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P56553 (CGR1P_CANAL) Reviewed, UniProtKB/Swiss-Prot

Last modified March 6, 2013. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cell growth-regulated gene 1 protein
Gene names
Name:CGR1
ORF Names:CaO19.10237, CaO19.2722
OrganismCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [Reference proteome]
Taxonomic identifier237561 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › mitosporic Saccharomycetales › Candida ›

Protein attributes

Sequence length340 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the cell growth regulation.

Sequence similarities

Belongs to the SMP-30/CGR1 family.

Ontologies

Keywords
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processnegative regulation of cell growth

Inferred from expression pattern Ref.1. Source: CGD

   Cellular_componentcytoplasm

Inferred from sequence or structural similarity Ref.1. Source: CGD

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 340340Cell growth-regulated gene 1 protein
PRO_0000173051

Natural variations

Natural variant2601D → E in allele CaO19.2722.
Natural variant2661I → N in allele CaO19.2722.
Natural variant2701K → I in allele CaO19.2722.
Natural variant3091I → T in allele CaO19.2722.

Experimental info

Sequence conflict52 – 543INT → TNI in BAA28176. Ref.1
Sequence conflict2061D → N in BAA28176. Ref.1
Sequence conflict2331P → S in BAA28176. Ref.1

Sequences

Sequence LengthMass (Da)Tools
P56553 [UniParc].

Last modified March 6, 2007. Version 2.
Checksum: 4A824993A13ECBF9

FASTA34038,414
        10         20         30         40         50         60 
MSLTITKDNI FPKGYRGRLT EGVTYDERNN TLLWVDIIQG EVHRVFLDNT NINTNTSSSS 

        70         80         90        100        110        120 
HETLKWDSSN ESIGAICLTN DPNKLIICSK YGLAYGDFSS STIEYFFKYP HTTNPDEKLR 

       130        140        150        160        170        180 
LRSNDGIIDP WGNLWIGVMN DFPIGAKEGI QPEGKLYRIG FSKESNKLTC DVMIENSLIS 

       190        200        210        220        230        240 
NGLCFNNQGD EFYWTDSLTF KIWKYDYDKT TNKLTNKSVF IDLKQFYPDV EQPEPDGLVM 

       250        260        270        280        290        300 
TNNGEIYTCV FSTGTILHVD NQGKEIERIK IAAKRPTCVT IGSGIKNNEM FVTTGHLKLD 

       310        320        330        340 
DEKATIDAIN LDGDLGGFLF KLKVDKDLNG QKKNIWGGKV

« Hide

References

« Hide 'large scale' references
[1]"Isolation and expression of a gene (CGR1) regulated during the yeast-hyphal transition in Candida albicans."
Cho T., Sudoh M., Tanaka T., Nakashima Y., Chibana H., Kaminishi Y.
Biochim. Biophys. Acta 1517:288-292(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: JCM 9061.
[2]"The diploid genome sequence of Candida albicans."
Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W., Scherer S.
Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: SC5314 / ATCC MYA-2876.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB013716 Genomic DNA. Translation: BAA28176.1.
AACQ01000023 Genomic DNA. Translation: EAL01632.1.
AACQ01000025 Genomic DNA. Translation: EAL01393.1.
RefSeqXP_720242.1. XM_715149.1.
XP_720472.1. XM_715379.1.

3D structure databases

ProteinModelPortalP56553.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3637853.
3638105.
KEGGcal:CaO19.10237.
cal:CaO19.2722.

Organism-specific databases

CGDCAL0065228. CGR1.

Phylogenomic databases

eggNOGCOG3386.

Family and domain databases

Gene3D2.120.10.30. 1 hit.
InterProIPR011042. 6-blade_b-propeller_TolB-like.
IPR013658. SGL.
IPR005511. SMP-30.
[Graphical view]
PfamPF08450. SGL. 1 hit.
[Graphical view]
PRINTSPR01790. SMP30FAMILY.
ProtoNetSearch...

Entry information

Entry nameCGR1P_CANAL
AccessionPrimary (citable) accession number: P56553
Secondary accession number(s): Q5AF85, Q5AFX1
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: March 6, 2007
Last modified: March 6, 2013
This is version 55 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Candida albicans

Candida albicans: entries and gene names

SIMILARITY comments

Index of protein domains and families

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