 
MGAFGWEQDR GAPFSGRSPR ILTRMTDAPR PTAGADAPAR PPAAPLVAPN FITEIIERDL 

        70         80         90        100        110        120 
EAGKYPRVVT RFPPDPSGYA HLGHVFASLL DFNTARQYGG QFNLRMDDTN PELARQEYVD 

       130        140        150        160        170        180 
SIADDLKWLG LDWGEHFYYA SDYFDRYYAY AEQLIRQGDA YVESVSPEEL SRLRGNATTP 

       190        200        210        220        230        240 
GTPSPYRDRS VEENLDLLRR MKAGEFADGE HVLRAKIDLT APNMKLRDPV LYRIVNKPHF 

       250        260        270        280        290        300 
RTSDEWHIYP AYDFEHPLQD AIEGVTHSMC SLEFVDNRAI YDWLMEKLNF DPRPHQYEFG 

       310        320        330        340        350        360 
RRGLEYTITS KRKLRELVQA GRVSGWDDPR MPTLRAQRRL GVTPEAVRAF AAQIGVSRTN 

       370        380        390        400        410        420 
RTVDIAVYEN AVRDDLNHRA PRVMAVLDPV KVTLTNLDGE KTLSLPYWPH DVVRDSPDGL 

       430        440        450        460        470        480 
VGMPGGGRVA PEEAVRDVPL TRELYIERDD FSPAPPKGFK RLTPGGTVRL RGAGIIRADD 

       490        500        510        520        530        540 
FGTDEAGQVT HIRATLLGED AKAAGVIHWV SAERALPAEF RLYDRLFRVP HPEGENADVE 

       550        560        570        580        590        600 
DDSAGPAEHE AEPGAGQETA PVSQGFMRYL TPDSLRVLRG YVEPSVAGDP ADTRYQFERQ 

       610        620        630        640        650        660 
GYFWRDPVEL ERVDSREDAL VFGRIITLKD TWGKQGGGTQ QKAEGKKRPS TKGRGPDEVR 

       670        680        690        700        710        720 
GEGSSSPAKA HAPKAQPLTP EQDAEFTRLL GLGASEGDAR TIARDPALLA FVGGAAPGDT 

       730        740        750        760        770        780 
FAQVASWTVN ELVAGLRAGE VKVRAADLAP LAEGVASGQL SARIAREALA RAAASGDAPL 

       790        800        810        820        830        840 
TIIEREGLNA GLSAEALQQV VAQVIAANPD KAEAYRGGKT ALLGFFTGQV MRATAGKADP 

       850 
QALAAALKDA LA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000513 Genomic DNA. Translation: AAF12148.1.
PIRA75253.
RefSeqNP_296330.1. NC_001263.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2HZ7X-ray2.30A2-852[»]
ProteinModelPortalP56926.
SMRP56926. Positions 43-632.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING243230.DR_2611.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAF12148; AAF12148; DR_2611.
GeneID1798434.
KEGGdra:DR_2611.
PATRIC21632975. VBIDeiRad64572_2858.

Phylogenomic databases

eggNOGCOG0064.
HOGENOMHOG000259232.
KOK01886.
OMAPLYEWVL.
OrthoDBEOG6DRPF7.
ProtClustDBPRK14703.

Enzyme and pathway databases

BioCycDRAD243230:GH46-2666-MONOMER.
MetaCyc:MONOMER-14055.

Family and domain databases

Gene3D1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPMF_00126. Gln_tRNA_synth.
InterProIPR018027. Asn/Gln_amidotransferase.
IPR003789. Asn/Gln_tRNA_amidoTrfrase-rel.
IPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PfamPF02637. GatB_Yqey. 1 hit.
PF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SMARTSM00845. GatB_Yqey. 1 hit.
[Graphical view]
SUPFAMSSF50715. SSF50715. 2 hits.
SSF89095. SSF89095. 1 hit.
TIGRFAMsTIGR00440. glnS. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceP56926.

Entry information

Entry nameSYQ_DEIRA
AccessionPrimary (citable) accession number: P56926
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: February 19, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries