Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P56144

- TRUA_HELPY

UniProt

P56144 - TRUA_HELPY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei51 – 511NucleophileUniRule annotation
Binding sitei107 – 1071SubstrateUniRule annotation

GO - Molecular functioni

  1. pseudouridine synthase activity Source: UniProtKB-HAMAP
  2. RNA binding Source: InterPro

GO - Biological processi

  1. tRNA pseudouridine synthesis Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

tRNA processing

Enzyme and pathway databases

BioCyciHPY:HP0361-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotation
Synonyms:hisT
Ordered Locus Names:HP_0361
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 242242tRNA pseudouridine synthase APRO_0000057390Add
BLAST

Proteomic databases

PRIDEiP56144.

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

IntActiP56144. 3 interactions.
STRINGi85962.HP0361.

Structurei

3D structure databases

ProteinModelPortaliP56144.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0101.
KOiK06173.
OMAiFNAFAYT.
OrthoDBiEOG6Z9B4R.

Family and domain databases

Gene3Di3.30.70.580. 1 hit.
3.30.70.660. 1 hit.
HAMAPiMF_00171. TruA.
InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view]
PANTHERiPTHR11142. PTHR11142. 1 hit.
PfamiPF01416. PseudoU_synth_1. 2 hits.
[Graphical view]
PIRSFiPIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00071. hisT_truA. 1 hit.

Sequencei

Sequence statusi: Complete.

P56144-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRCFKATIAY DGAYFLGYAK QPNKLGVQDK IEDALNALGI KSVVIAAGRT
60 70 80 90 100
DKGVHANNQV LSFHAPKHWN AAKLFYYLAP KLAPHIVLKK LEEKNFHARF
110 120 130 140 150
DAQKRAYRYL LTKNLKTPFL APYIACGDYG SLDALNTALK QFTGKHDFSM
160 170 180 190 200
FKKEGGATTN PKRTIFNAFA YKTFIIGHEC VVFKIIGDAF LRSSVRLIIQ
210 220 230 240
ACVQYSLEKI TLAEIQAQIH NLKATIRTPI MANGLYLHRV YY
Length:242
Mass (Da):27,312
Last modified:November 1, 1997 - v1
Checksum:i76C4093AC440B78D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07429.1.
PIRiA64565.
RefSeqiNP_207159.1. NC_000915.1.
YP_006934285.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07429; AAD07429; HP_0361.
GeneIDi13869546.
900091.
KEGGiheo:C694_01830.
hpy:HP0361.
PATRICi20591957. VBIHelPyl33062_0373.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07429.1 .
PIRi A64565.
RefSeqi NP_207159.1. NC_000915.1.
YP_006934285.1. NC_018939.1.

3D structure databases

ProteinModelPortali P56144.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P56144. 3 interactions.
STRINGi 85962.HP0361.

Proteomic databases

PRIDEi P56144.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD07429 ; AAD07429 ; HP_0361 .
GeneIDi 13869546.
900091.
KEGGi heo:C694_01830.
hpy:HP0361.
PATRICi 20591957. VBIHelPyl33062_0373.

Phylogenomic databases

eggNOGi COG0101.
KOi K06173.
OMAi FNAFAYT.
OrthoDBi EOG6Z9B4R.

Enzyme and pathway databases

BioCyci HPY:HP0361-MONOMER.

Family and domain databases

Gene3Di 3.30.70.580. 1 hit.
3.30.70.660. 1 hit.
HAMAPi MF_00171. TruA.
InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR001406. PsdUridine_synth_TruA.
IPR020097. PsdUridine_synth_TruA_a/b_dom.
IPR020095. PsdUridine_synth_TruA_C.
IPR020094. PsdUridine_synth_TruA_N.
[Graphical view ]
PANTHERi PTHR11142. PTHR11142. 1 hit.
Pfami PF01416. PseudoU_synth_1. 2 hits.
[Graphical view ]
PIRSFi PIRSF001430. tRNA_psdUrid_synth. 1 hit.
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00071. hisT_truA. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiTRUA_HELPY
AccessioniPrimary (citable) accession number: P56144
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 1, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3