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Protein

RNA polymerase sigma-54 factor

Gene

rpoN

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi301 – 320H-T-H motifBy similarityAdd BLAST20

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Nucleotidyltransferase, Sigma factor, Transferase
Biological processTranscription, Transcription regulation

Enzyme and pathway databases

BioCyciHPY:HP0714-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase sigma-54 factor
Gene namesi
Name:rpoN
Ordered Locus Names:HP_0714
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002055311 – 414RNA polymerase sigma-54 factorAdd BLAST414

Proteomic databases

PaxDbiP56143.

Interactioni

Protein-protein interaction databases

DIPiDIP-3064N.
IntActiP56143. 11 interactors.
MINTiMINT-168088.
STRINGi85962.HP0714.

Structurei

3D structure databases

ProteinModelPortaliP56143.
SMRiP56143.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi387 – 395RPON box9

Sequence similaritiesi

Belongs to the sigma-54 factor family.Curated

Phylogenomic databases

eggNOGiENOG4105DTW. Bacteria.
COG1508. LUCA.
KOiK03092.
OMAiVTTQKFM.

Family and domain databases

Gene3Di1.10.10.10. 1 hit.
InterProiView protein in InterPro
IPR000394. RNA_pol_sigma_54.
IPR007046. RNA_pol_sigma_54_core-bd.
IPR007634. RNA_pol_sigma_54_DNA-bd.
IPR036388. WH-like_DNA-bd_sf.
PANTHERiPTHR32248. PTHR32248. 1 hit.
PfamiView protein in Pfam
PF00309. Sigma54_AID. 1 hit.
PF04963. Sigma54_CBD. 1 hit.
PF04552. Sigma54_DBD. 1 hit.
PIRSFiPIRSF000774. RpoN. 1 hit.
PRINTSiPR00045. SIGMA54FCT.
TIGRFAMsiTIGR02395. rpoN_sigma. 1 hit.
PROSITEiView protein in PROSITE
PS00717. SIGMA54_1. 1 hit.
PS00718. SIGMA54_2. 1 hit.
PS50044. SIGMA54_3. 1 hit.

Sequencei

Sequence statusi: Complete.

P56143-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAILRANLSP KNKLNATLKG WLPILQSELE DLEEVLKQNA LDNPLIKIEN
60 70 80 90 100
KRIKNFSDRF SAKKSSDHLE NFATASKSLF ETLEAQIIPP LFPTETSQKI
110 120 130 140 150
AMDIISGLNN EGYFEENIEE RARILGVESE VYEKVRKRFS YLNPAGIGAK
160 170 180 190 200
DVKESFLFQL ESRELDDNEL YEETRKIILN LEKHHEFSKD FYYEKALKIL
210 220 230 240 250
KSFKNPPAIE FLEKEIEVIP ELFIVEVDNG IIVRLNDESY PTISLEENRF
260 270 280 290 300
KDSGYLKEKL KEAKDLIDAL NLRKATIYKI GLMLLEYQYD FFKGKELRPL
310 320 330 340 350
KLLDLANEFN HSVSTISRAI SNKYLACERG VFPIKHFFSI ALDNSETSNA
360 370 380 390 400
VIKDYLLELI KNEDKKEPLS DAKILELIEE KFHLKMVRRT ITKYRQLLNI
410
ASSSERKRLY LMRA
Length:414
Mass (Da):48,173
Last modified:November 1, 1997 - v1
Checksum:iC7781CE32B5B04FE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07764.1.
PIRiB64609.
RefSeqiNP_207508.1. NC_000915.1.
WP_000996418.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07764; AAD07764; HP_0714.
GeneIDi900248.
KEGGiheo:C694_03675.
hpy:HP0714.
PATRICifig|85962.47.peg.763.

Similar proteinsi

Entry informationi

Entry nameiRP54_HELPY
AccessioniPrimary (citable) accession number: P56143
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 25, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families