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P56553

- CGR1P_CANAL

UniProt

P56553 - CGR1P_CANAL

Protein

Cell growth-regulated gene 1 protein

Gene

CGR1

Organism
Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 59 (01 Oct 2014)
      Sequence version 2 (06 Mar 2007)
      Previous versions | rss
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    Functioni

    Involved in the cell growth regulation.

    GO - Biological processi

    1. negative regulation of cell growth Source: CGD

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cell growth-regulated gene 1 protein
    Gene namesi
    Name:CGR1
    ORF Names:CaO19.10237, CaO19.2722
    OrganismiCandida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
    Taxonomic identifieri237561 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida
    ProteomesiUP000000559: Unassembled WGS sequence

    Organism-specific databases

    CGDiCAL0065228. CGR1.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: CGD

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 340340Cell growth-regulated gene 1 proteinPRO_0000173051Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    BioGridi1220947. 1 interaction.
    STRINGi5476.CAL0004197.

    Structurei

    3D structure databases

    ProteinModelPortaliP56553.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SMP-30/CGR1 family.Curated

    Phylogenomic databases

    eggNOGiCOG3386.
    OrthoDBiEOG78H43X.

    Family and domain databases

    Gene3Di2.120.10.30. 1 hit.
    InterProiIPR011042. 6-blade_b-propeller_TolB-like.
    IPR013658. SGL.
    IPR005511. SMP-30.
    [Graphical view]
    PfamiPF08450. SGL. 1 hit.
    [Graphical view]
    PRINTSiPR01790. SMP30FAMILY.

    Sequencei

    Sequence statusi: Complete.

    P56553-1 [UniParc]FASTAAdd to Basket

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    MSLTITKDNI FPKGYRGRLT EGVTYDERNN TLLWVDIIQG EVHRVFLDNT    50
    NINTNTSSSS HETLKWDSSN ESIGAICLTN DPNKLIICSK YGLAYGDFSS 100
    STIEYFFKYP HTTNPDEKLR LRSNDGIIDP WGNLWIGVMN DFPIGAKEGI 150
    QPEGKLYRIG FSKESNKLTC DVMIENSLIS NGLCFNNQGD EFYWTDSLTF 200
    KIWKYDYDKT TNKLTNKSVF IDLKQFYPDV EQPEPDGLVM TNNGEIYTCV 250
    FSTGTILHVD NQGKEIERIK IAAKRPTCVT IGSGIKNNEM FVTTGHLKLD 300
    DEKATIDAIN LDGDLGGFLF KLKVDKDLNG QKKNIWGGKV 340
    Length:340
    Mass (Da):38,414
    Last modified:March 6, 2007 - v2
    Checksum:i4A824993A13ECBF9
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti52 – 543INT → TNI in BAA28176. (PubMed:11342110)Curated
    Sequence conflicti206 – 2061D → N in BAA28176. (PubMed:11342110)Curated
    Sequence conflicti233 – 2331P → S in BAA28176. (PubMed:11342110)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti260 – 2601D → E in allele CaO19.2722.
    Natural varianti266 – 2661I → N in allele CaO19.2722.
    Natural varianti270 – 2701K → I in allele CaO19.2722.
    Natural varianti309 – 3091I → T in allele CaO19.2722.

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB013716 Genomic DNA. Translation: BAA28176.1.
    AACQ01000023 Genomic DNA. Translation: EAL01632.1.
    AACQ01000025 Genomic DNA. Translation: EAL01393.1.
    RefSeqiXP_720242.1. XM_715149.1.
    XP_720472.1. XM_715379.1.

    Genome annotation databases

    GeneIDi3637853.
    3638105.
    KEGGical:CaO19.10237.
    cal:CaO19.2722.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AB013716 Genomic DNA. Translation: BAA28176.1 .
    AACQ01000023 Genomic DNA. Translation: EAL01632.1 .
    AACQ01000025 Genomic DNA. Translation: EAL01393.1 .
    RefSeqi XP_720242.1. XM_715149.1.
    XP_720472.1. XM_715379.1.

    3D structure databases

    ProteinModelPortali P56553.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 1220947. 1 interaction.
    STRINGi 5476.CAL0004197.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 3637853.
    3638105.
    KEGGi cal:CaO19.10237.
    cal:CaO19.2722.

    Organism-specific databases

    CGDi CAL0065228. CGR1.

    Phylogenomic databases

    eggNOGi COG3386.
    OrthoDBi EOG78H43X.

    Family and domain databases

    Gene3Di 2.120.10.30. 1 hit.
    InterProi IPR011042. 6-blade_b-propeller_TolB-like.
    IPR013658. SGL.
    IPR005511. SMP-30.
    [Graphical view ]
    Pfami PF08450. SGL. 1 hit.
    [Graphical view ]
    PRINTSi PR01790. SMP30FAMILY.
    ProtoNeti Search...

    Publicationsi

    1. "Isolation and expression of a gene (CGR1) regulated during the yeast-hyphal transition in Candida albicans."
      Cho T., Sudoh M., Tanaka T., Nakashima Y., Chibana H., Kaminishi Y.
      Biochim. Biophys. Acta 1517:288-292(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: JCM 9061.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SC5314 / ATCC MYA-2876.

    Entry informationi

    Entry nameiCGR1P_CANAL
    AccessioniPrimary (citable) accession number: P56553
    Secondary accession number(s): Q5AF85, Q5AFX1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: March 6, 2007
    Last modified: October 1, 2014
    This is version 59 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Candida albicans
      Candida albicans: entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3