##gff-version 3
P56746	UniProtKB	Chain	1	228	.	.	.	ID=PRO_0000144771;Note=Claudin-15	
P56746	UniProtKB	Topological domain	1	1	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Transmembrane	2	24	.	.	.	Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Topological domain	25	74	.	.	.	Note=Extracellular;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Transmembrane	75	99	.	.	.	Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Topological domain	100	115	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Transmembrane	116	140	.	.	.	Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Topological domain	141	159	.	.	.	Note=Extracellular;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Transmembrane	160	182	.	.	.	Note=Helical;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Topological domain	183	228	.	.	.	Note=Cytoplasmic;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Region	146	147	.	.	.	Note=Important for the formation of tight-junction strand-like structures;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Region	208	228	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P56746	UniProtKB	Site	55	55	.	.	.	Note=Important for Na(+)-selective paracellular ion transport	
P56746	UniProtKB	Site	64	64	.	.	.	Note=Important for Na(+)-selective paracellular ion transport	
P56746	UniProtKB	Site	68	68	.	.	.	Note=Important for the formation of tight-junction strand-like structures;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Modified residue	111	111	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:19690332;Dbxref=PMID:19690332	
P56746	UniProtKB	Modified residue	211	211	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:D3ZQJ0	
P56746	UniProtKB	Modified residue	218	218	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q9Z0S5	
P56746	UniProtKB	Disulfide bond	52	62	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250	
P56746	UniProtKB	Mutagenesis	46	46	.	.	.	Note=No effect on charge selectivity for paracellular ion transport. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12055082;Dbxref=PMID:12055082	
P56746	UniProtKB	Mutagenesis	55	55	.	.	.	Note=Reverses the charge selectivity for paracellular ion transport%2C favoring Cl(-) transport. D->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12055082;Dbxref=PMID:12055082	
P56746	UniProtKB	Mutagenesis	64	64	.	.	.	Note=Impairs the charge selectivity for paracellular ion transport%2C favoring Cl(-) transport. E->K;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12055082;Dbxref=PMID:12055082