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Protein

Sjoegren syndrome/scleroderma autoantigen 1 homolog

Gene

Sssca1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Miscellaneous

Two ORFs are contained in the Sssca1 gene, but only this protein is efficiently translated and expressed.

Names & Taxonomyi

Protein namesi
Recommended name:
Sjoegren syndrome/scleroderma autoantigen 1 homolog
Alternative name(s):
Autoantigen p27 homolog
Protein C184L
Gene namesi
Name:Sssca1
Synonyms:C184l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1913482. Sssca1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00000722022 – 199Sjoegren syndrome/scleroderma autoantigen 1 homologAdd BLAST198

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineBy similarity1
Modified residuei94PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiP56873.
PaxDbiP56873.
PeptideAtlasiP56873.
PRIDEiP56873.

PTM databases

iPTMnetiP56873.
PhosphoSitePlusiP56873.

Expressioni

Tissue specificityi

Expressed in the early postnatal brain.1 Publication

Developmental stagei

Expressed in forebrain at E16.1 Publication

Gene expression databases

BgeeiENSMUSG00000079478.
ExpressionAtlasiP56873. baseline and differential.
GenevisibleiP56873. MM.

Interactioni

Protein-protein interaction databases

BioGridi207948. 1 interactor.
IntActiP56873. 3 interactors.
MINTiMINT-218127.
STRINGi10090.ENSMUSP00000025885.

Structurei

3D structure databases

ProteinModelPortaliP56873.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4537. Eukaryota.
ENOG4111RNZ. LUCA.
GeneTreeiENSGT00390000013169.
HOGENOMiHOG000007383.
HOVERGENiHBG054236.
InParanoidiP56873.
OMAiMKVIQAR.
OrthoDBiEOG091G0MMO.
PhylomeDBiP56873.
TreeFamiTF320182.

Family and domain databases

InterProiView protein in InterPro
IPR009563. SSSCA1.
PfamiView protein in Pfam
PF06677. Auto_anti-p27. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P56873-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNGADVDD FTWEPPTEAE TKVLQARRER QDRISRLMGD YLLRGYRMLG
60 70 80 90 100
DTCADCGTIL LQDKQRKIYC VACQELDSDV DKDNPALNAQ AALSQAREHQ
110 120 130 140 150
LASSTEPASS SRPPSQPPVP RPEHCEGAAA GLKAAQAPPL PAAPPNTDAV
160 170 180 190
ASTQTALLQK LTWASVELGS STSLETSIQL CGLIRACAEA LGSLKQLDH
Length:199
Mass (Da):21,336
Last modified:May 30, 2000 - v1
Checksum:i13A5222048009E00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012727 mRNA. Translation: BAA87048.1.
BC021593 mRNA. Translation: AAH21593.1.
CCDSiCCDS29479.1.
RefSeqiNP_065237.3. NM_020491.5.
UniGeneiMm.455818.

Genome annotation databases

EnsembliENSMUST00000025885; ENSMUSP00000025885; ENSMUSG00000079478.
ENSMUST00000160852; ENSMUSP00000125570; ENSMUSG00000079478.
GeneIDi56390.
KEGGimmu:56390.
UCSCiuc008gfd.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiSSA27_MOUSE
AccessioniPrimary (citable) accession number: P56873
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: September 27, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot