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Protein

ATP synthase subunit alpha, chloroplastic

Gene

atpA

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.UniRule annotation

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei363Required for activityUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi170 – 177ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

  • ATP synthesis coupled proton transport Source: InterPro
  • defense response to bacterium Source: TAIR
  • response to cold Source: TAIR

Keywordsi

Molecular functionHydrolase
Biological processATP synthesis, Hydrogen ion transport, Ion transport, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciARA:ATCG00120-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase subunit alpha, chloroplasticUniRule annotation (EC:3.6.3.14UniRule annotation)
Alternative name(s):
ATP synthase F1 sector subunit alphaUniRule annotation
F-ATPase subunit alphaUniRule annotation
Gene namesi
Name:atpAUniRule annotation
Ordered Locus Names:AtCg00120
Encoded oniPlastid; Chloroplast
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chloroplast

Organism-specific databases

AraportiATCG00120
TAIRilocus:504954636 ATCG00120

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CF(1), Chloroplast, Membrane, Plastid, Thylakoid

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001443701 – 507ATP synthase subunit alpha, chloroplasticAdd BLAST507

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei257PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP56757
PRIDEiP56757

2D gel databases

SWISS-2DPAGEiP56757

PTM databases

iPTMnetiP56757

Expressioni

Gene expression databases

ExpressionAtlasiP56757 baseline and differential
GenevisibleiP56757 AT

Interactioni

Subunit structurei

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has four main subunits: a, b, b' and c.UniRule annotation

Protein-protein interaction databases

BioGridi29984, 5 interactors
IntActiP56757, 1 interactor
MINTiP56757
STRINGi3702.ATCG00120.1

Structurei

3D structure databases

ProteinModelPortaliP56757
SMRiP56757
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATPase alpha/beta chains family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1353 Eukaryota
COG0056 LUCA
HOGENOMiHOG000130111
InParanoidiP56757
KOiK02111
OMAiQDKCDSS
OrthoDBiEOG093608VG

Family and domain databases

CDDicd01132 F1_ATPase_alpha, 1 hit
Gene3Di1.20.150.20, 1 hit
2.40.30.20, 1 hit
HAMAPiMF_01346 ATP_synth_alpha_bact, 1 hit
InterProiView protein in InterPro
IPR023366 ATP_synth_asu-like_sf
IPR000793 ATP_synth_asu_C
IPR038376 ATP_synth_asu_C_sf
IPR033732 ATP_synth_F1_a
IPR005294 ATP_synth_F1_asu
IPR020003 ATPase_a/bsu_AS
IPR004100 ATPase_F1/V1/A1_a/bsu_N
IPR036121 ATPase_F1/V1/A1_a/bsu_N_sf
IPR000194 ATPase_F1/V1/A1_a/bsu_nucl-bd
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00006 ATP-synt_ab, 1 hit
PF00306 ATP-synt_ab_C, 1 hit
PF02874 ATP-synt_ab_N, 1 hit
PIRSFiPIRSF039088 F_ATPase_subunit_alpha, 1 hit
SUPFAMiSSF50615 SSF50615, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00962 atpA, 1 hit
PROSITEiView protein in PROSITE
PS00152 ATPASE_ALPHA_BETA, 1 hit

Sequencei

Sequence statusi: Complete.

P56757-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVTIRADEIS NIIRERIEQY NREVTIVNTG TVLQVGDGIA RIYGLDEVMA
60 70 80 90 100
GELVEFEEGT IGIALNLESN NVGVVLMGDG LMIQEGSSVK ATGKIAQIPV
110 120 130 140 150
SEAYLGRVIN ALANPIDGRG KISASESRLI ESPAPGIISR RSVYEPLQTG
160 170 180 190 200
LIAIDSMIPI GRGQRELIIG DRQTGKTAVA TDTILNQQGQ NVICVYVAIG
210 220 230 240 250
QKASSVAQVV TSLQERGAME YTIVVAETAD SPATLQYLAP YTGAALAEYF
260 270 280 290 300
MYREQHTLII YDDLSKQAQA YRQMSLLLRR PPGREAYPGD VFYLHSRLLE
310 320 330 340 350
RAAKLSSQLG EGSMTALPIV ETQSGDVSAY IPTNVISITD GQIFLSADLF
360 370 380 390 400
NAGIRPAINV GISVSRVGSA AQIKAMKQVA GKLKLELAQF AELEAFSQFS
410 420 430 440 450
SDLDKATQNQ LARGQRLREL LKQSQSAPLT VEEQIMTIYT GTNGYLDGLE
460 470 480 490 500
IGQVRKFLVQ LRTYLKTNKP QFQEIIASTK TLTAEAESFL KEGIQEQLER

FLLQEKV
Length:507
Mass (Da):55,328
Last modified:May 30, 2000 - v1
Checksum:i5D48A3CAD6D645C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000423 Genomic DNA Translation: BAA84370.1
RefSeqiNP_051044.1, NC_000932.1

Genome annotation databases

EnsemblPlantsiATCG00120.1; ATCG00120.1; ATCG00120
GeneIDi844790
GrameneiATCG00120.1; ATCG00120.1; ATCG00120
KEGGiath:ArthCp007

Similar proteinsi

Entry informationi

Entry nameiATPA_ARATH
AccessioniPrimary (citable) accession number: P56757
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 30, 2000
Last modified: March 28, 2018
This is version 143 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health