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P56464

- ACP_HELPY

UniProt

P56464 - ACP_HELPY

Protein

Acyl carrier protein

Gene

acpP

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Carrier of the growing fatty acid chain in fatty acid biosynthesis.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Biological processi

    Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism

    Enzyme and pathway databases

    UniPathwayiUPA00094.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Acyl carrier proteinUniRule annotation
    Short name:
    ACPUniRule annotation
    Gene namesi
    Name:acpPUniRule annotation
    Ordered Locus Names:HP_0559
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 7878Acyl carrier proteinPRO_0000180144Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei36 – 361O-(pantetheine 4'-phosphoryl)serineUniRule annotation

    Post-translational modificationi

    4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.UniRule annotation

    Keywords - PTMi

    Phosphopantetheine, Phosphoprotein

    Proteomic databases

    PRIDEiP56464.

    Interactioni

    Protein-protein interaction databases

    IntActiP56464. 4 interactions.
    STRINGi85962.HP0559.

    Structurei

    3D structure databases

    ProteinModelPortaliP56464.
    SMRiP56464. Positions 2-74.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 acyl carrier domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0236.
    KOiK02078.
    OMAiVNAEDAF.
    OrthoDBiEOG6MWNJM.

    Family and domain databases

    Gene3Di1.10.1200.10. 1 hit.
    HAMAPiMF_01217. Acyl_carrier.
    InterProiIPR003231. Acyl_carrier.
    IPR009081. Acyl_carrier_prot-like.
    IPR006162. PPantetheine_attach_site.
    [Graphical view]
    PfamiPF00550. PP-binding. 1 hit.
    [Graphical view]
    ProDomiPD000887. PD000887. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    SUPFAMiSSF47336. SSF47336. 1 hit.
    TIGRFAMsiTIGR00517. acyl_carrier. 1 hit.
    PROSITEiPS50075. ACP_DOMAIN. 1 hit.
    PS00012. PHOSPHOPANTETHEINE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P56464-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALFEDIQAV IAEQLNVDAV QVTPEAEFVK DLGADSLDVV ELIMALEEKF   50
    GVEIPDEQAE KIINVGDVVK YIEDNKLA 78
    Length:78
    Mass (Da):8,590
    Last modified:July 15, 1998 - v1
    Checksum:i5DA351914F6DCF09
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07626.1.
    PIRiG64589.
    RefSeqiNP_207354.1. NC_000915.1.
    YP_006934482.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD07626; AAD07626; HP_0559.
    GeneIDi13869750.
    900011.
    KEGGiheo:C694_02890.
    hpy:HP0559.
    PATRICi20592393. VBIHelPyl33062_0585.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07626.1 .
    PIRi G64589.
    RefSeqi NP_207354.1. NC_000915.1.
    YP_006934482.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali P56464.
    SMRi P56464. Positions 2-74.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P56464. 4 interactions.
    STRINGi 85962.HP0559.

    Proteomic databases

    PRIDEi P56464.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD07626 ; AAD07626 ; HP_0559 .
    GeneIDi 13869750.
    900011.
    KEGGi heo:C694_02890.
    hpy:HP0559.
    PATRICi 20592393. VBIHelPyl33062_0585.

    Phylogenomic databases

    eggNOGi COG0236.
    KOi K02078.
    OMAi VNAEDAF.
    OrthoDBi EOG6MWNJM.

    Enzyme and pathway databases

    UniPathwayi UPA00094 .

    Family and domain databases

    Gene3Di 1.10.1200.10. 1 hit.
    HAMAPi MF_01217. Acyl_carrier.
    InterProi IPR003231. Acyl_carrier.
    IPR009081. Acyl_carrier_prot-like.
    IPR006162. PPantetheine_attach_site.
    [Graphical view ]
    Pfami PF00550. PP-binding. 1 hit.
    [Graphical view ]
    ProDomi PD000887. PD000887. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    SUPFAMi SSF47336. SSF47336. 1 hit.
    TIGRFAMsi TIGR00517. acyl_carrier. 1 hit.
    PROSITEi PS50075. ACP_DOMAIN. 1 hit.
    PS00012. PHOSPHOPANTETHEINE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiACP_HELPY
    AccessioniPrimary (citable) accession number: P56464
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: July 15, 1998
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3