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P56463 (DEOD_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Purine nucleoside phosphorylase DeoD-type

Short name=PNP
EC=2.4.2.1
Gene names
Name:deoD
Ordered Locus Names:HP_1178
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length233 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate. HAMAP-Rule MF_01627

Subunit structure

Homohexamer By similarity. HAMAP-Rule MF_01627

Sequence similarities

Belongs to the PNP/UDP phosphorylase family.

Ontologies

Keywords
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpurine nucleoside metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionpurine-nucleoside phosphorylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 233233Purine nucleoside phosphorylase DeoD-type HAMAP-Rule MF_01627
PRO_0000063137

Sequences

Sequence LengthMass (Da)Tools
P56463 [UniParc].

Last modified July 15, 1998. Version 1.
Checksum: 1E44E717F8BDAC9D

FASTA23325,786
        10         20         30         40         50         60 
MTPHINAKIG DFYPQCLLCG DPLRVSYIAK KFLQDAKEIT NVRNMLGFSG KYKGRGISLM 

        70         80         90        100        110        120 
GHGMGIASCT IYVTELIKTY QVKELLRIGT CGAISPKVGL KDIIMATGAS TDSKTNRVRF 

       130        140        150        160        170        180 
LNHDLSATPD FELSLRAYQT AKRLGIDLKV GNVFSSDFFY SFETHAFDLM AKYNHLAIEM 

       190        200        210        220        230 
EAAGLYATAM ELNAKALCLC SVSDHLITKE ALSPKERVES FDNMIILALE MMS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD08222.1.
PIRB64667.
RefSeqNP_207969.1. NC_000915.1.
YP_006935096.1. NC_018939.1.

3D structure databases

ProteinModelPortalP56463.
SMRP56463. Positions 1-231.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP56463. 1 interaction.
STRING85962.HP1178.

Proteomic databases

PRIDEP56463.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD08222; AAD08222; HP_1178.
GeneID899938.
KEGGheo:C694_06090.
hpy:HP1178.
PATRIC20593709. VBIHelPyl33062_1233.

Phylogenomic databases

eggNOGCOG0813.
KOK03784.
OMAYMNAAEA.
OrthoDBEOG6BKJC5.

Enzyme and pathway databases

BioCycHPY:HP1178-MONOMER.

Family and domain databases

Gene3D3.40.50.1580. 1 hit.
HAMAPMF_01627. Pur_nucleosid_phosp.
InterProIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERPTHR21234. PTHR21234. 1 hit.
PfamPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMSSF53167. SSF53167. 1 hit.
TIGRFAMsTIGR00107. deoD. 1 hit.
PROSITEPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDEOD_HELPY
AccessionPrimary (citable) accession number: P56463
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: July 15, 1998
Last modified: July 9, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names