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P56262

- DLHH_ECOLI

UniProt

P56262 - DLHH_ECOLI

Protein

Putative carboxymethylenebutenolidase

Gene

ysgA

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 3 (11 Oct 2004)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    4-carboxymethylenebut-2-en-4-olide + H2O = 4-oxohex-2-enedioate.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei147 – 1471By similarity
    Active sitei204 – 2041By similarity
    Active sitei236 – 2361By similarity

    GO - Molecular functioni

    1. carboxymethylenebutenolidase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciEcoCyc:G7804-MONOMER.
    ECOL316407:JW5853-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Putative carboxymethylenebutenolidase (EC:3.1.1.45)
    Alternative name(s):
    Dienelactone hydrolase
    Short name:
    DLH
    Gene namesi
    Name:ysgA
    Ordered Locus Names:b3830, JW5853
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG14321. ysgA.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 271271Putative carboxymethylenebutenolidasePRO_0000161578Add
    BLAST

    Proteomic databases

    PaxDbiP56262.
    PRIDEiP56262.

    Expressioni

    Gene expression databases

    GenevestigatoriP56262.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-12929N.
    STRINGi511145.b3830.

    Structurei

    3D structure databases

    ProteinModelPortaliP56262.
    SMRiP56262. Positions 26-265.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the dienelactone hydrolase family.Curated

    Phylogenomic databases

    eggNOGiCOG0412.
    HOGENOMiHOG000157123.
    KOiK01061.
    OMAiCWGGRIS.
    OrthoDBiEOG64FKC2.
    PhylomeDBiP56262.

    Family and domain databases

    Gene3Di3.40.50.1820. 1 hit.
    InterProiIPR029058. AB_hydrolase.
    IPR002925. Dienelactn_hydro.
    [Graphical view]
    PfamiPF01738. DLH. 1 hit.
    [Graphical view]
    SUPFAMiSSF53474. SSF53474. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P56262-1 [UniParc]FASTAAdd to Basket

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    MATTQQSGFA PAASPLASTI VQTPDDAIVA GFTSIPSQGD NMPAYHARPK    50
    QSDGPLPVVI VVQEIFGVHE HIRDICRRLA LEGYLAIAPE LYFREGDPND 100
    FADIPTLLSG LVAKVPDSQV LADLDHVASW ASRNGGDVHR LMITGFCWGG 150
    RITWLYAAHN PQLKAAVAWY GKLTGDKSLN SPKQPVDIAT DLNAPILGLY 200
    GGQDNSIPQE SVETMRQALR AANAKAEIIV YPDAGHAFNA DYRPSYHAAS 250
    AEDGWQRMLE WFKQYGGKKS L 271
    Length:271
    Mass (Da):29,425
    Last modified:October 11, 2004 - v3
    Checksum:iCD05EAD376CD794F
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAT48226.1.
    AP009048 Genomic DNA. Translation: BAE77471.1.
    RefSeqiYP_026268.1. NC_000913.3.
    YP_491612.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAT48226; AAT48226; b3830.
    BAE77471; BAE77471; BAE77471.
    GeneIDi12930484.
    948320.
    KEGGiecj:Y75_p3348.
    eco:b3830.
    PATRICi32123161. VBIEscCol129921_3946.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00096 Genomic DNA. Translation: AAT48226.1 .
    AP009048 Genomic DNA. Translation: BAE77471.1 .
    RefSeqi YP_026268.1. NC_000913.3.
    YP_491612.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P56262.
    SMRi P56262. Positions 26-265.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-12929N.
    STRINGi 511145.b3830.

    Proteomic databases

    PaxDbi P56262.
    PRIDEi P56262.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAT48226 ; AAT48226 ; b3830 .
    BAE77471 ; BAE77471 ; BAE77471 .
    GeneIDi 12930484.
    948320.
    KEGGi ecj:Y75_p3348.
    eco:b3830.
    PATRICi 32123161. VBIEscCol129921_3946.

    Organism-specific databases

    EchoBASEi EB4067.
    EcoGenei EG14321. ysgA.

    Phylogenomic databases

    eggNOGi COG0412.
    HOGENOMi HOG000157123.
    KOi K01061.
    OMAi CWGGRIS.
    OrthoDBi EOG64FKC2.
    PhylomeDBi P56262.

    Enzyme and pathway databases

    BioCyci EcoCyc:G7804-MONOMER.
    ECOL316407:JW5853-MONOMER.

    Miscellaneous databases

    PROi P56262.

    Gene expression databases

    Genevestigatori P56262.

    Family and domain databases

    Gene3Di 3.40.50.1820. 1 hit.
    InterProi IPR029058. AB_hydrolase.
    IPR002925. Dienelactn_hydro.
    [Graphical view ]
    Pfami PF01738. DLH. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53474. SSF53474. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    2. Cited for: SEQUENCE REVISION.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.

    Entry informationi

    Entry nameiDLHH_ECOLI
    AccessioniPrimary (citable) accession number: P56262
    Secondary accession number(s): Q2M8D5, Q6BEY8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: October 11, 2004
    Last modified: October 1, 2014
    This is version 91 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3