P56628 (RL22B_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
60S ribosomal protein L22-B

Alternative name(s):
L1c
RP4
YL31

Gene names

Name:	RPL22B
Ordered Locus Names:	YFL034C-A
ORF Names:	YFL034BC

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	122 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Subunit structure	Component of the large ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S). Ref.3
Subcellular location	Cytoplasm Ref.4.
Miscellaneous	Present with 74700 molecules/cell in log phase SD medium. Ref.5 There are 2 genes for L22 in yeast.
Sequence similarities	Belongs to the ribosomal protein L22e family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cytoplasmic translation Inferred from direct assay. Source: SGD
Cellular component	cytosolic large ribosomal subunit Inferred from direct assay. Source: SGD
Molecular function	structural constituent of ribosome Inferred from direct assay. Source: SGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 122	121	60S ribosomal protein L22-B		PRO_0000215515

Sequences

	Sequence		Length	Mass (Da)
	P56628 [UniParc]. Last modified January 23, 2007. Version 2. Checksum: 2A21CEBC75C20A6B	FASTA	122	13,827
	10 20 30 40 50 60 MAPNTSRKQK VIKTLTVDVS SPTENGVFDP ASYSKYLIDH IKVDGAVGNL GNAIEVTEDG 70 80 90 100 110 120 SIVTVVSSAK FSGKYLKYLT KKYLKKNQLR DWIRFVSIRQ NQYKLVFYQV TPEDADEEED DE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Analysis of the nucleotide sequence of chromosome VI from Saccharomyces cerevisiae." Murakami Y., Naitou M., Hagiwara H., Shibata T., Ozawa M., Sasanuma S., Sasanuma M., Tsuchiya Y., Soeda E., Yokoyama K., Yamazaki M., Tashiro H., Eki T. Nat. Genet. 10:261-268(1995) [PubMed: 7670463] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[3]	"The list of cytoplasmic ribosomal proteins of Saccharomyces cerevisiae." Planta R.J., Mager W.H. Yeast 14:471-477(1998) [PubMed: 9559554] [Abstract] Cited for: NOMENCLATURE, SUBUNIT.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D50617 Genomic DNA. No translation available. BK006940 Genomic DNA. Translation: DAA12406.1.
PIR	S58649.
RefSeq	NP_116619.1. NM_001184310.1.
3D structure databases
ProteinModelPortal	P56628.
SMR	P56628. Positions 6-110.
ModBase	Search...
Protein-protein interaction databases
STRING	P56628.
Proteomic databases
PeptideAtlas	P56628.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YFL034C-A; YFL034C-A; YFL034C-A.
GeneID	850509.
KEGG	sce:YFL034C-A.
NMPDR	fig|4932.3.peg.2244.
Organism-specific databases
SGD	S000006436. RPL22B.
Phylogenomic databases
eggNOG	fuNOG10743.
GeneTree	EFGT00050000003902.
HOGENOM	HBG716459.
OMA	KYLKKQQ.
OrthoDB	EOG4TF3VZ.
Gene expression databases
ArrayExpress	P56628.
Genevestigator	P56628.
GermOnline	YFL034C-A. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR002671. Ribosomal_L22e. [Graphical view]
KO	K02891.
PANTHER	PTHR10064. Ribosomal_L22e. 1 hit.
Pfam	PF01776. Ribosomal_L22e. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	966221.

Entry information

Entry name

RL22B_YEAST

Accession

Primary (citable) accession number: P56628
Secondary accession number(s): D6VTJ6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
Last sequence update:	January 23, 2007
Last modified:	December 14, 2011
This is version 78 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program