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P56080

- Y117_HELPY

UniProt

P56080 - Y117_HELPY

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Protein

UPF0026 protein HP_0117

Gene
HP_0117
Organism
Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine Reviewed prediction.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi33 – 331Iron-sulfur (4Fe-4S-S-AdoMet) Reviewed prediction
Metal bindingi37 – 371Iron-sulfur (4Fe-4S-S-AdoMet) Reviewed prediction
Metal bindingi40 – 401Iron-sulfur (4Fe-4S-S-AdoMet) Reviewed prediction

GO - Molecular functioni

  1. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  2. catalytic activity Source: InterPro
  3. metal ion binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

4Fe-4S, Iron, Iron-sulfur, Metal-binding, S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciHPY:HP0117-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0026 protein HP_0117
Gene namesi
Ordered Locus Names:HP_0117
OrganismiHelicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori)
Taxonomic identifieri85962 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesHelicobacteraceaeHelicobacter
ProteomesiUP000000429: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 308308UPF0026 protein HP_0117PRO_0000217864Add
BLAST

Proteomic databases

PRIDEiP56080.

Interactioni

Protein-protein interaction databases

DIPiDIP-3297N.
IntActiP56080. 2 interactions.
MINTiMINT-175797.
STRINGi85962.HP0117.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0026 family.

Phylogenomic databases

eggNOGiCOG0731.
OMAiISCGIDE.
OrthoDBiEOG6TTVP9.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
InterProiIPR013785. Aldolase_TIM.
IPR007197. rSAM.
[Graphical view]
PfamiPF04055. Radical_SAM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P56080-1 [UniParc]FASTAAdd to Basket

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MAKENPPIVF GPVLSRRFGK SLGVDLSPSK KQCNYNCIYC ELGKAKPIER    50
MEEVIKVETL INAIQNALNN LTTPIDVLTI TANGEPTLYP HLLELIQSIK 100
PFLKGVKTLI LSNGSLFYEP KVQQALKEFD IVKFSLDAID LKAFERVDKP 150
YSKDINKILE GILRFSQIYQ GQLVAEVLLI KGVNDSANNL KLIAAFLKQI 200
NIARVDLSTI DRPSSFKAPK LSEDELLKCS LFFEGLCVSL PKRSITQAKK 250
LISCGIDELL ALISRRPLSA EEAPLILDSN AFKHLETLLN HKQITIKKVG 300
SLEFYCAF 308
Length:308
Mass (Da):34,405
Last modified:November 1, 1997 - v1
Checksum:iBBAA863283FBDF4B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD07185.1.
PIRiE64534.
RefSeqiNP_206917.1. NC_000915.1.
YP_006934040.1. NC_018939.1.

Genome annotation databases

EnsemblBacteriaiAAD07185; AAD07185; HP_0117.
GeneIDi13869296.
900364.
KEGGiheo:C694_00580.
hpy:HP0117.
PATRICi20591449. VBIHelPyl33062_0124.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE000511 Genomic DNA. Translation: AAD07185.1 .
PIRi E64534.
RefSeqi NP_206917.1. NC_000915.1.
YP_006934040.1. NC_018939.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-3297N.
IntActi P56080. 2 interactions.
MINTi MINT-175797.
STRINGi 85962.HP0117.

Proteomic databases

PRIDEi P56080.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAD07185 ; AAD07185 ; HP_0117 .
GeneIDi 13869296.
900364.
KEGGi heo:C694_00580.
hpy:HP0117.
PATRICi 20591449. VBIHelPyl33062_0124.

Phylogenomic databases

eggNOGi COG0731.
OMAi ISCGIDE.
OrthoDBi EOG6TTVP9.

Enzyme and pathway databases

BioCyci HPY:HP0117-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
InterProi IPR013785. Aldolase_TIM.
IPR007197. rSAM.
[Graphical view ]
Pfami PF04055. Radical_SAM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 700392 / 26695.

Entry informationi

Entry nameiY117_HELPY
AccessioniPrimary (citable) accession number: P56080
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: September 3, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Helicobacter pylori
    Helicobacter pylori (strain 26695): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3

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