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P56111 (EDD_HELPY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphogluconate dehydratase
EC=4.2.1.12
Alternative name(s):
6-phosphogluconate dehydratase
Gene names
Name:edd
Ordered Locus Names:HP_1100
OrganismHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifier85962 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length608 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H2O.

Pathway

Carbohydrate metabolism; Entner-Doudoroff pathway.

Sequence similarities

Belongs to the IlvD/Edd family.

Ontologies

Keywords
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processEntner-Doudoroff pathway

Inferred from electronic annotation. Source: InterPro

   Molecular functionphosphogluconate dehydratase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 608608Phosphogluconate dehydratase
PRO_0000103555

Sequences

Sequence LengthMass (Da)Tools
P56111 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 47EF7E62E3371F59

FASTA60866,655
        10         20         30         40         50         60 
MPKHSLEQIK EKITERSKKT RELYLENIFN PKNQPKIESL GCANIAHVTA SMPEHLKMPL 

        70         80         90        100        110        120 
GSHKRKHFAI ITAYNDMLSA HQPFKNYPDL IKKELQEHNA YASVASGVPA MCDGITQGYD 

       130        140        150        160        170        180 
GMELSLFSRD VIALSTAVGL SHNVFDGAFF LGVCDKIVPG LLIGALSFGN LASVFVPSGP 

       190        200        210        220        230        240 
MVSGIENYKK AKARQDFAMG KINREELLKV EMQSYHDVGT CTFYGTANSN QMMMEFMGLH 

       250        260        270        280        290        300 
VANSSFINPN NPLRKVLVEE SAKRLASGKV LPLAKLIDEK SILNALIGLM ATGGSTNHTL 

       310        320        330        340        350        360 
HLIAIARSCG VILNWDDFDA VSNLIPLLAK VYPNGSADVN AFEACGGLVF VIKELLKEGL 

       370        380        390        400        410        420 
LFEDTHTIMD TETQKGMQNY TKTPFLENNQ LVYKDAINHS LNTDILRPVS DPFAANGGLK 

       430        440        450        460        470        480 
ILKGNLGRAV IKISAIKDEH RKVKARAIVF KTQSEFLERF KNKELERDFV AVLPFQGPKS 

       490        500        510        520        530        540 
NGMPELHKLT TNLGALQDMG YKVALVTDGR MSGASGKVPS AIHLSPEGAL NGAIIKIKDG 

       550        560        570        580        590        600 
DLIELDAPNN ALNVLEKDFE KRGINPLFLE TLENLEKPSF GLGRELFTSL RLNVNTAEEG 


GMSFGIKV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE000511 Genomic DNA. Translation: AAD08143.1.
PIRD64657.
RefSeqNP_207891.1. NC_000915.1.

3D structure databases

ProteinModelPortalP56111.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID899636.
GenomeReviewsGene locus HP_1100 in contig AE000511_GR.
KEGGhpy:HP1100.
NMPDRfig|85962.1.peg.1087.
PATRIC20593539. VBIHelPyl33062_1149.
TIGRHP_1100.

Phylogenomic databases

HOGENOMHBG671001.
OMAKDAINHS.
ProtClustDBPRK09054.

Family and domain databases

InterProIPR004786. 6-phosphgluc_deHydtase.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR000581. DiOHA_6PGluconate_deHydtase.
IPR020558. DiOHA_6PGluconate_deHydtase_CS.
[Graphical view]
KOK01690.
PANTHERPTHR21000. ILVD_EDD_family. 1 hit.
PfamPF00920. ILVD_EDD. 1 hit.
[Graphical view]
SUPFAMSSF52016. Aconitase/3IPM_dehydase_swvl. 1 hit.
TIGRFAMsTIGR01196. Edd. 1 hit.
PROSITEPS00886. ILVD_EDD_1. 1 hit.
PS00887. ILVD_EDD_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameEDD_HELPY
AccessionPrimary (citable) accession number: P56111
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Helicobacter pylori

Helicobacter pylori (strain 26695): entries and gene names

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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