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P56154

- PGK_HELPY

UniProt

P56154 - PGK_HELPY

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Protein

Phosphoglycerate kinase

Gene

pgk

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei45 – 451SubstrateBy similarity
Binding sitei125 – 1251SubstrateBy similarity
Binding sitei158 – 1581SubstrateBy similarity
Binding sitei209 – 2091ATPBy similarity
Binding sitei331 – 3311ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi357 – 3604ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP1345-MONOMER.
UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:pgk
Ordered Locus Names:HP_1345
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 402402Phosphoglycerate kinasePRO_0000145950Add
BLAST

Proteomic databases

PRIDEiP56154.

Interactioni

Protein-protein interaction databases

DIPiDIP-3617N.
IntActiP56154. 3 interactions.
MINTiMINT-174705.
STRINGi85962.HP1345.

Structurei

3D structure databases

ProteinModelPortaliP56154.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni29 – 313Substrate bindingBy similarity
Regioni69 – 724Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Phylogenomic databases

eggNOGiCOG0126.
KOiK00927.
OMAiDSICEND.
OrthoDBiEOG64N9Z0.

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P56154-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLAKMSFMQN VKNIQEVEVS HKRVLIRVDF NVPLDENLNI TDDTRIRESL
60 70 80 90 100
PTIQYCIDNK AKDIILVSHL GRPKGVEEKL SLKPFLKRLE RLLNHEVVFS
110 120 130 140 150
QNIVQLKQAL NENAPTRIFL LENIRFLRGE EENDENLAKD LASLCDVFVN
160 170 180 190 200
DAFGTSHRKH ASTYGTAKFA PIKVSGFLLK KEIDSFYQAF NHPLRPLLLI
210 220 230 240 250
VGGAKVSSKL TLLKNILDLI DKLIIAGAMS NTFLKALGYD VQDSSVEDAL
260 270 280 290 300
INDALELLQS AKEKKVKVYL PIDAVTTDDI LNPKHIKISP VQDIEPKHKI
310 320 330 340 350
ADIGPASLKL FSEVIESAPT ILWNGPLGVH EKQEFARGTT FLAHKIADTY
360 370 380 390 400
AFSLIGGGDT IDAINRAGEK DNMSFISTGG GASLELLEGK ILPCFEVLDK

RH
Length:402
Mass (Da):44,772
Last modified:November 1, 1997 - v1
Checksum:iD74B63DBAF4465D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08386.1.
PIRiA64688.
RefSeqiNP_208137.1. NC_000915.1.
YP_006935266.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD08386; AAD08386; HP_1345.
GeneIDi13870553.
900358.
KEGGiheo:C694_06940.
hpy:HP1345.
PATRICi20594075. VBIHelPyl33062_1408.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD08386.1 .
PIRi A64688.
RefSeqi NP_208137.1. NC_000915.1.
YP_006935266.1. NC_018939.1.

3D structure databases

ProteinModelPortali P56154.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-3617N.
IntActi P56154. 3 interactions.
MINTi MINT-174705.
STRINGi 85962.HP1345.

Proteomic databases

PRIDEi P56154.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD08386 ; AAD08386 ; HP_1345 .
GeneIDi 13870553.
900358.
KEGGi heo:C694_06940.
hpy:HP1345.
PATRICi 20594075. VBIHelPyl33062_1408.

Phylogenomic databases

eggNOGi COG0126.
KOi K00927.
OMAi DSICEND.
OrthoDBi EOG64N9Z0.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .
BioCyci HPY:HP1345-MONOMER.

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiPGK_HELPY
AccessioniPrimary (citable) accession number: P56154
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3