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Protein

Sjoegren syndrome/scleroderma autoantigen 1 homolog

Gene

Sssca1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Sjoegren syndrome/scleroderma autoantigen 1 homolog
Alternative name(s):
Autoantigen p27 homolog
Protein C184L
Gene namesi
Name:Sssca1
Synonyms:C184l
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:1913482. Sssca1.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 199198Sjoegren syndrome/scleroderma autoantigen 1 homologPRO_0000072202Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylalanineBy similarity
Modified residuei94 – 941PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiP56873.
PaxDbiP56873.
PRIDEiP56873.

PTM databases

iPTMnetiP56873.
PhosphoSiteiP56873.

Expressioni

Tissue specificityi

Expressed in the early postnatal brain.1 Publication

Developmental stagei

Expressed in forebrain at E16.1 Publication

Gene expression databases

BgeeiP56873.
ExpressionAtlasiP56873. baseline and differential.
GenevisibleiP56873. MM.

Interactioni

Protein-protein interaction databases

IntActiP56873. 3 interactions.
MINTiMINT-218127.
STRINGi10090.ENSMUSP00000025885.

Structurei

3D structure databases

ProteinModelPortaliP56873.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4537. Eukaryota.
ENOG4111RNZ. LUCA.
HOGENOMiHOG000007383.
HOVERGENiHBG054236.
InParanoidiP56873.
OMAiYCVSCQE.
OrthoDBiEOG79SDZN.
PhylomeDBiP56873.
TreeFamiTF320182.

Family and domain databases

InterProiIPR009563. SSSCA1.
[Graphical view]
PfamiPF06677. Auto_anti-p27. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P56873-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALNGADVDD FTWEPPTEAE TKVLQARRER QDRISRLMGD YLLRGYRMLG
60 70 80 90 100
DTCADCGTIL LQDKQRKIYC VACQELDSDV DKDNPALNAQ AALSQAREHQ
110 120 130 140 150
LASSTEPASS SRPPSQPPVP RPEHCEGAAA GLKAAQAPPL PAAPPNTDAV
160 170 180 190
ASTQTALLQK LTWASVELGS STSLETSIQL CGLIRACAEA LGSLKQLDH
Length:199
Mass (Da):21,336
Last modified:May 30, 2000 - v1
Checksum:i13A5222048009E00
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012727 mRNA. Translation: BAA87048.1.
BC021593 mRNA. Translation: AAH21593.1.
CCDSiCCDS29479.1.
RefSeqiNP_065237.3. NM_020491.5.
UniGeneiMm.455818.

Genome annotation databases

EnsembliENSMUST00000025885; ENSMUSP00000025885; ENSMUSG00000079478.
ENSMUST00000160852; ENSMUSP00000125570; ENSMUSG00000079478.
GeneIDi56390.
KEGGimmu:56390.
UCSCiuc008gfd.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB012727 mRNA. Translation: BAA87048.1.
BC021593 mRNA. Translation: AAH21593.1.
CCDSiCCDS29479.1.
RefSeqiNP_065237.3. NM_020491.5.
UniGeneiMm.455818.

3D structure databases

ProteinModelPortaliP56873.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP56873. 3 interactions.
MINTiMINT-218127.
STRINGi10090.ENSMUSP00000025885.

PTM databases

iPTMnetiP56873.
PhosphoSiteiP56873.

Proteomic databases

EPDiP56873.
PaxDbiP56873.
PRIDEiP56873.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025885; ENSMUSP00000025885; ENSMUSG00000079478.
ENSMUST00000160852; ENSMUSP00000125570; ENSMUSG00000079478.
GeneIDi56390.
KEGGimmu:56390.
UCSCiuc008gfd.2. mouse.

Organism-specific databases

CTDi10534.
MGIiMGI:1913482. Sssca1.

Phylogenomic databases

eggNOGiKOG4537. Eukaryota.
ENOG4111RNZ. LUCA.
HOGENOMiHOG000007383.
HOVERGENiHBG054236.
InParanoidiP56873.
OMAiYCVSCQE.
OrthoDBiEOG79SDZN.
PhylomeDBiP56873.
TreeFamiTF320182.

Miscellaneous databases

PROiP56873.
SOURCEiSearch...

Gene expression databases

BgeeiP56873.
ExpressionAtlasiP56873. baseline and differential.
GenevisibleiP56873. MM.

Family and domain databases

InterProiIPR009563. SSSCA1.
[Graphical view]
PfamiPF06677. Auto_anti-p27. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Novel related cDNAs (C184L, C184M, and C184S) from developing mouse brain encoding two apparently unrelated proteins."
    Sakuma-Takagi M., Tohyama Y., Kasama-Yoshida H., Sakagami H., Kondo H., Kurihara T.
    Biochem. Biophys. Res. Commun. 263:737-742(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], DEVELOPMENTAL STAGE, TISSUE SPECIFICITY.
    Strain: ICR.
    Tissue: Forebrain.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Liver.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Spleen and Testis.

Entry informationi

Entry nameiSSA27_MOUSE
AccessioniPrimary (citable) accession number: P56873
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: June 8, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

Two ORFs are contained in the Sssca1 gene, but only this protein is efficiently translated and expressed.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.