Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Seed trypsin/chymotrypsin inhibitor IVB

Gene
N/A
Organism
Pisum sativum (Garden pea)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Inhibitor of trypsin and of chymotrypsin. May function as a natural phytochemical defense against predators.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei16 – 17Reactive bond for trypsin2
Sitei42 – 43Reactive bond for chymotrypsin2

GO - Molecular functioni

Keywordsi

Molecular functionProtease inhibitor, Serine protease inhibitor

Protein family/group databases

MEROPSiI12.018

Names & Taxonomyi

Protein namesi
Recommended name:
Seed trypsin/chymotrypsin inhibitor IVB
Short name:
PSTI-IVB
Cleaved into the following chain:
OrganismiPisum sativum (Garden pea)
Taxonomic identifieri3888 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaeFabeaePisum

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000032751 – 72Seed trypsin/chymotrypsin inhibitor IVBAdd BLAST72
ChainiPRO_00000032761 – 63Seed trypsin/chymotrypsin inhibitor IIAdd BLAST63

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi8 ↔ 61Combined sources1 Publication
Disulfide bondi9 ↔ 24Combined sources1 Publication
Disulfide bondi12 ↔ 57Combined sources1 Publication
Disulfide bondi14 ↔ 22Combined sources1 Publication
Disulfide bondi31 ↔ 38Combined sources1 Publication
Disulfide bondi35 ↔ 50Combined sources1 Publication
Disulfide bondi40 ↔ 48Combined sources1 Publication

Keywords - PTMi

Disulfide bond

Proteomic databases

PRIDEiP56679

Expressioni

Tissue specificityi

Seed.

Developmental stagei

During desiccation stage of seed development increasing activity seems to be associated with appearance of isoform (PSTI II) which has a stronger affinity for trypsin.

Structurei

Secondary structure

172
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi12 – 19Combined sources8
Beta strandi22 – 24Combined sources3
Beta strandi27 – 30Combined sources4
Beta strandi36 – 45Combined sources10
Beta strandi47 – 50Combined sources4
Beta strandi53 – 56Combined sources4
Beta strandi61 – 63Combined sources3
Beta strandi67 – 70Combined sources4

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1PBIX-ray2.70A/B1-72[»]
ProteinModelPortaliP56679
SMRiP56679
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP56679

Family & Domainsi

Sequence similaritiesi

Family and domain databases

CDDicd00023 BBI, 1 hit
InterProiView protein in InterPro
IPR035995 Bowman-Birk_prot_inh
IPR000877 Prot_inh_BBI
PfamiView protein in Pfam
PF00228 Bowman-Birk_leg, 1 hit
SMARTiView protein in SMART
SM00269 BowB, 1 hit
SUPFAMiSSF57247 SSF57247, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P56679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GDDVKSACCD TCLCTKSNPP TCRCVDVGET CHSACLSCIC AYSNPPKCQC
60 70
FDTQKFCYKA CHNSELEEVI KN
Length:72
Mass (Da):7,864
Last modified:May 30, 2000 - v2
Checksum:iF12E71FAAD9A4BF7
GO

Similar proteinsi

Entry informationi

Entry nameiIBBB_PEA
AccessioniPrimary (citable) accession number: P56679
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: May 30, 2000
Last modified: May 23, 2018
This is version 78 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Cookie policy

We would like to use anonymized google analytics cookies to gather statistics on how uniprot.org is used in aggregate. Learn more

UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health