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Protein

Myoglobin

Gene

MB

Organism
Caretta caretta (Loggerhead sea turtle)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi65 – 651Iron (heme distal ligand)1 Publication
Metal bindingi94 – 941Iron (heme proximal ligand)Combined sources1 Publication

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Muscle protein

Keywords - Biological processi

Oxygen transport, Transport

Keywords - Ligandi

Heme, Iron, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Myoglobin
Gene namesi
Name:MB
OrganismiCaretta caretta (Loggerhead sea turtle)
Taxonomic identifieri8467 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaTestudinesCryptodiraDurocryptodiraAmerichelydiaChelonioideaCheloniidaeCaretta

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 154153MyoglobinPRO_0000053380Add
BLAST

Proteomic databases

PRIDEiP56208.

Structurei

Secondary structure

1
154
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi5 – 1814Combined sources
Helixi19 – 213Combined sources
Helixi22 – 3615Combined sources
Helixi38 – 414Combined sources
Helixi45 – 473Combined sources
Helixi53 – 575Combined sources
Helixi60 – 7718Combined sources
Turni78 – 814Combined sources
Helixi84 – 9613Combined sources
Helixi102 – 11918Combined sources
Turni121 – 1233Combined sources
Helixi126 – 14823Combined sources
Turni149 – 1513Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1LHSX-ray2.00A2-154[»]
1LHTX-ray2.00A2-154[»]
ProteinModelPortaliP56208.
SMRiP56208. Positions 2-154.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP56208.

Family & Domainsi

Sequence similaritiesi

Belongs to the globin family.PROSITE-ProRule annotation

Phylogenomic databases

HOVERGENiHBG107340.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P56208-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLSDDEWNH VLGIWAKVEP DLSAHGQEVI IRLFQLHPET QERFAKFKNL
60 70 80 90 100
TTIDALKSSE EVKKHGTTVL TALGRILKQK NNHEQELKPL AESHATKHKI
110 120 130 140 150
PVKYLEFICE IIVKVIAEKH PSDFGADSQA AMKKALELFR NDMASKYKEF

GFQG
Length:154
Mass (Da):17,522
Last modified:January 23, 2007 - v2
Checksum:i3D67EBD5FE1075E9
GO

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1LHSX-ray2.00A2-154[»]
1LHTX-ray2.00A2-154[»]
ProteinModelPortaliP56208.
SMRiP56208. Positions 2-154.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP56208.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG107340.

Miscellaneous databases

EvolutionaryTraceiP56208.

Family and domain databases

Gene3Di1.10.490.10. 1 hit.
InterProiIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin/Proto.
IPR002335. Myoglobin.
[Graphical view]
PANTHERiPTHR11442:SF5. PTHR11442:SF5. 1 hit.
PfamiPF00042. Globin. 1 hit.
[Graphical view]
PRINTSiPR00613. MYOGLOBIN.
SUPFAMiSSF46458. SSF46458. 1 hit.
PROSITEiPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structural studies on the loggerhead sea turtle (Caretta caretta) myoglobin."
    Petruzzelli R., Aureli G., Casale E., Nardini M., Rizzi M., Ascenzi P., Coletta M., de Sanctis G., Desideri A., Galtieri A., Bolognesi M.
    Biochem. Mol. Biol. Int. 31:19-24(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-154.
  2. "Reptile heme protein structure: X-ray crystallographic study of the aquo-met and cyano-met derivatives of the loggerhead sea turtle (Caretta caretta) myoglobin at 2.0-A resolution."
    Nardini M., Tarricone C., Rizzi M., Lania A., Desideri A., de Sanctis G., Coletta M., Petruzzelli R., Ascenzi P., Coda A., Bolognesi M.
    J. Mol. Biol. 247:459-465(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-154 IN COMPLEX WITH HEME.

Entry informationi

Entry nameiMYG_CARCR
AccessioniPrimary (citable) accession number: P56208
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: January 23, 2007
Last modified: January 20, 2016
This is version 76 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.