Reviewed, UniProtKB/Swiss-Prot P56113 (Y169_HELPY)

Names and origin

Protein names

Recommended name:
    Uncharacterized protease HP_0169
    EC=3.4.-.-

Gene names

Ordered Locus Names:

HP_0169

Organism

Helicobacter pylori (Campylobacter pylori) [Complete proteome] [HAMAP]

Taxonomic identifier

210 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	422 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Sequence similarities

Belongs to the peptidase U32 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Hydrolase Protease
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro
Molecular function	peptidase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 58	58	Potential
	Chain	59 – 422	364	Uncharacterized protease HP_0169		PRO_0000028526

Sequences

	Sequence		Length	Mass (Da)
	P56113-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: C2CDADA9480A77A1	FASTA	422	47,275
	10 20 30 40 50 60 MNQVELLSPA GNLKKLKIAL NYGADAVYGG VSHFSLRNRA GKEFTLETFK EGIDYAHALN 70 80 90 100 110 120 KKVYATINGF PFNSQLKLLE EHIDKMAELE PDAFIIAAPG VVKLALKIAP HIPIHLSTQA 130 140 150 160 170 180 NVLNLLDAQV FYDLGVKRIV CARELSLNDA IEIKKALPNL ELEIFVHGSM CFAFSGRCLI 190 200 210 220 230 240 SALQKGRVPN RGSCANDCRF DYEYYVKNPD NGVMMRLVEE EGVGTHIFNA KDLNLSGHIA 250 260 270 280 290 300 EILSSNAISA LKIEGRTKSS YYAAQTTRIY RLAVDDFYHN TLKPSFYASE LNTLKNRGFT 310 320 330 340 350 360 DGYLMRRPFE RLDTQNHQTA ISEGDFQVNG EITEDGRFFA CKFTTTTNTA YEIIAPKNAA 370 380 390 400 410 420 ITPIVNEIGK IYTFEKRSYL VLYKILLENN TELETIHSGN VNLVRLPAPL PAFSFLRTQV RV

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed: 9252185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE000511 Genomic DNA. Translation: AAD07235.1.
PIR	A64541.
RefSeq	NP_206968.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	899006.
GenomeReviews	Gene locus HP_0169 in contig AE000511_GR.
KEGG	hpy:HP0169.
NMPDR	fig|85962.1.peg.166.
TIGR	HP_0169.
Phylogenomic databases
HOGENOM	P56113.
OMA	DLRAVEH
Family and domain databases
InterPro	IPR001539. Peptidase_U32. [Graphical view]
Pfam	PF01136. Peptidase_U32. 1 hit. [Graphical view]
PROSITE	PS01276. PEPTIDASE_U32. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y169_HELPY

Accession

Primary (citable) accession number: P56113

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 24, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)