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P56128

- SYR_HELPY

UniProt

P56128 - SYR_HELPY

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP0319-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:HP_0319
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 541541Arginine--tRNA ligasePRO_0000151565Add
BLAST

Proteomic databases

PRIDEiP56128.

Interactioni

Subunit structurei

Monomer.By similarity

Protein-protein interaction databases

DIPiDIP-3643N.
IntActiP56128. 2 interactions.
MINTiMINT-169291.
STRINGi85962.HP0319.

Structurei

3D structure databases

ProteinModelPortaliP56128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi119 – 12911"HIGH" regionAdd
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
KOiK01887.
OMAiIRNTIND.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P56128-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHTLIKGILE EILEEEVIVE YPKDREHGHY ATPIAFNLAK VFKKSPLAIA
60 70 80 90 100
EELALKISTH EKTQGLFDSV VACKGYINFT LSLDFLERFT QKALELKEKF
110 120 130 140 150
GSQVKSERSQ KIFLEFVSAN PTGPLHIGHA RGAVFGDSLA KIARFLGHEV
160 170 180 190 200
LCEYYVNDMG SQIRLLGLSV WLAYREHVLK ESVTYPEVFY KGEYIIEIAK
210 220 230 240 250
KANNDLEPSL LKENEETIIE VLSGYARDLM LLEIKDNLDA LGIHFDSYAS
260 270 280 290 300
EKEVFKHKDA VFEQLEKANA LYEKDSKIWL KSSLYQDESD RVLIKEDKSY
310 320 330 340 350
TYLAGDIVYH DEKFKQDYTK YINIWGADHH GYIARVKASL EFLGYDSNKL
360 370 380 390 400
EVLLAQMVRL LKDNEPYKMS KRAGNFILIK DVVDDVGKDA LRFIFLSKRL
410 420 430 440 450
DTHLEFDVNT LKKQDSSNPI YYIHYANSRI HTMLEKSPFS KEEVLQTPLT
460 470 480 490 500
NLNAEEKYLL FSALSLPKAI ESSFEEYGLQ KMCEYAKTLA SEFHRFYNAG
510 520 530 540
KILDTPKAKE LLKICLIVSL SLSNAFKLLG IEIKTKISAR D
Length:541
Mass (Da):62,077
Last modified:November 1, 1997 - v1
Checksum:iDAB18669FD03A866
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07388.1.
PIRiG64559.
RefSeqiNP_207117.1. NC_000915.1.
YP_006934247.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07388; AAD07388; HP_0319.
GeneIDi13869505.
900101.
KEGGiheo:C694_01615.
hpy:HP0319.
PATRICi20591869. VBIHelPyl33062_0332.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07388.1 .
PIRi G64559.
RefSeqi NP_207117.1. NC_000915.1.
YP_006934247.1. NC_018939.1.

3D structure databases

ProteinModelPortali P56128.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-3643N.
IntActi P56128. 2 interactions.
MINTi MINT-169291.
STRINGi 85962.HP0319.

Proteomic databases

PRIDEi P56128.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD07388 ; AAD07388 ; HP_0319 .
GeneIDi 13869505.
900101.
KEGGi heo:C694_01615.
hpy:HP0319.
PATRICi 20591869. VBIHelPyl33062_0332.

Phylogenomic databases

eggNOGi COG0018.
KOi K01887.
OMAi IRNTIND.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci HPY:HP0319-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiSYR_HELPY
AccessioniPrimary (citable) accession number: P56128
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3