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P56080

- Y117_HELPY

UniProt

P56080 - Y117_HELPY

Protein

UPF0026 protein HP_0117

Gene

HP_0117

Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine Potential.Curated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi33 – 331Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis
    Metal bindingi37 – 371Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis
    Metal bindingi40 – 401Iron-sulfur (4Fe-4S-S-AdoMet)Sequence Analysis

    GO - Molecular functioni

    1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
    2. catalytic activity Source: InterPro
    3. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

    Enzyme and pathway databases

    BioCyciHPY:HP0117-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UPF0026 protein HP_0117
    Gene namesi
    Ordered Locus Names:HP_0117
    OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
    Taxonomic identifieri85962 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
    ProteomesiUP000000429: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 308308UPF0026 protein HP_0117PRO_0000217864Add
    BLAST

    Proteomic databases

    PRIDEiP56080.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-3297N.
    IntActiP56080. 2 interactions.
    MINTiMINT-175797.
    STRINGi85962.HP0117.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UPF0026 family.Curated

    Phylogenomic databases

    eggNOGiCOG0731.
    OMAiISCGIDE.
    OrthoDBiEOG6TTVP9.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR007197. rSAM.
    [Graphical view]
    PfamiPF04055. Radical_SAM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P56080-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAKENPPIVF GPVLSRRFGK SLGVDLSPSK KQCNYNCIYC ELGKAKPIER    50
    MEEVIKVETL INAIQNALNN LTTPIDVLTI TANGEPTLYP HLLELIQSIK 100
    PFLKGVKTLI LSNGSLFYEP KVQQALKEFD IVKFSLDAID LKAFERVDKP 150
    YSKDINKILE GILRFSQIYQ GQLVAEVLLI KGVNDSANNL KLIAAFLKQI 200
    NIARVDLSTI DRPSSFKAPK LSEDELLKCS LFFEGLCVSL PKRSITQAKK 250
    LISCGIDELL ALISRRPLSA EEAPLILDSN AFKHLETLLN HKQITIKKVG 300
    SLEFYCAF 308
    Length:308
    Mass (Da):34,405
    Last modified:November 1, 1997 - v1
    Checksum:iBBAA863283FBDF4B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07185.1.
    PIRiE64534.
    RefSeqiNP_206917.1. NC_000915.1.
    YP_006934040.1. NC_018939.1.

    Genome annotation databases

    EnsemblBacteriaiAAD07185; AAD07185; HP_0117.
    GeneIDi13869296.
    900364.
    KEGGiheo:C694_00580.
    hpy:HP0117.
    PATRICi20591449. VBIHelPyl33062_0124.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE000511 Genomic DNA. Translation: AAD07185.1 .
    PIRi E64534.
    RefSeqi NP_206917.1. NC_000915.1.
    YP_006934040.1. NC_018939.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-3297N.
    IntActi P56080. 2 interactions.
    MINTi MINT-175797.
    STRINGi 85962.HP0117.

    Proteomic databases

    PRIDEi P56080.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAD07185 ; AAD07185 ; HP_0117 .
    GeneIDi 13869296.
    900364.
    KEGGi heo:C694_00580.
    hpy:HP0117.
    PATRICi 20591449. VBIHelPyl33062_0124.

    Phylogenomic databases

    eggNOGi COG0731.
    OMAi ISCGIDE.
    OrthoDBi EOG6TTVP9.

    Enzyme and pathway databases

    BioCyci HPY:HP0117-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR007197. rSAM.
    [Graphical view ]
    Pfami PF04055. Radical_SAM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 700392 / 26695.

    Entry informationi

    Entry nameiY117_HELPY
    AccessioniPrimary (citable) accession number: P56080
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Helicobacter pylori
      Helicobacter pylori (strain 26695): entries and gene names
    2. SIMILARITY comments
      Index of protein domains and families
    3. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries

    External Data

    Dasty 3