Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P56144

- TRUA_HELPY

UniProt

P56144 - TRUA_HELPY

Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

    Catalytic activityi

    tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei51 – 511NucleophileUniRule annotation
    Binding sitei107 – 1071SubstrateUniRule annotation

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: UniProtKB-HAMAP
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    tRNA processing

    Enzyme and pathway databases

    BioCyciHPY:HP0361-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
    Alternative name(s):
    tRNA pseudouridine(38-40) synthaseUniRule annotation
    tRNA pseudouridylate synthase IUniRule annotation
    tRNA-uridine isomerase IUniRule annotation
    Gene namesi
    Name:truAUniRule annotation
    Synonyms:hisT
    Ordered Locus Names:HP_0361
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 242242tRNA pseudouridine synthase APRO_0000057390Add
    BLAST

    Proteomic databases

    PRIDEiP56144.

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    IntActiP56144. 3 interactions.
    STRINGi85962.HP0361.

    Structurei

    3D structure databases

    ProteinModelPortaliP56144.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0101.
    KOiK06173.
    OMAiFNAFAYT.
    OrthoDBiEOG6Z9B4R.

    Family and domain databases

    Gene3Di3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPiMF_00171. TruA.
    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view]
    PANTHERiPTHR11142. PTHR11142. 1 hit.
    PfamiPF01416. PseudoU_synth_1. 2 hits.
    [Graphical view]
    PIRSFiPIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00071. hisT_truA. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P56144-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRCFKATIAY DGAYFLGYAK QPNKLGVQDK IEDALNALGI KSVVIAAGRT    50
    DKGVHANNQV LSFHAPKHWN AAKLFYYLAP KLAPHIVLKK LEEKNFHARF 100
    DAQKRAYRYL LTKNLKTPFL APYIACGDYG SLDALNTALK QFTGKHDFSM 150
    FKKEGGATTN PKRTIFNAFA YKTFIIGHEC VVFKIIGDAF LRSSVRLIIQ 200
    ACVQYSLEKI TLAEIQAQIH NLKATIRTPI MANGLYLHRV YY 242
    Length:242
    Mass (Da):27,312
    Last modified:November 1, 1997 - v1
    Checksum:i76C4093AC440B78D
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07429.1.
    PIRiA64565.
    RefSeqiNP_207159.1. NC_000915.1.
    YP_006934285.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD07429; AAD07429; HP_0361.
    GeneIDi13869546.
    900091.
    KEGGiheo:C694_01830.
    hpy:HP0361.
    PATRICi20591957. VBIHelPyl33062_0373.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07429.1 .
    PIRi A64565.
    RefSeqi NP_207159.1. NC_000915.1.
    YP_006934285.1. NC_018939.1.

    3D structure databases

    ProteinModelPortali P56144.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi P56144. 3 interactions.
    STRINGi 85962.HP0361.

    Proteomic databases

    PRIDEi P56144.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD07429 ; AAD07429 ; HP_0361 .
    GeneIDi 13869546.
    900091.
    KEGGi heo:C694_01830.
    hpy:HP0361.
    PATRICi 20591957. VBIHelPyl33062_0373.

    Phylogenomic databases

    eggNOGi COG0101.
    KOi K06173.
    OMAi FNAFAYT.
    OrthoDBi EOG6Z9B4R.

    Enzyme and pathway databases

    BioCyci HPY:HP0361-MONOMER.

    Family and domain databases

    Gene3Di 3.30.70.580. 1 hit.
    3.30.70.660. 1 hit.
    HAMAPi MF_00171. TruA.
    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR001406. PsdUridine_synth_TruA.
    IPR020097. PsdUridine_synth_TruA_a/b_dom.
    IPR020095. PsdUridine_synth_TruA_C.
    IPR020094. PsdUridine_synth_TruA_N.
    [Graphical view ]
    PANTHERi PTHR11142. PTHR11142. 1 hit.
    Pfami PF01416. PseudoU_synth_1. 2 hits.
    [Graphical view ]
    PIRSFi PIRSF001430. tRNA_psdUrid_synth. 1 hit.
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00071. hisT_truA. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiTRUA_HELPY
    AccessioniPrimary (citable) accession number: P56144
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3