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P56185 (RNJ_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease J

Short name=RNase J
EC=3.1.-.-
Gene names
Ordered Locus Names:HP_1430
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length689 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Cofactor

Divalent metal cations By similarity.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. RNase J subfamily.

Ontologies

Keywords
   Cellular componentCytoplasm
   LigandMetal-binding
RNA-binding
   Molecular functionEndonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

endonuclease activity

Inferred from electronic annotation. Source: UniProtKB-KW

metal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 689689Ribonuclease J
PRO_0000215269

Sites

Metal binding2061Divalent metal cation 1 By similarity
Metal binding2081Divalent metal cation 1 By similarity
Metal binding2101Divalent metal cation 2 By similarity
Metal binding2111Divalent metal cation 2 By similarity
Metal binding2751Divalent metal cation 1 By similarity
Metal binding2971Divalent metal cation 1 By similarity
Metal binding2971Divalent metal cation 2 By similarity
Metal binding5331Divalent metal cation 2 By similarity

Sequences

Sequence LengthMass (Da)Tools
P56185 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 77791982943F5B80

FASTA68977,386
        10         20         30         40         50         60 
MTDNNQNNEN HENSSENSKA DEMRAGAFER FTNRKKRFRE NAQKNAEYSN HEASSHHKKE 

        70         80         90        100        110        120 
HRPNKKPNNH HKQKHAKTRN YAQEELDSNK VEGVTEILHV NERGTLGFHK ELKKGVEANN 

       130        140        150        160        170        180 
KIQVEHLNPH YKMNLNSKAS VKITPLGGLG EIGGNMMVIE TPKSAIVIDA GMSFPKEGLF 

       190        200        210        220        230        240 
GVDILIPDFS YLHQIKDKIA GIIITHAHED HIGATPYLFK ELQFPLYGTP LSLGLIGSKF 

       250        260        270        280        290        300 
DEHGLKKYRS YFKIVEKRCP ISVGEFIIEW IHITHSIIDS SALAIQTKAG TIIHTGDFKI 

       310        320        330        340        350        360 
DHTPVDNLPT DLYRLAHYGE KGVMLLLSDS TNSHKSGTTP SESTIAPAFD TLFKEAQGRV 

       370        380        390        400        410        420 
IMSTFSSNIH RVYQAIQYGI KYNRKIAVIG RSMEKNLDIA RELGYIHLPY QSFIEANEVA 

       430        440        450        460        470        480 
KYPDNEILIV TTGSQGETMS ALYRMATDEH RHISIKPNDL VIISAKAIPG NEASVSAVLN 

       490        500        510        520        530        540 
FLIKKEAKVA YQEFDNIHVS GHAAQEEQKL MLRLIKPKFF LPVHGEYNHV ARHKQTAISC 

       550        560        570        580        590        600 
GVPEKNIYLM EDGDQVEVGP AFIKKVGTIK SGKSYVDNQS NLSIDTSIVQ QREEVASAGV 

       610        620        630        640        650        660 
FVATIFVNKN KQALLESSQF SSLGLVGFKD EKPLIKEIQG GLEVLLKSSN AEILNNPKKL 

       670        680 
EDHTRNFIRK ALFKKFRKYP AIICHAHSF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD08469.1.
PIRF64698.
RefSeqNP_208221.1. NC_000915.1.
YP_006935351.1. NC_018939.1.

3D structure databases

ProteinModelPortalP56185.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-3218N.
IntActP56185. 13 interactions.
MINTMINT-177855.
STRING85962.HP1430.

Proteomic databases

PRIDEP56185.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD08469; AAD08469; HP_1430.
GeneID13870640.
899865.
KEGGheo:C694_07395.
hpy:HP1430.
PATRIC20594259. VBIHelPyl33062_1499.

Phylogenomic databases

eggNOGCOG0595.
KOK12574.
OMAYGPRLAM.
OrthoDBEOG6P5ZDC.
ProtClustDBCLSK872552.

Enzyme and pathway databases

BioCycHPY:HP1430-MONOMER.

Family and domain databases

Gene3D3.60.15.10. 1 hit.
InterProIPR001279. Beta-lactamas-like.
IPR011108. RMMBL.
IPR004613. RNase_J.
IPR001587. RNase_J_CS.
[Graphical view]
PANTHERPTHR11203:SF22. PTHR11203:SF22. 1 hit.
PfamPF00753. Lactamase_B. 1 hit.
PF07521. RMMBL. 1 hit.
[Graphical view]
PIRSFPIRSF004803. RnjA. 1 hit.
SMARTSM00849. Lactamase_B. 1 hit.
[Graphical view]
SUPFAMSSF56281. SSF56281. 1 hit.
TIGRFAMsTIGR00649. MG423. 1 hit.
PROSITEPS01292. UPF0036. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRNJ_HELPY
AccessionPrimary (citable) accession number: P56185
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names