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P56210

- RL11_GEOSE

UniProt

P56210 - RL11_GEOSE

Protein

50S ribosomal protein L11

Gene

rplK

Organism
Geobacillus stearothermophilus (Bacillus stearothermophilus)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.

    GO - Molecular functioni

    1. rRNA binding Source: UniProtKB-KW
    2. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Keywords - Ligandi

    RNA-binding, rRNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    50S ribosomal protein L11UniRule annotation
    Gene namesi
    Name:rplKUniRule annotation
    OrganismiGeobacillus stearothermophilus (Bacillus stearothermophilus)
    Taxonomic identifieri1422 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeGeobacillus

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 133›13350S ribosomal protein L11PRO_0000104244Add
    BLAST

    Post-translational modificationi

    One or more lysine residues are methylated.UniRule annotation

    Keywords - PTMi

    Methylation

    Proteomic databases

    PRIDEiP56210.

    Interactioni

    Subunit structurei

    Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which 2 L12 dimers bind in a sequential fashion forming a pentameric L10(L12)2(L12)2 complex.

    Structurei

    Secondary structure

    1
    133
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi61 – 644
    Helixi67 – 759
    Beta strandi77 – 793
    Turni84 – 863
    Beta strandi90 – 923
    Helixi94 – 10310
    Helixi105 – 1073
    Helixi113 – 12715
    Beta strandi129 – 1313

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1ACINMR-A59-133[»]
    1FOWNMR-A59-133[»]
    1FOXNMR-A59-133[»]
    1FOYNMR-A59-133[»]
    1HC8X-ray2.80A/B58-132[»]
    1IP8model-G-[»]
    1QA6X-ray2.80A/B63-129[»]
    1Y39X-ray2.80A/B58-133[»]
    2FOWNMR-A59-133[»]
    DisProtiDP00512.
    ProteinModelPortaliP56210.
    SMRiP56210. Positions 1-133.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiP56210.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L11P family.UniRule annotation

    Family and domain databases

    Gene3Di1.10.10.250. 1 hit.
    3.30.1550.10. 1 hit.
    HAMAPiMF_00736. Ribosomal_L11.
    InterProiIPR000911. Ribosomal_L11/L12.
    IPR006519. Ribosomal_L11_bac-typ.
    IPR020783. Ribosomal_L11_C.
    IPR020785. Ribosomal_L11_CS.
    IPR020784. Ribosomal_L11_N.
    [Graphical view]
    PANTHERiPTHR11661. PTHR11661. 1 hit.
    PfamiPF00298. Ribosomal_L11. 1 hit.
    PF03946. Ribosomal_L11_N. 1 hit.
    [Graphical view]
    SMARTiSM00649. RL11. 1 hit.
    [Graphical view]
    SUPFAMiSSF46906. SSF46906. 1 hit.
    SSF54747. SSF54747. 1 hit.
    TIGRFAMsiTIGR01632. L11_bact. 1 hit.
    PROSITEiPS00359. RIBOSOMAL_L11. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P56210-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKLQIPAGKA NPAPPVGPAL GQAGVNIMAF CKEFNARTAD QAGLIIPVEI    50
    TVFEDRSFTF ITKTPPAAVL LKKAAGIESG SGEPNRNKVA TIKRDKVREI 100
    AELKMPDLNA ASIEAAMRMI EGTARSMGIV VED 133
    Length:133
    Mass (Da):14,103
    Last modified:November 1, 1997 - v1
    Checksum:i2F0DAC76EFD4AAE1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    PIRiS55555.

    Cross-referencesi

    Sequence databases

    PIRi S55555.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1ACI NMR - A 59-133 [» ]
    1FOW NMR - A 59-133 [» ]
    1FOX NMR - A 59-133 [» ]
    1FOY NMR - A 59-133 [» ]
    1HC8 X-ray 2.80 A/B 58-132 [» ]
    1IP8 model - G - [» ]
    1QA6 X-ray 2.80 A/B 63-129 [» ]
    1Y39 X-ray 2.80 A/B 58-133 [» ]
    2FOW NMR - A 59-133 [» ]
    DisProti DP00512.
    ProteinModelPortali P56210.
    SMRi P56210. Positions 1-133.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P56210.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Miscellaneous databases

    EvolutionaryTracei P56210.

    Family and domain databases

    Gene3Di 1.10.10.250. 1 hit.
    3.30.1550.10. 1 hit.
    HAMAPi MF_00736. Ribosomal_L11.
    InterProi IPR000911. Ribosomal_L11/L12.
    IPR006519. Ribosomal_L11_bac-typ.
    IPR020783. Ribosomal_L11_C.
    IPR020785. Ribosomal_L11_CS.
    IPR020784. Ribosomal_L11_N.
    [Graphical view ]
    PANTHERi PTHR11661. PTHR11661. 1 hit.
    Pfami PF00298. Ribosomal_L11. 1 hit.
    PF03946. Ribosomal_L11_N. 1 hit.
    [Graphical view ]
    SMARTi SM00649. RL11. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46906. SSF46906. 1 hit.
    SSF54747. SSF54747. 1 hit.
    TIGRFAMsi TIGR01632. L11_bact. 1 hit.
    PROSITEi PS00359. RIBOSOMAL_L11. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Stabilization of a ribosomal RNA tertiary structure by ribosomal protein L11."
      Xing Y., Draper D.E.
      J. Mol. Biol. 249:319-331(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PARTIAL PROTEIN SEQUENCE.
    2. "Crystal structure of a conserved ribosomal protein-RNA complex."
      Conn G.L., Draper D.E., Lattman E.E., Gittis A.G.
      Science 284:1171-1174(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.8 ANGSTROMS) OF 63-129.
    3. "High resolution solution structure of ribosomal protein L11-C76, a helical protein with a flexible loop that becomes structured upon binding to RNA."
      Markus M.A., Hinck A.P., Huang S., Draper D.E., Torchia D.A.
      Nat. Struct. Biol. 4:70-77(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: STRUCTURE BY NMR OF 59-133.
    4. "Placement of protein and RNA structures into a 5 A-resolution map of the 50S ribosomal subunit."
      Ban N., Nissen P., Hansen J., Capel M., Moore P.B., Steitz T.A.
      Nature 400:841-847(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: 3D-STRUCTURE MODELING OF 63-129 ONTO THE H.MARISMORTUI 50S RIBOSOME.

    Entry informationi

    Entry nameiRL11_GEOSE
    AccessioniPrimary (citable) accession number: P56210
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Direct protein sequencing

    Documents

    1. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3