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P56119 (AROE_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 96. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Shikimate dehydrogenase

EC=1.1.1.25
Gene names
Name:aroE
Ordered Locus Names:HP_1249
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) [Reference proteome] [HAMAP]
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 263263Shikimate dehydrogenase HAMAP-Rule MF_00222
PRO_0000136007

Regions

Nucleotide binding125 – 1295NADP By similarity

Sites

Active site691Proton acceptor Potential

Secondary structure

.................................................. 263
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
P56119 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: A34E5BD3E54C4937

FASTA26329,273
        10         20         30         40         50         60 
MKLKSFGVFG NPIKHSKSPL IHNACFLTFQ KELRFLGHYH PILLPLESHI KSEFLHLGLS 

        70         80         90        100        110        120 
GANVTLPFKE RAFQVCDKIK GIALECGAVN TLVLENDELV GYNTDALGFY LSLKQKNYQN 

       130        140        150        160        170        180 
ALILGAGGSA KALACELKKQ GLQVSVLNRS SRGLDFFQRL GCDCFMEPPK SAFDLIINAT 

       190        200        210        220        230        240 
SASLHNELPL NKEVLKGYFK EGKLAYDLAY GFLTPFLSLA KELKTPFQDG KDMLIYQAAL 

       250        260 
SFEKFSASQI PYSKAFEVMR SVF 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE000511 Genomic DNA. Translation: AAD08294.1.
PIRA64676.
RefSeqNP_208041.1. NC_000915.1.
YP_006935169.1. NC_018939.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3PHGX-ray1.57A/B1-263[»]
3PHHX-ray1.42A1-263[»]
3PHIX-ray2.04A/B1-263[»]
3PHJX-ray2.30A/B1-263[»]
4FOOX-ray2.55A/B1-263[»]
4FOSX-ray1.72A1-263[»]
4FPXX-ray2.40A/B1-263[»]
4FQ8X-ray2.07A/B1-263[»]
4FR5X-ray2.20A/B1-263[»]
4FSHX-ray2.85A/B1-263[»]
ProteinModelPortalP56119.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP56119. 1 interaction.
STRING85962.HP1249.

PTM databases

PhosSiteP11041007.

Proteomic databases

PRIDEP56119.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAD08294; AAD08294; HP_1249.
GeneID898819.
KEGGheo:C694_06455.
hpy:HP1249.
PATRIC20593875. VBIHelPyl33062_1308.

Phylogenomic databases

eggNOGCOG0169.
KOK00014.
OMAASMDSIP.
OrthoDBEOG64R67G.

Enzyme and pathway databases

BioCycHPY:HP1249-MONOMER.
UniPathwayUPA00053; UER00087.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_00222. Shikimate_DH_AroE.
InterProIPR016040. NAD(P)-bd_dom.
IPR011342. Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view]
PfamPF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00507. aroE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROE_HELPY
AccessionPrimary (citable) accession number: P56119
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 9, 2014
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

PATHWAY comments

Index of metabolic and biosynthesis pathways

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names