P56421 (MOG_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Molybdopterin adenylyltransferase
Short name=MPT adenylyltransferase
EC=2.7.7.75

Gene names

Name:	mog
Synonyms:	mogA
Ordered Locus Names:	HP_0799

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › delta/epsilon subdivisions › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter › Helicobacter pylori

Protein attributes

Sequence length	176 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the adenylation of molybdopterin as part of the biosynthesis of the molybdenum-cofactor By similarity.
Catalytic activity	ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.
Pathway	Cofactor biosynthesis; molybdopterin biosynthesis.
Sequence similarities	Belongs to the MoaB/Mog family.

Ontologies

Keywords
Biological process	Molybdenum cofactor biosynthesis
Ligand	ATP-binding Nucleotide-binding
Molecular function	Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	Mo-molybdopterin cofactor biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 176	176	Molybdopterin adenylyltransferase		PRO_0000170985

Sequences

	Sequence		Length	Mass (Da)
	P56421 [UniParc]. Last modified July 15, 1998. Version 1. Checksum: 9E244CC047172703	FASTA	176	19,677
	10 20 30 40 50 60 MQTIHIGVLS ASDRASKGIY EDLSGKAIQE VLSEYLLNPL EFYYEIVADE RDLIEKSLIK 70 80 90 100 110 120 MCDEYQCDLV VTTGGTGPAL RDITPEATEK VCQKMLPGFG ELMRMTSLKY VPTAILSRQS 130 140 150 160 170 AGIRNKSLII NLPGKPKSIR ECLEAVFPAI PYCVDLILGN YMQVNEKNIQ AFRPKQ

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD07849.1.
PIR	G64619.
RefSeq	NP_207592.1. NC_000915.1. YP_006934713.1. NC_018939.1.
3D structure databases
ProteinModelPortal	P56421.
SMR	P56421. Positions 6-175.
ModBase	Search...
Protein-protein interaction databases
STRING	85962.HP0799.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAD07849; AAD07849; HP_0799.
GeneID	13869982. 899350.
KEGG	heo:C694_04095. hpy:HP0799.
PATRIC	20592885. VBIHelPyl33062_0831.
Phylogenomic databases
eggNOG	COG0521.
KO	K03831.
OMA	VKAFRPK.
ProtClustDB	PRK09417.
Enzyme and pathway databases
UniPathway	UPA00344.
Family and domain databases
Gene3D	3.40.980.10. 1 hit.
InterPro	IPR020817. Mo_cofactor_synthesis. IPR008284. MoCF_biosynth_CS. IPR001453. Mopterin-bd_dom. [Graphical view]
Pfam	PF00994. MoCF_biosynth. 1 hit. [Graphical view]
SMART	SM00852. MoCF_biosynth. 1 hit. [Graphical view]
SUPFAM	SSF53218. MoCF_biosynth. 1 hit.
TIGRFAMs	TIGR00177. molyb_syn. 1 hit.
PROSITE	PS01078. MOCF_BIOSYNTHESIS_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MOG_HELPY

Accession

Primary (citable) accession number: P56421

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	July 15, 1998
Last modified:	May 1, 2013
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program