Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P56103

- KGUA_HELPY

UniProt

P56103 - KGUA_HELPY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Guanylate kinase

Gene

gmk

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.By similarity

Catalytic activityi

ATP + GMP = ADP + GDP.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi12 – 198ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. guanylate kinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. purine nucleotide metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciHPY:HP0321-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinase (EC:2.7.4.8)
Alternative name(s):
GMP kinase
Gene namesi
Name:gmk
Ordered Locus Names:HP_0321
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 206206Guanylate kinasePRO_0000170547Add
BLAST

Proteomic databases

PRIDEiP56103.

Interactioni

Protein-protein interaction databases

DIPiDIP-3426N.
IntActiP56103. 3 interactions.
MINTiMINT-185893.
STRINGi85962.HP0321.

Structurei

3D structure databases

ProteinModelPortaliP56103.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 183179Guanylate kinase-likeAdd
BLAST

Sequence similaritiesi

Belongs to the guanylate kinase family.Curated
Contains 1 guanylate kinase-like domain.Curated

Phylogenomic databases

eggNOGiCOG0194.
KOiK00942.
OMAiDAVFSIS.
OrthoDBiEOG6CP410.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
HAMAPiMF_00328. Guanylate_kinase.
InterProiIPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00625. Guanylate_kin. 1 hit.
[Graphical view]
SMARTiSM00072. GuKc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR03263. guanyl_kin. 1 hit.
PROSITEiPS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P56103-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MHNDFNLLIL SGPSGAGKST LTKYLQEKIP KTHFSLSTTT RKPREGEVDG
60 70 80 90 100
LHYNFVSEEE FKQGIEKGQF LEWAIVHNHY YGTSKIPVEK ALKEGKIVIF
110 120 130 140 150
DIDVQGHEIL KKHYPNACSV FISTKNQEIL KERLLLRGTD SKETIEKRLI
160 170 180 190 200
NAYKEMQCLE SFDYLIINED LEKSKEIILS IAKTLVHRLK AFNFEKICKA

WKNETL
Length:206
Mass (Da):23,830
Last modified:November 1, 1997 - v1
Checksum:iAED9253D02C36A13
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07389.1.
PIRiA64560.
RefSeqiNP_207119.1. NC_000915.1.
YP_006934249.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07389; AAD07389; HP_0321.
GeneIDi13869507.
900200.
KEGGiheo:C694_01625.
hpy:HP0321.
PATRICi20591873. VBIHelPyl33062_0334.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000511 Genomic DNA. Translation: AAD07389.1 .
PIRi A64560.
RefSeqi NP_207119.1. NC_000915.1.
YP_006934249.1. NC_018939.1.

3D structure databases

ProteinModelPortali P56103.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-3426N.
IntActi P56103. 3 interactions.
MINTi MINT-185893.
STRINGi 85962.HP0321.

Proteomic databases

PRIDEi P56103.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD07389 ; AAD07389 ; HP_0321 .
GeneIDi 13869507.
900200.
KEGGi heo:C694_01625.
hpy:HP0321.
PATRICi 20591873. VBIHelPyl33062_0334.

Phylogenomic databases

eggNOGi COG0194.
KOi K00942.
OMAi DAVFSIS.
OrthoDBi EOG6CP410.

Enzyme and pathway databases

BioCyci HPY:HP0321-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 2 hits.
HAMAPi MF_00328. Guanylate_kinase.
InterProi IPR008145. GK/Ca_channel_bsu.
IPR008144. Guanylate_kin-like.
IPR017665. Guanylate_kinase.
IPR020590. Guanylate_kinase_CS.
IPR027417. P-loop_NTPase.
[Graphical view ]
Pfami PF00625. Guanylate_kin. 1 hit.
[Graphical view ]
SMARTi SM00072. GuKc. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 1 hit.
TIGRFAMsi TIGR03263. guanyl_kin. 1 hit.
PROSITEi PS00856. GUANYLATE_KINASE_1. 1 hit.
PS50052. GUANYLATE_KINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiKGUA_HELPY
AccessioniPrimary (citable) accession number: P56103
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3