P56887 (KPPR_SINMW) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoribulokinase
Short name=PRK
Short name=PRKase
EC=2.7.1.19

Alternative name(s):
Phosphopentokinase

Gene names

Name:	cbbP
Ordered Locus Names:	Smed_3921

Encoded on

Plasmid pSMED01

Organism

Sinorhizobium medicae (strain WSM419) (Ensifer medicae) [Complete proteome] [HAMAP]

Taxonomic identifier

366394 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › Sinorhizobium medicae

Protein attributes

Sequence length	289 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + D-ribulose 5-phosphate = ADP + D-ribulose 1,5-bisphosphate.
Pathway	Carbohydrate biosynthesis; Calvin cycle.
Sequence similarities	Belongs to the phosphoribulokinase family.

Ontologies

Keywords
Biological process	Calvin cycle
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome Plasmid
Gene Ontology (GO)
Biological_process	reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribulokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 289	289	Phosphoribulokinase		PRO_0000201956
Regions
	Nucleotide binding	12 – 20	9	ATP By similarity
Experimental info
	Sequence conflict	77	1	E → D in AAF25376. Ref.1
	Sequence conflict	80	1	E → Q in AAF25376. Ref.1
	Sequence conflict	279	1	H → N in AAF25376. Ref.1
	Sequence conflict	282	1	L → I in AAF25376. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	P56887 [UniParc]. Last modified November 13, 2007. Version 2. Checksum: A74ED5CCEAD465F9	FASTA	289	32,970
	10 20 30 40 50 60 MSAKYPIISI TGSSGAGTTT VKDTFEKIFK RENISASFIE GDAFHRYDRE TMRSKIAEEK 70 80 90 100 110 120 ARGVDFTHFS AEANELEILE SVFAEYGRRG VGRTRHYVHD DAEAVKFGSD PGTFTDWEEF 130 140 150 160 170 180 RDSDLLFYEG LHGCAVTDTI NLAQHCDLKI GVVPVINLEW IQKIHRDKAT RGYSTEAVTD 190 200 210 220 230 240 TILRRMPDYV HYICPQFSLT DINFQRVPIV DTSNPFIARW IPTPAESILV IRFAKPQSID 250 260 270 280 FPYLLSMLHN SYMSRANSIV VPGDKLDLAM QLIFTPLIHK LLERKHRMS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genetic regulation of C1 metabolism in Sinorhizobium meliloti." Fenner B.J., Tiwari R.P., Dilworth M.J. Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete sequence of Sinorhizobium medicae WSM419 plasmid pSMED01." US DOE Joint Genome Institute Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Reeve W.G., Richardson P. Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: WSM419.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF211846 Genomic DNA. Translation: AAF25376.1. CP000739 Genomic DNA. Translation: ABR62731.1.
RefSeq	YP_001312664.1. NC_009620.1.
3D structure databases
ProteinModelPortal	P56887.
SMR	P56887. Positions 2-282.
ModBase	Search...
Protein-protein interaction databases
STRING	366394.Smed_3921.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABR62731; ABR62731; Smed_3921.
GeneID	5318706.
KEGG	smd:Smed_3921.
PATRIC	23613388. VBISinMed134228_0367.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG3954.
HOGENOM	HOG000272991.
KO	K00855.
OMA	LGRHISY.
ProtClustDB	PRK15453.
Enzyme and pathway databases
BioCyc	SMED366394:GJAL-3982-MONOMER.
UniPathway	UPA00116.
Family and domain databases
InterPro	IPR006082. PRK. IPR006083. PRK/URK. [Graphical view]
Pfam	PF00485. PRK. 1 hit. [Graphical view]
PRINTS	PR00478. PHRIBLKINASE.
PROSITE	PS00567. PHOSPHORIBULOKINASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

KPPR_SINMW

Accession

Primary (citable) accession number: P56887
Secondary accession number(s): A6UGF1

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 13, 2007
Last modified:	May 1, 2013
This is version 64 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program