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P56210 (RL11_GEOSE) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 86. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L11
Gene names
Name:rplK
OrganismGeobacillus stearothermophilus (Bacillus stearothermophilus)
Taxonomic identifier1422 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

Protein attributes

Sequence length133 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. HAMAP-Rule MF_00736

Subunit structure

Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which 2 L12 dimers bind in a sequential fashion forming a pentameric L10(L12)2(L12)2 complex.

Post-translational modification

One or more lysine residues are methylated By similarity. HAMAP-Rule MF_00736

Sequence similarities

Belongs to the ribosomal protein L11P family.

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   PTMMethylation
   Technical term3D-structure
Direct protein sequencing
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

structural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 133›13350S ribosomal protein L11 HAMAP-Rule MF_00736
PRO_0000104244

Experimental info

Non-terminal residue11

Secondary structure

................... 133
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P56210 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 2F0DAC76EFD4AAE1

FASTA13314,103
        10         20         30         40         50         60 
MKLQIPAGKA NPAPPVGPAL GQAGVNIMAF CKEFNARTAD QAGLIIPVEI TVFEDRSFTF 

        70         80         90        100        110        120 
ITKTPPAAVL LKKAAGIESG SGEPNRNKVA TIKRDKVREI AELKMPDLNA ASIEAAMRMI 

       130 
EGTARSMGIV VED 

« Hide

References

[1]"Stabilization of a ribosomal RNA tertiary structure by ribosomal protein L11."
Xing Y., Draper D.E.
J. Mol. Biol. 249:319-331(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.
[2]"Crystal structure of a conserved ribosomal protein-RNA complex."
Conn G.L., Draper D.E., Lattman E.E., Gittis A.G.
Science 284:1171-1174(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 63-129.
[3]"High resolution solution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA."
Markus M.A., Hinck A.P., Huang S., Draper D.E., Torchia D.A.
Nat. Struct. Biol. 4:70-77(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY NMR OF 59-133.
[4]"Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit."
Ban N., Nissen P., Hansen J., Capel M., Moore P.B., Steitz T.A.
Nature 400:841-847(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: 3D-STRUCTURE MODELING OF 63-129 ONTO THE H.MARISMORTUI 50S RIBOSOME.
+Additional computationally mapped references.

Cross-references

Sequence databases

PIRS55555.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1ACINMR-A59-133[»]
1FOWNMR-A59-133[»]
1FOXNMR-A59-133[»]
1FOYNMR-A59-133[»]
1HC8X-ray2.80A/B58-132[»]
1IP8model-G-[»]
1QA6X-ray2.80A/B63-129[»]
1Y39X-ray2.80A/B58-133[»]
2FOWNMR-A59-133[»]
DisProtDP00512.
ProteinModelPortalP56210.
SMRP56210. Positions 1-133.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP56210.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPMF_00736. Ribosomal_L11.
InterProIPR000911. Ribosomal_L11/L12.
IPR006519. Ribosomal_L11_bac-typ.
IPR020783. Ribosomal_L11_C.
IPR020785. Ribosomal_L11_CS.
IPR020784. Ribosomal_L11_N.
[Graphical view]
PANTHERPTHR11661. PTHR11661. 1 hit.
PfamPF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]
SMARTSM00649. RL11. 1 hit.
[Graphical view]
SUPFAMSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
TIGRFAMsTIGR01632. L11_bact. 1 hit.
PROSITEPS00359. RIBOSOMAL_L11. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceP56210.

Entry information

Entry nameRL11_GEOSE
AccessionPrimary (citable) accession number: P56210
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: February 19, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references