P56082 (ATPG_HELPY) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
ATP synthase gamma chain

Alternative name(s):
ATP synthase F1 sector gamma subunit
F-ATPase gamma subunit

Gene names

Name:	atpG
Ordered Locus Names:	HP_1133

Organism

Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)

Taxonomic identifier

85962 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Epsilonproteobacteria › Campylobacterales › Helicobacteraceae › Helicobacter

Protein attributes

Sequence length	301 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF0 complex. HAMAP MF_00815
Subunit structure	F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a, b and c.
Subcellular location	Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00815.
Sequence similarities	Belongs to the ATPase gamma chain family.

Ontologies

Keywords
Biological process	ATP synthesis Hydrogen ion transport Ion transport Transport
Cellular component	CF(1) Cell inner membrane Cell membrane Membrane
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	ATP synthesis coupled proton transport Inferred from electronic annotation. Source: InterPro
Cellular component	plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proton-transporting ATP synthase complex, catalytic core F(1) Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	hydrogen ion transporting ATP synthase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro proton-transporting ATPase activity, rotational mechanism Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 301	301	ATP synthase gamma chain HAMAP MF_00815		PRO_0000073295

Sequences

	Sequence		Length	Mass (Da)
	P56082 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: A6F49A2E50376F85	FASTA	301	34,128
	10 20 30 40 50 60 MANLRDIRKK IGSVKNTQKI THAMKLVSTS KLRKAEEVAR NSRAYALKLD AVFDDVLSKM 70 80 90 100 110 120 KNQGIEDIQS KYFRELERLE IKKVDIIFIT ADKGLCGGFN TNTIKKVLAC TNEYKEKDIK 130 140 150 160 170 180 VRLRGIGKKG NEYFSFNGIE VLDKINNLSS MPNYERVQEF MKKVVEDYLS GKTDKVIIIH 190 200 210 220 230 240 NGFKNMITQE IRVKTILPIG YKIIHQNPQP SETQETITSE PSGSEDEILD SLAEKYVEYS 250 260 270 280 290 300 LYYALIDSLA AEHSARMQAM DTATNNAKDL VKTLTISYNK ARQEAITTEL VEINAGVEAL K

References

[1]

"The complete genome sequence of the gastric pathogen Helicobacter pylori." Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J. , Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C. Nature 388:539-547(1997) [PubMed: 9252185] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 700392 / 26695.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE000511 Genomic DNA. Translation: AAD08175.1.
PIR	E64661.
RefSeq	NP_207924.1. NC_000915.1.
3D structure databases
ProteinModelPortal	P56082.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-3116N.
MINT	MINT-159836.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	899670.
GenomeReviews	Gene locus HP_1133 in contig AE000511_GR.
KEGG	hpy:HP1133.
NMPDR	fig|85962.1.peg.1120.
PATRIC	20593611. VBIHelPyl33062_1185.
TIGR	HP_1133.
Phylogenomic databases
HOGENOM	HBG586593.
OMA	MDTATNN.
ProtClustDB	PRK05621.
Family and domain databases
HAMAP	MF_00815. ATP_synth_gamma_bact. [Tree]
InterPro	IPR000131. ATPase_F1-cplx_gsu. IPR023633. ATPase_F1_gsu_dom. [Graphical view]
KO	K02115.
PANTHER	PTHR11693. ATPase_F1_gamma. 1 hit.
Pfam	PF00231. ATP-synt. 1 hit. [Graphical view]
PRINTS	PR00126. ATPASEGAMMA.
SUPFAM	SSF52943. ATPase_gamma. 1 hit.
TIGRFAMs	TIGR01146. ATPsyn_F1gamma. 1 hit.
PROSITE	PS00153. ATPASE_GAMMA. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ATPG_HELPY

Accession

Primary (citable) accession number: P56082

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	January 25, 2012
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program