P56884 (GLND_RHIME) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:	glnD
Ordered Locus Names:	R00396
ORF Names:	SMc01124

Organism

Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) [Complete proteome] [HAMAP]

Taxonomic identifier

266834 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Sinorhizobium/Ensifer group › Sinorhizobium › Rhizobium meliloti

Protein attributes

Sequence length	949 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein By similarity. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Biological process	Nitrogen fixation
Molecular function	Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: EC amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 949	949	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_0000192760

Sequences

	Sequence		Length	Mass (Da)
	P56884 [UniParc]. Last modified May 30, 2000. Version 1. Checksum: EF549C1B0D8540A0	FASTA	949	106,382
	10 20 30 40 50 60 MARHETSFPE ILDVAALRAR CDFIASAHAE QREPMRRALL AAFKEANVAG RAKARELLAA 70 80 90 100 110 120 DGAGIKCAER ISWLQDQLIT LLHDFVLNQV FDAAKAPEAS RIAVTAVGGY GRGTLAPGSD 130 140 150 160 170 180 IDLLFLLPAK KAVWAEPAIE FMLYILWDLG FKVGHATRTI EECIRLSRAD MTIRTAILEC 190 200 210 220 230 240 RYVCGSAALA NELETRFDHE IVRNTGPEFI AAKLAERDER HRKAGDTRYL VEPNVKEGKG 250 260 270 280 290 300 GLRDLHTLFW ISKYFYRVKD SADLVKLGVL SKQEYKLFQK AEDFLWAVRC HMHFLTGKAE 310 320 330 340 350 360 ERLSFDIQRE IAEALGYHDH PGLSAVERFM KHYFLVAKDV GDLTRIFCSA LEDQQAKDTP 370 380 390 400 410 420 GITGVISRFR NRVRKIAGTL DFVDDGGRIA LAGTDVFKRD PVNLMRLFHI ADINGLEFHP 430 440 450 460 470 480 AALKQVTRSL GLITPHLREN EEANRLFLSI LTSRRNPELI LRRMNEAGVL GRFIPEFGKI 490 500 510 520 530 540 VSMMQFNMYH HYTVDEHLLR SVDVLSRIER GLEEEAHPLT AMLMPGIEDR EALYVAVLLH 550 560 570 580 590 600 DIAKGRPEDH SVAGAKVARK LCPRFRLTPK QTEMVVWLVE EHLTMSMVAQ TRDLNDRKTI 610 620 630 640 650 660 VDFAERVQSL ERLKMLLILT VCDIRAVGPG VWNGWKGQLL RTLYYETELL LSGGFSELSR 670 680 690 700 710 720 KERAKHAAHM LEEALADWPK KERQAYVRLH YQPYLLTVAL EEQVRHAGFI READRAGRTL 730 740 750 760 770 780 ATMVRTHDFH AITEITVLSP DHPRLLTVIA GACAAAGANI VGAQIHTTSD GRALDTILVN 790 800 810 820 830 840 REFSVAEDET RRAASIGKLI EDVLSGRKRL PEVIASRTRV KKRSRAFTVT PEVTISNTLS 850 860 870 880 890 900 NKFTVIEVEG LDRTGLLSEV TAVLSDLSLD IASAHITTFG EKVIDTFYVT DLVGSKITSE 910 920 930 940 NRQMNIAARL KAVLAGEVDE ARERMPSGII APTPVSRVPH GSKTTKAET

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"glnD and mviN are genes of an essential operon in Sinorhizobium meliloti." Rudnick P.A., Arcondeguy T., Kennedy C.K., Kahn D. J. Bacteriol. 183:2682-2685(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Analysis of the chromosome sequence of the legume symbiont Sinorhizobium meliloti strain 1021." Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J., Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S., Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D. , Pohl T., Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C., Thebault P., Vandenbol M., Weidner S., Galibert F. Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.
[3]	"The composite genome of the legume symbiont Sinorhizobium meliloti." Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F., Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G., Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P., Cowie A. , Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S., Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I., Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S., Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C., Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R., Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H., Wong K., Yeh K.-C., Batut J. Science 293:668-672(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 1021.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF227730 Genomic DNA. Translation: AAF37852.1. AL591688 Genomic DNA. Translation: CAC41833.1.
RefSeq	NP_384502.1. NC_003047.1.
3D structure databases
ProteinModelPortal	P56884.
ModBase	Search...
Protein-protein interaction databases
STRING	266834.SMc01124.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAC41833; CAC41833; SMc01124.
GeneID	1232030.
KEGG	sme:SMc01124.
PATRIC	23629999. VBISinMel96828_1769.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2844.
HOGENOM	HOG000261779.
KO	K00990.
OMA	SPKVWNA.
ProtClustDB	PRK05092.
Enzyme and pathway databases
BioCyc	SMEL266834:GJF6-407-MONOMER.
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_RHIME

Accession

Primary (citable) accession number: P56884

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	May 30, 2000
Last modified:	May 29, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program