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Protein

Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

Gene

IDH3B

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
Biological processTricarboxylic acid cycle
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (EC:1.1.1.41)
Alternative name(s):
Isocitric dehydrogenase subunit beta
NAD(+)-specific ICDH subunit beta
Gene namesi
Name:IDH3B
OrganismiSus scrofa (Pig)
Taxonomic identifieri9823 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaSuinaSuidaeSus
Proteomesi
  • UP000008227 Componenti: Unplaced

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000835911 – 103Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialAdd BLAST103

Proteomic databases

PaxDbiP56472.
PeptideAtlasiP56472.
PRIDEiP56472.

Interactioni

Subunit structurei

Heterooligomer of subunits alpha, beta, and gamma in the apparent ratio of 2:1:1.

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000007635.

Structurei

3D structure databases

ProteinModelPortaliP56472.
SMRiP56472.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG0784. Eukaryota.
COG0473. LUCA.
InParanoidiP56472.

Sequencei

Sequence statusi: Fragments.

P56472-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
ASRSQAEDVR VEGAFPVTML PGDGVGPELM AAVGVIECLK LGDGLFLQCC
60 70 80 90 100
EEVAELYPKN IANPTATLLA SCMMLDHLKT SDMGGYATCQ DFTEAVIGAL

SHP
Length:103
Mass (Da):10,803
Last modified:July 15, 1998 - v1
Checksum:i83D811D29EA7756B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-adjacent residuesi33 – 34Curated2
Non-adjacent residuesi40 – 41Curated2
Non-adjacent residuesi59 – 60Curated2
Non-adjacent residuesi79 – 80Curated2

Sequence databases

PIRiB35834.
UniGeneiSsc.3464.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiIDH3B_PIG
AccessioniPrimary (citable) accession number: P56472
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: May 10, 2017
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families