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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP0319-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:HP_0319
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
Proteomesi
  • UP000000429 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001515651 – 541Arginine--tRNA ligaseAdd BLAST541

Proteomic databases

PaxDbiP56128.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

DIPiDIP-3643N.
IntActiP56128. 2 interactors.
MINTiMINT-169291.
STRINGi85962.HP0319.

Structurei

3D structure databases

ProteinModelPortaliP56128.
SMRiP56128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi119 – 129"HIGH" regionAdd BLAST11

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105C75. Bacteria.
COG0018. LUCA.
KOiK01887.
OMAiNKPLHLG.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiView protein in PROSITE
PS00178. AA_TRNA_LIGASE_I. 1 hit.

Sequencei

Sequence statusi: Complete.

P56128-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHTLIKGILE EILEEEVIVE YPKDREHGHY ATPIAFNLAK VFKKSPLAIA
60 70 80 90 100
EELALKISTH EKTQGLFDSV VACKGYINFT LSLDFLERFT QKALELKEKF
110 120 130 140 150
GSQVKSERSQ KIFLEFVSAN PTGPLHIGHA RGAVFGDSLA KIARFLGHEV
160 170 180 190 200
LCEYYVNDMG SQIRLLGLSV WLAYREHVLK ESVTYPEVFY KGEYIIEIAK
210 220 230 240 250
KANNDLEPSL LKENEETIIE VLSGYARDLM LLEIKDNLDA LGIHFDSYAS
260 270 280 290 300
EKEVFKHKDA VFEQLEKANA LYEKDSKIWL KSSLYQDESD RVLIKEDKSY
310 320 330 340 350
TYLAGDIVYH DEKFKQDYTK YINIWGADHH GYIARVKASL EFLGYDSNKL
360 370 380 390 400
EVLLAQMVRL LKDNEPYKMS KRAGNFILIK DVVDDVGKDA LRFIFLSKRL
410 420 430 440 450
DTHLEFDVNT LKKQDSSNPI YYIHYANSRI HTMLEKSPFS KEEVLQTPLT
460 470 480 490 500
NLNAEEKYLL FSALSLPKAI ESSFEEYGLQ KMCEYAKTLA SEFHRFYNAG
510 520 530 540
KILDTPKAKE LLKICLIVSL SLSNAFKLLG IEIKTKISAR D
Length:541
Mass (Da):62,077
Last modified:November 1, 1997 - v1
Checksum:iDAB18669FD03A866
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07388.1.
PIRiG64559.
RefSeqiNP_207117.1. NC_000915.1.
WP_000557124.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07388; AAD07388; HP_0319.
GeneIDi900101.
KEGGiheo:C694_01615.
hpy:HP0319.
PATRICifig|85962.47.peg.341.

Similar proteinsi

Entry informationi

Entry nameiSYR_HELPY
AccessioniPrimary (citable) accession number: P56128
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 22, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families